Assiut University

This study tests a program called contingency management, which gives rewards to people with opioid use disorder for staying drug-free and sticking with their treatment. Researchers will enroll 55 adults in a hospital setting to see if this approach reduces relapse risk and incre…

This study tests a new way to guide fluid treatment in patients with septic shock to prevent acute kidney injury. Researchers will use a non-invasive arm cuff to measure blood flow pressure and guide resuscitation, comparing it to standard care. The trial involves 100 adults in t…

This study tests a surgery called lunocapitate fusion for people with wrist arthritis caused by an old, untreated scaphoid fracture (SNAC wrist). The surgery fuses two wrist bones to reduce pain and keep some movement. Researchers will follow 35 adults for 12 months to see how we…

This study looks at whether using a non-invasive ventilator (BiPAP) at home can help people with severe COPD who have high carbon dioxide levels. Forty adults will use the machine nightly for a period, and researchers will track changes in their blood gases, how often they use th…

This study tests a new surgical method to treat pelvic organ prolapse, a condition where pelvic organs drop from their normal position. Ten women having a hysterectomy will receive a special type of suspension using their own ligaments. The goal is to see if this technique improv…

This study tests a set of emergency steps called the MINUTES bundle for patients with undifferentiated shock (dangerously low blood pressure from an unknown cause). The goal is to restore blood pressure and organ blood flow within 6 hours. About 202 adults aged 18-65 will take pa…

This study compares two surgical methods to treat children who have repeated kneecap dislocations. One surgery fixes only the main ligament (MPFL), while the other also fixes a second ligament (MPTL). The goal is to see which approach better prevents future dislocations and impro…

This study compares two surgical techniques for children aged 5 to 10 who have relapsed clubfoot with a specific foot deformity called metatarsal adductus. One surgery involves cutting and realigning a bone in the midfoot, while the other uses a small plate to slow growth on one …

This study compares a single injection of nanofat (processed fat) against PRP injections or daily topical minoxidil for treating male and female pattern hair loss. Sixty adults aged 18-50 with confirmed androgenetic alopecia will be enrolled. The goal is to see if nanofat offers …

This study compares different surgical methods to treat severe gynecomastia (enlarged male breasts) in 45 men aged 18-60. The goal is to see which technique gives the best patient satisfaction and scar appearance. Participants will have one of several procedures, and results will…

This study tests two ways to treat keloids (raised, thick scars). One uses a freezing technique alone; the other adds injections of two medicines (5-fluorouracil and triamcinolone acetonide) after freezing. About 32 adults with keloids that are 1-10 cm wide and at least one year …

This study tests whether taking the antibiotic moxifloxacin at regular intervals can lower the number of serious lung infections (exacerbations) in adults with bronchiectasis (not due to cystic fibrosis). About 140 participants will receive either the antibiotic plan or standard …

This study tests a surgery called selective dorsal rhizotomy to reduce muscle stiffness (spasticity) caused by traumatic brain or spinal cord injury. The surgery cuts certain nerve roots in the spine to relax tight muscles. Researchers will measure changes in muscle tone and elec…

This study compares two surgical implants used to treat cervical degenerative disc disease (worn-out discs in the neck). Forty adults who need neck surgery will receive either a traditional cage or a newer cage with built-in screws. The goal is to see which implant leads to bette…

This study compares two gels—hyaluronic acid gel and petroleum jelly—to see which is better at stopping nosebleeds. About 50 people with nosebleeds that start in the front of the nose will be treated with one of the gels. The main goal is to see which gel stops the bleeding compl…

This study looks at a new surgical method for certain hip fractures where the side wall of the bone is weak. Doctors will use both a nail inside the bone and a plate on the outside to hold the fracture in place. The goal is to see if this combined approach helps the bone heal cor…

This study tests a minimally invasive procedure that uses heat (radiofrequency or microwave) to destroy tumors or painful growths in the abdominal wall. It is for 30 people who cannot have surgery or choose not to. The goal is to see if this approach is safe and effective, offeri…

This study compares three treatments for non-genital warts: ivermectin cream alone, ivermectin cream combined with microneedling, and standard salicylic acid. About 88 people aged 11 to 80 will receive treatment every two weeks for up to three months. The goal is to see which app…

This study compares a plant-derived gel (B-sitosterol) with plain Vaseline for people who get frequent nosebleeds without a known cause. About 162 participants will apply one of the two gels inside their nose to see which one reduces bleeding episodes better. The goal is to find …

