Can a drink trick your appetite hormones? small study investigates
NCT ID NCT06966570
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed pilot study looked at how two different beverages—one with mixed nutrients and one with a single nutrient—affect appetite hormones and hunger ratings in 12 healthy adults aged 20 to 50. Participants drank each beverage on separate days, and researchers measured hormone levels and appetite scores. The goal was to understand the body's short-term response to different drink compositions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Mixed-macronutrient beverage and single-macronutrient beverage
- What this could lead to
- If successful, this could help researchers understand how different types of drinks affect hunger and fullness hormones, potentially guiding future appetite-control products.
- What could go wrong
- This is a very small pilot study with only 12 healthy adults, so results may not apply to the general population. It does not test weight loss or long-term effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
12 people
The number who actually took part.
- Started
-
Apr 2025
- Finished
-
Jun 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
20 to 50 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Males and females, ≥20 to ≤50 years of age. 2. BMI ≥18.5 and \<25.0 kg/m2. 3. Self-reported regular consumer (≥5 days/week) of breakfast. 4. Women who are either pre- or post-menopausal. Premenopausal women that are not using hormonal contraceptives must have a history of regular menstrual cycles (21-35 d per cycle or at the investigator's discretion) for at least 3 months prior. 5. Willing to use personal smart phone and capable of downloading the Cronometer app for diet records. 6. Willing to adhere to all study procedures, including lifestyle considerations, and sign forms providing informed consent to participate in the study and authorization to release relevant protected health information to the Clinical Investigator. Exclusion Criteria: 1. Is currently following, or planning to be on, a weight loss regimen at any time prior to or during the study. 2. Weight loss or gain \>4.5 kg within 90 days. 3. History of gastrointestinal surgery for weight reducing purposes. 4. History of an eating disorder (e.g., anorexia nervosa or bulimia nervosa, binge eating) or extreme dietary habits (e.g., ketogenic, very high protein, very high fiber, vegan, vegetarian) at the discretion of the Clinical Investigator. 5. History of unconventional sleep patterns (e.g., night shift) or a diagnosed sleep disorder or chronic medical condition that may impact appetite (in the judgment of the Investigator). 6. Use of tobacco/nicotine products (e.g., cigarette smoking, vaping, chewing tobacco) within 12 months. 7. Use of hemp/marijuana products within 60 days. Occasional use (e.g., once or twice a month) within 60 days is allowed. 8. Unstable use of any prescription medication, where stable use is defined as no change in dose or medication type within 90 days. 9. Unstable use (initiation or change in dose) within 30 days of hormonal contraceptives. 10. Use of any dietary supplements, except for a conventional once daily multivitamin/mineral supplement. 11. Recent history of (within 12 months) or strong potential for alcohol or substance abuse. 12. Exposed to any non-registered drug product within 30 days prior. 13. A score of \<7 on the Vein Access Scale Assessment. 14. History or presence, on the basis of the medical history or screening labs, of clinically important cardiac, renal, hepatic, endocrine (including diabetes mellitus), pulmonary, gastrointestinal, biliary, pancreatic, or neurological disorders that may affect the participant's ability to adhere to the study protocol and/or affect study outcomes, in the judgment of the Investigator. 15. Uncontrolled hypertension (systolic blood pressure ≥160 mm Hg or diastolic blood pressure ≥100 mm Hg). 16. Known allergy to any ingredients contained in the study product or study foods. 17. Any signs or symptoms of active infection of clinical relevance (e.g., urinary tract or respiratory) within 5 days. 18. History or presence of cancer in the prior 2 years, except for non-melanoma skin cancer. 19. History of any major trauma or major surgical event within 2 months. 20. Female who is pregnant, planning to be pregnant during the study period, lactating, or is of childbearing potential with unstable use (initiation or change in dose within 30 days) of sex hormones for contraception. 21. An employee or representative who has a financial interest in Shaklee Corporation. 22. Any condition the Investigator believes would interfere with the participant's ability to provide informed consent or comply with the study protocol, which might confound the interpretation of the study results or put the person at undue risk.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Healthy are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Biofortis Clinical Research
Addison, Illinois, 60101, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a chewable postbiotic tablet keep plaque and gum inflammation at bay?
- Can a new oral drug safely help older adults manage weight?
- Can a protein powder with creatine and fiber boost everyday Well-Being?
- Green tech or hidden stress? bus Drivers' hearts monitored behind the wheel
- Shout it out: can growls and screams raise pain tolerance?
- Scientists probe why brain stimulation works for some and not others