This study compares two types of cartilage grafts (thin vs. thick) used to repair holes in the eardrum. Thirty adults with chronic ear drum perforations will receive one of the two grafts during endoscopic surgery. The main goal is to see which graft has a higher success rate at …

This study will compare two heart failure medications—sacubitril/valsartan and captopril—in 70 children aged 1 month to 18 years who have dilated cardiomyopathy (an enlarged, weak heart). The goal is to see which drug improves the heart's pumping ability more over 12 months. Chil…

This study looks at how a medicine called sacubitril/valsartan affects the heart's ability to relax and fill with blood in people who have heart failure with reduced pumping strength. About 70 participants will take the drug for six months and have heart ultrasounds to measure ch…

This study looks at a new surgical technique for repairing cut tendons in the hand that does not require a splint afterward. Forty adults with clean-cut tendon injuries will have surgery using a special numbing method that keeps them awake, then start moving their fingers gently …

This study looks at two methods of giving a common type of antibiotic (beta-lactam) to adults with sepsis or septic shock in the ICU. One method gives the drug continuously over time, while the other gives it in short bursts. The goal is to see which approach helps more patients …

This study compares two advanced heart valves (SAPIEN 3 Ultra Resilia vs Evolut FX) in 200 people with severe aortic stenosis who need a valve replacement. Participants are randomly assigned to receive one valve, then followed for a year to see which performs better and has fewer…

This study looks at whether a 12-week, supervised exercise program (cardiac rehab) can improve how the heart pumps and rebuilds after a heart attack treated with a stent. About 100 adults who recently had a heart attack will either join the rehab program or receive standard care.…

This pilot study tests a new surgical technique called Active Apex Correction (APC) for children under 10 with progressive early onset scoliosis. The goal is to see if the surgery can safely straighten the spine and increase its length. The study will enroll 15 children who have …

This study tests two treatments—essential phospholipid and betaine HCL/L-glutamic acid—in 200 adults with metabolic fatty liver disease (MAFLD). The goal is to see which one reduces liver fat more effectively. Participants must be over 18 and diagnosed with fatty liver, but canno…

This study tests a simple surgery where a piece of the patient's own vein is wrapped around a repaired nerve in the arm or hand. The goal is to reduce scar tissue and painful nerve growths (neuromas) that often cause long-term pain and disability. About 43 adults with recent nerv…

This study compares two surgical techniques for lumbar fusion in people with painful disc problems. One uses two straight cages, the other a single banana-shaped cage. Researchers will measure success rates, recovery time, and complications to see which approach is better.

This study tests whether a new approach called 'woundsome revascularization' can save more legs in people with severe artery disease that threatens the limb. It involves 50 adults with chronic limb-threatening ischemia who need a procedure to reopen blocked arteries below the kne…

This study looks at whether sildenafil, a drug often used for other conditions, can improve heart function in children aged 1 to 18 with dilated cardiomyopathy (an enlarged, weak heart). Researchers will measure changes in the heart's pumping ability over time. The goal is to see…

This study tests whether injecting a chemotherapy drug directly into pancreatic tumors using a special endoscope, combined with standard chemo, works better than standard chemo alone. The trial involves 20 adults with locally advanced pancreatic cancer that hasn't spread. The goa…

This phase 2 trial tests a more intense chemotherapy regimen (gemcitabine and cisplatin) given before surgery to remove the bladder in people with muscle-invasive bladder cancer. The goal is to see if this approach can completely eliminate the tumor before surgery, improving long…

This study looks at children aged 18 months to 6 years who have surgery for hip dislocation. After surgery, they wear a hip cast for either 6 or 12 weeks. The goal is to see if a shorter time in the cast works just as well and helps kids get back to walking sooner.

This study tests a shorter course of radiation (3.5 Gy per session for 17 sessions) for people with early-stage glottic cancer (T1-T2N0M0). The goal is to keep the cancer under control while preserving the voice and reducing hospital visits. About 70 adults who haven't had prior …

This study tests whether a cream called terbinafine hydrochloride can treat fungal ear infections (otomycosis). About 50 adults will have the cream applied inside the ear every two days for two weeks. The goal is to see if it clears the infection and relieves symptoms like itchin…

This study compares two surgical techniques for choanal atresia, a condition where babies are born with blocked nasal passages. About 30 children up to 6 years old will receive either endoscopic choanal canalization with mitomycin C or an endoscopic crossover flap technique. The …

This study tests whether giving a rectal dose of misoprostol before a planned C-section, on top of standard oxytocin, can reduce blood loss during and after surgery. About 282 women having a planned C-section will be randomly assigned to receive either oxytocin alone or oxytocin …

This study tests whether an extra dose of radioactive iodine can help people with differentiated thyroid cancer whose tumor marker (thyroglobulin) stays high but whose scans show no visible cancer. About 100 adults who have already had their thyroid removed and standard radioacti…

This study compares two methods of closing the skin after open appendix surgery: standard interrupted stitches versus a hidden stitch plus a small drain under the skin. The goal is to see which method leads to fewer wound infections and better healing. About 100 people having ope…

This study tests whether giving magnesium sulfate early through a vein can reduce dangerous artery spasms in the brain after a traumatic head injury that caused bleeding. About 50 adults aged 18 to 65 with this type of brain bleed will receive the treatment within 24 hours of inj…

This study compares two treatments for a specific type of elbow fracture in children (Gartland type II). One group will be treated with a cast (conservative), the other with surgery. The goal is to see which approach leads to better arm function, faster recovery, and fewer compli…

This study looks at a special surgery for children who lost the top part of their thigh bone (the growth plate and joint surface) due to a severe hip infection. The surgery moves a piece of bone from another part of the leg to rebuild the hip. Researchers will check how well the …

This study looks at people with locally advanced rectal cancer who have small leftover spots in the rectum after chemoradiation. Doctors want to see if removing these spots with a scope (endoscopic resection) leads to better 1-year cancer control than simply watching them closely…

This study tests whether a nebulized drug called dexmedetomidine can prevent dangerous blood pressure spikes when a breathing tube is placed in women with severe preeclampsia undergoing cesarean section under general anesthesia. About 100 participants will receive the treatment, …

This study tests a drug called romiplostim in 100 children aged 1 to 18 with chronic ITP, a condition where the immune system destroys platelets, causing bleeding. The drug aims to safely increase platelet counts to safe levels for at least 6 weeks out of 48, without needing resc…

This study will test how well a special camera-guided (endoscopic) surgery can completely remove tumors in the nasal cavity and sinuses that are in difficult spots. About 25 people with these tumors will take part. The main goal is to see how often the tumor can be fully removed,…

This study looks at how well different biologic medications control inflammatory bowel disease (Crohn's and ulcerative colitis) after one year of treatment. About 95 adults with moderate-to-severe disease will be followed to see if they achieve remission without steroids, avoid h…

This study compares three different surgical methods for managing placenta accreta, a condition where the placenta grows too deeply into the uterine wall. The goal is to find which approach causes the least blood loss during delivery. The trial will enroll 42 pregnant women diagn…

This study tests whether using keyhole surgery (laparoscopy) to drain a liver abscess is safer and more effective than standard open or needle drainage. It will include 30 adults whose abscess is large, has come back, or could not be treated with usual methods. The goal is to see…

This study tests a surgical technique to cover deep wounds on the lower leg, ankle, heel, or foot. Doctors move a piece of skin and tissue from the outer calf to the wound, keeping it alive with a special blood supply. The study will include 30 adults and will measure how well th…

This study looks at whether a 12-hour treatment with N-Acetylcysteine works as well as the standard 21-hour treatment for children who have taken too much acetaminophen (paracetamol). The goal is to see if the shorter treatment is safer and just as effective at preventing liver d…

This study compares two common procedures for removing small kidney stones (less than 15 mm) located in the lower part of the kidney. About 70 adults will be randomly assigned to receive either flexible ureteroscopy (a thin scope through the urinary tract) or shock wave lithotrip…

This study will look at how often an upper endoscopy (a camera test to see the stomach and upper gut) finds a clear cause for long-term belly pain in children aged 6 to 18. The goal is to understand how useful this test is for diagnosing problems in kids with chronic pain that li…

This study looks at whether using multiple ultrasound techniques together can more accurately tell if a thickened area in the upper digestive tract is cancerous or not. About 43 adults with unexplained thickening seen on CT or MRI scans will undergo a special endoscopic ultrasoun…

This study will check if two blood markers (MPV and SIRI) can help doctors diagnose and predict how serious a heart attack or unstable angina is. About 300 adults with acute coronary syndrome will have their blood tested within 24 hours of symptoms. The goal is to see if these ma…

This study tests whether a 10-minute fetal heart rate recording (CTG) is as accurate as the usual 30-minute test for checking baby well-being during labor. Researchers will compare both methods in 200 low-risk pregnant women to see if the shorter version can safely detect signs o…

This study will test a new tool called the STAR score, which combines a quick belly ultrasound with simple blood tests, to see if it can better predict internal injuries in adults who have had a hard hit to the belly (like from a car crash or fall). About 129 adults aged 18 to 60…

This study will check if two blood test measurements (AST/ALT ratio and MPV/platelet count ratio) are different in people with breast cancer compared to healthy people. Researchers will look at medical records of 110 women newly diagnosed with breast cancer and compare them to a …

This study aims to see if an Arabic version of the SAMANTA questionnaire can reliably diagnose heavy menstrual bleeding in women aged 15 to 45. Heavy periods affect up to half of women and can cause anemia and lower quality of life, but simple diagnostic tools are lacking in many…

This study looks at how a procedure called gastrointestinal endoscopy (using a thin, flexible tube with a camera) can help find the reason why some children are not growing or gaining weight as expected. About 50 children aged 6 months to 18 years with failure to thrive and possi…

This study will compare two types of scans—PET/CT and regular CT—to see which one is better at finding cancer that has spread to other parts of the body in people with breast cancer. About 97 patients with advanced breast cancer will receive both scans, and the results will be co…

This study will test whether a type of MRI scan called arterial spin labelling (ASL) can help doctors determine how aggressive a child's brain tumor is before surgery. About 20 children aged 18 or younger with newly diagnosed brain tumors will receive the scan. The results will b…

This study aims to create a better way to use ultrasound to tell the difference between two serious pregnancy complications: placenta accreta spectrum and uterine scar dehiscence. Researchers will scan 50 pregnant women in their third trimester who have a low-lying placenta and a…

This study will check how accurate a special CT scan (CT KUB) is at telling harmless kidney cysts from ones that might be cancer. About 200 people with kidney cysts found on a CT KUB will take part. Their CT results will be compared with ultrasound and, for some, a follow-up CT w…

This study looks at whether mammogram and ultrasound images can predict the molecular subtype of breast cancer (like Luminal A/B, HER2-enriched, or triple-negative) without needing a biopsy. Researchers will compare imaging features to lab results from 122 women with suspected or…

This study looks at whether ultrasound can catch complications like re-rupture or infection soon after hand tendon repair. About 50 adults who had tendon surgery will get ultrasound checks, and doctors will compare those results with standard exams. The goal is to see if ultrasou…

This study looks at whether a chest ultrasound, which is painless and non-invasive, can accurately tell the difference between two types of fluid buildup around the lungs. Normally, doctors must insert a needle into the chest to draw fluid for lab testing, which carries some risk…

This study looks at whether combining a blood test for H. pylori bacteria with a painless stomach ultrasound can accurately predict serious complications from peptic ulcers, like bleeding or a hole in the stomach. Currently, doctors often need to use an invasive camera test (endo…

This study looks at whether a special MRI scan can tell the difference between two common causes of stroke: hardening of the brain's arteries (atherosclerosis) and inflammation of the blood vessels (vasculitis). About 46 people who recently had a stroke will get this MRI. The goa…

This study will check if a special ultrasound technique called elastography can help doctors tell whether growths in the chest or digestive tract are harmless or cancerous. About 35 adults will get an endoscopic ultrasound with elastography, and the results will be compared to ti…

This study checks if a new physical exam (Said's test) can better diagnose biceps tendon injuries in the shoulder. About 144 adults with shoulder pain and healthy volunteers will be examined by two doctors using the new test and standard tests. Results will be compared to MRI or …

This study looks at whether a standard chest X-ray can help find congenital heart disease in newborns. Researchers will study 60 babies in the NICU who show signs of heart issues. Each baby gets a chest X-ray within 24 hours and an echocardiogram within 72 hours to confirm the di…

This study aims to see if measuring two substances in the blood, Talin-1 and Cripto-1, can help diagnose colorectal cancer. Researchers will compare levels in 70 newly diagnosed patients with healthy people. The goal is to find a better, less invasive way to spot the disease earl…

This study looks at how well nerve tests and ultrasound can detect nerve damage in people with diabetes. Researchers will compare results from diabetic patients and healthy volunteers to find better ways to diagnose diabetic peripheral neuropathy early. The goal is to improve man…

This study will see if a special CT scan can find heart and other body problems in children with a serious heart condition called Tetralogy of Fallot. About 37 children, from newborns to 12 years old, will get the scan to help doctors plan surgery better. The goal is to improve d…

This study looks at whether MRI can better detect knee joint damage in adults with hemophilia compared to standard X-rays. About 95 participants will receive both scans to see which method gives clearer information about joint health. The goal is to help doctors choose the best t…

This study will test whether combining standard MRI with two advanced imaging techniques—volumetry and diffusion tensor imaging—can more accurately locate the seizure focus in people with temporal lobe epilepsy. Researchers will compare these MRI results with clinical outcomes to…

This study looks at whether a simple ultrasound can be as good as a colonoscopy for checking how active ulcerative colitis is. Researchers will compare ultrasound scores with colonoscopy results in 200 adults with active UC. If ultrasound works well, it could offer a less invasiv…

This study will test a new, less invasive biopsy method called transcervical true-cut biopsy to diagnose uterine masses. The goal is to see if it can accurately tell whether a mass is cancerous or benign, helping women avoid unnecessary surgery for harmless growths while ensuring…

This study will test whether artificial intelligence (AI) can accurately tell the difference between inflammatory arthritis (like rheumatoid arthritis) and degenerative arthritis (like osteoarthritis) in people aged 60 and older. Researchers will compare the AI's readings of X-ra…

This study will use a test called high-resolution anorectal manometry to find the cause of severe, long-lasting constipation in 54 children aged 4 to 18. The test measures pressure and sensation in the rectum and anus. The goal is to identify specific problems, like poor muscle c…

This study will check how well a special type of scan (PET-CT) finds cancer and helps doctors decide on treatment in people who have already been treated for colorectal cancer. About 46 adults will be followed for 5 years as part of their routine care. The goal is to see if this …

This study will check if a special ultrasound scan (FibroScan with CAP) can accurately measure fat in the liver without needing a needle biopsy. About 100 potential liver donors will get both tests, and the scan results will be compared to the standard biopsy. If the scan works w…

This study will check how well an ultrasound scoring system called O-RADS can tell if an ovarian mass is cancerous or not. About 80 women aged 18 to 70 with an ovarian cyst or mass will get standard care, including ultrasound and possibly surgery. The goal is to see if O-RADS mat…

This study aims to see if a special ultrasound technique called shear-wave elastography can better detect tendon inflammation in people with psoriasis and psoriatic arthritis. Researchers will compare this method with standard ultrasound and also look at a protein called SIRT2 in…

This study looks at how helpful endoscopy (a camera test for the stomach and intestines) is for finding the cause of digestive problems in children. Researchers will study 150 children from birth to 18 years old who need this test for issues like chronic diarrhea, vomiting, bleed…

This study looks at whether non-invasive tests (like blood counts and spleen size) can accurately predict the presence and severity of esophageal varices in children with portal hypertension. Researchers will compare these markers to the gold-standard endoscopic exam in 51 childr…

This study compares triphasic CT scans with EUS-guided biopsies to see which method more accurately identifies whether pancreatic lesions are benign or malignant. About 50 adults with suspicious pancreatic growths will undergo both tests, and results will be checked against final…

This study looks at whether a substance in the blood called sCD163 can help doctors find HELLP syndrome early in pregnancy. HELLP is a rare but serious condition that can harm the liver and blood. Researchers will compare sCD163 levels in 70 pregnant women—some with HELLP and som…

This study will compare two imaging methods—18F-PSMA PET/CT and standard CT—in men with prostate cancer. The goal is to see if the newer scan is better at finding cancer initially, tracking how well treatment works, and detecting cancer that has come back. About 59 participants w…

This study tests a new ultrasound technique to detect fetal anemia earlier and more accurately. Researchers will compare a new measurement (acceleration time) with the standard method in 20 fetuses with anemia or high cardiac output. The goal is to improve early diagnosis and tim…

This study looks at whether measuring two specific genes (NEAT1 and ANRIL) in a blood sample can help diagnose inflammatory bowel disease (IBD) without needing a colonoscopy. Researchers will enroll 62 newly diagnosed IBD patients and compare their gene levels to their symptoms a…

This study tests two methods—a surgical window or a special drain—to prevent atrial fibrillation (a common irregular heartbeat) and other heart sac complications after coronary artery bypass surgery. About 122 adults having their first bypass will be randomly assigned to one of t…

This study tests whether placing vancomycin powder inside the surgical wound during shunt placement can prevent infections in children with hydrocephalus. About 164 children, from newborns to 18 years old, having their first shunt surgery will be enrolled. The goal is to see if t…

This study looks at whether giving a combination of anti-nausea drugs before surgery can prevent nausea and vomiting in women having their gallbladder removed. About 102 adult female non-smokers will receive either granisetron plus dexamethasone or granisetron plus metoclopramide…

This study tests whether giving anti-epileptic drugs right after a traumatic brain injury can prevent seizures. Researchers will follow 70 patients for 3 months to see how many have seizures and how well they recover. The goal is to find a safe way to protect the brain and improv…

This study compares two surgical techniques for removing kidney stones larger than 2 cm. One method uses a special flexible tube with suction, and the other uses suction directly through the scope. The goal is to see which approach is faster, removes more stone, has fewer complic…

This study looks at whether placing a small drain to let out leftover gas after gynecologic laparoscopic surgery can reduce shoulder pain. Many women feel this pain because the gas used during surgery irritates the diaphragm. About 124 women having this surgery will be randomly a…

This study tests whether a superficial cervical plexus block, a numbing injection in the neck, can reduce pain after maxillofacial surgeries like lymph node biopsies or abscess drainage. About 70 adults will be randomly assigned to receive the block or standard care. Researchers …

This study tests whether propofol or lidocaine works better to prevent confusion and agitation in children waking up from tonsillectomy. About 82 kids aged 4 to 7 will receive one of the two medicines during anesthesia. The goal is to find a safer, calmer recovery for young patie…

This study tests a surgical technique for women with moderate to severe breast sagging (ptosis). The procedure uses the patient's own skin and fat to lift the breast and add fullness, avoiding artificial implants. Researchers will measure changes in breast shape and patient satis…

This study compares early task-oriented rehabilitation (practicing real-life activities like walking or dressing) with traditional physical therapy for people who recently had a stroke. About 158 adults with ischemic or hemorrhagic stroke will start therapy within 48 hours and be…

This study looks at two methods of closing the skin after a stoma reversal operation in children. One method uses a purse-string stitch, the other a straight-line closure. The goal is to see which method leads to fewer wound infections and a nicer-looking scar. Fifty children wil…

This study looks at a surgery called calcaneal osteotomy for people with long-lasting plantar fasciitis (heel pain) that hasn't gotten better with other treatments. The surgery cuts and shifts the heel bone to reduce strain on the plantar fascia without cutting it. Researchers wi…

This study compares two types of nerve blocks for pain relief in children aged 1-6 years undergoing surgery for hypospadias, a common birth defect of the penis. One method is the standard caudal block, and the other is a newer sacral erector spinae plane block, both given with th…

This study compares two types of nerve blocks (ESPB and QLB) to see which provides better pain relief after kidney surgery in children aged 2-12. The goal is to find which method delays the need for extra pain medicine and reduces overall pain and side effects. 100 children will …

This study compares a procedure called POEM for treating achalasia, a swallowing disorder. It will look at 32 adults who either have POEM as their first treatment or after a prior balloon dilation failed. The goal is to see if prior balloon treatment affects how well POEM works a…

This study compares two sedative drugs, dexmedetomidine and ketamine, given through a vein to help men relax during varicocelectomy surgery performed under spinal anesthesia. The goal is to see which drug provides better sedation and fewer side effects. Fifty-eight male patients …

This study looks at whether placing children in a specific position when their breathing tube is removed after sleep apnea surgery can lower the chance of dangerously low oxygen levels. About 262 children aged 2 to 10 having tonsil or adenoid removal will be randomly assigned to …

This study compares two medications, dexmedetomidine and midazolam, to see which is better at preventing shivering in trauma patients having leg surgery under spinal anesthesia. Shivering is a common side effect that can cause discomfort and complications. The trial will enroll 1…

This study compares two surgical approaches for degenerative lumbar spinal stenosis, a condition that causes back and leg pain. Researchers will enroll 56 adults over 40 who still have pain after at least 3 months of non-surgical treatments. One group will have a less invasive su…

This study looks at whether adding a special tape to standard ACL surgery helps the knee heal better and lets people return to normal activities sooner. About 114 people aged 15 to 50 with an ACL tear will be split into two groups: one gets the standard surgery, the other gets th…

This study compares two minimally invasive treatments for chronic plantar fasciitis, a common cause of heel pain. One uses pulsed radiofrequency to desensitize nerves, the other uses steroid injections to reduce inflammation. 122 adults with persistent heel pain will be randomly …

This study tests a new cream made with tiny particles of apremilast for people with mild to moderate plaque psoriasis. About 36 adults will use either the new cream, a steroid cream, or both for 12 weeks. The goal is to see if the new cream reduces redness, thickness, and scaling…

This study tests whether adding magnesium sulfate or lidocaine to a standard sedative (dexmedetomidine) better prevents coughing after functional endoscopic sinus surgery. Coughing after this surgery can cause bleeding and slow recovery. About 102 adults will be randomly assigned…

This study tests a 3-month rehabilitation program for people with COPD, a chronic lung disease. The program includes exercises done both in the hospital and at home. Researchers want to see if it helps patients walk farther and feel better. About 70 adults over 40 with moderate t…

This study tests whether adding phenol injections to standard botulinum toxin treatment works better for reducing arm stiffness in stroke survivors. About 60 adults who had a stroke at least 6 months ago will receive either the combined therapy or botox alone. The goal is to see …

This study compares two types of nerve blocks for shoulder surgery pain. The standard block can sometimes cause breathing problems by paralyzing part of the diaphragm. The new approach uses a different combination of blocks lower in the neck to avoid this side effect. Researchers…

This study tests a non-invasive brain stimulation technique called rTMS in children aged 6-19 with ADHD or autism. Over three weeks, some children receive real stimulation while others get a sham (fake) treatment. The goal is to see if rTMS can safely reduce core symptoms like in…

This study tests whether adding either dexmedetomidine or magnesium sulfate to standard spinal anesthesia can improve pain control and recovery for adults undergoing hip fracture repair. About 92 patients will receive one of the two additives, and researchers will measure how qui…

This study compares two types of neck surgery for people with cervical spinal stenosis—a condition where the spine narrows and presses on nerves. The goal is to see which surgery better improves nerve function and has fewer complications. Only 2 adults aged 40 or older who need s…

This study tests whether injecting platelet-rich plasma (PRP) into the wound after fistulotomy surgery for simple anal fistula can speed up healing and reduce pain. About 70 adults will be randomly assigned to receive either standard surgery plus PRP or standard surgery alone. Th…

This study tests whether adding dexmedetomidine to a standard numbing medicine (bupivacaine) in a nerve block can reduce the amount of strong painkillers (opioids) needed after upper abdominal cancer surgery. About 54 adults aged 18-70 having surgery for stomach, liver, or pancre…

This study tests whether taking a low-dose daily pill (tadalafil 5 mg) can reduce urinary leakage and other bothersome bladder symptoms in men recovering from prostate surgery for an enlarged prostate. About 40 men will be randomly assigned to receive either the drug or a placebo…

This study compares virtual reality (VR) therapy to standard balance exercises for people with chronic dizziness. Researchers will enroll 40 adults aged 18-70 who have had dizziness for over 3 months due to inner ear problems. The goal is to see if VR can improve dizziness and ba…

This study tests whether injecting a person's own fat (nanofat) into facial acne scars works better when combined with platelet-rich fibrin or microneedling. 42 adults with moderate to severe scars will be treated and followed for 3 months. The goal is to see which method improve…

This study compares two medicines, dexmedetomidine and lidocaine, to see which one helps place a breathing tube (laryngeal mask) more easily in children aged 2-12 having minor surgery. The goal is to improve success on the first try and reduce coughing or other breathing problems…

This study tests whether breathing in N-acetylcysteine (a mucus-thinning drug) works better than getting it through a vein for people with bronchiectasis, a lung condition that causes thick mucus. About 70 adults hospitalized with a flare-up will be randomly assigned to one of th…

This study compares two drugs, dexmedetomidine and nalbuphine, added to a standard numbing shot for arm surgery. The goal is to see which one provides longer pain relief after the operation. 66 adults having elective upper arm surgery will take part. The results could help improv…

This study will compare two medications, dexmedetomidine and fentanyl, given through a vein during general anesthesia for major abdominal cancer surgery. The goal is to see which drug better maintains heart function and stable blood pressure. About 70 adults undergoing elective s…

This study tests a new treatment for burn scars on the chest, shoulders, and back. Doctors will take a small amount of fat from the patient's own body, process it into a liquid rich in healing cells, and inject it into the scar. The goal is to improve the scar's look, feel, and f…

This study compares two drug combinations (dexmedetomidine vs. fentanyl-midazolam) to see which better reduces stress on the body during laparoscopic gallbladder surgery. 50 adults aged 18-65 with mild health issues will be enrolled. The goal is to find the best way to keep heart…

This study compares two surgical tools—LigaSure and bipolar diathermy—for removing part or all of the thyroid gland. Researchers will measure how long surgery takes, how much pain patients feel afterward, and the risk of low calcium levels. The goal is to find which tool leads to…

This study tests whether taking a low dose of two different erectile dysfunction drugs together works better than a standard dose of one drug. About 142 men with ED will try both treatments in a crossover design. The goal is to improve erections with fewer side effects.

This study tests whether rinsing the surgical area with a mix of ketamine and standard pain reliever (bupivacaine) reduces pain after gallbladder removal. Sixty adults having laparoscopic cholecystectomy will be randomly assigned to receive either the standard rinse or the ketami…

This study will test if using a specific type of intravenous anesthesia (TIVA) reduces nausea and vomiting after laparoscopic obstetric surgery compared to standard inhaled anesthesia. About 98 women undergoing elective laparoscopic procedures will be randomly assigned to one of …

This study looks at whether removing kidney stones right away with a scope (ureteroscopy) is safe and works well for people whose kidneys are struggling due to a blockage. Researchers will compare results in 60 adults with normal vs. reduced kidney function. The goal is to see if…

This study tests whether avoiding opioids during gallbladder surgery can reduce pain, nausea, and vomiting after the operation. About 110 adults having planned laparoscopic gallbladder removal will receive either opioid-free or standard opioid-based anesthesia. The goal is to see…

This study tests a new gel containing spironolactone (a hormone blocker) against a standard acne gel (adapalene) in 40 people with mild to moderate acne. Each person will apply one gel to one side of their face and the other gel to the other side, so the results can be compared d…

This study compares two surgical alignment methods (kinematic vs. mechanical) after a high tibial osteotomy in 100 adults with arthritic bow-legged knees. The goal is to see which approach better improves pain, function, and activity over 12 months. Participants must have tried n…

This study tests whether injecting platelet-rich plasma (PRP) into the vocal cords can improve voice quality and quality of life for people with vocal fold sulcus, scar, or atrophy. About 48 participants aged 10 and older will receive the injection and be followed over time. The …

This study looks at whether using a larger or smaller amount of fluid during an ultrasound-guided injection around the median nerve can better relieve pain in people with carpal tunnel syndrome. The trial will include 35 adults with mild to moderate symptoms. The goal is to find …

This study compares three treatments for pitted acne scars: a minor skin procedure called subcision alone, or subcision combined with either a fractional CO2 laser or platelet-rich plasma (PRP). The goal is to see which combination improves scars the most. The study will enroll 4…

This study tests whether taking tranexamic acid pills along with a skin needling treatment that delivers glutathione works better for melasma than either treatment alone. About 42 women with facial melasma will be enrolled. The goal is to reduce the dark patches and improve how p…

This study tests whether a sodium bicarbonate enema can help relieve constipation and reduce harmful waste products (uremic toxins) in people with chronic kidney disease (CKD). The idea is to use the gut as an extra route to remove toxins that damaged kidneys can't clear. The stu…

This study will test whether a gel containing dutasteride can treat facial acne better than a standard gel that combines three drugs (clindamycin, benzoyl peroxide, and adapalene). About 50 adults with acne will use one gel on half their face and the other gel on the other half f…

This study tests whether giving lidocaine through a vein during gallbladder surgery can lower inflammation and pain, and help the gut start working again sooner. About 90 adults having planned laparoscopic gallbladder removal will take part. Half will get lidocaine, half a placeb…

This study will test whether a set of recovery steps, called Enhanced Recovery After Surgery (ERAS), can help women recover faster after an emergency cesarean section. About 100 women having an emergency C-section will be enrolled. The plan includes better pain control, early eat…

This study looks at whether caffeine therapy can help stabilize the heart and blood pressure of preterm babies (born before 37 weeks) who have apnea (pauses in breathing). Researchers will monitor 40 infants in the NICU, measuring changes in blood pressure, heart rate, and blood …

This study tests whether potassium citrate, a urine alkalinizer, can relieve painful urination, urgency, and frequency in women aged 18-50 with uncomplicated UTIs. Fifty participants will take either potassium citrate or the antibiotic nitrofurantoin for 7 days. Researchers will …

This study looks at two medicines, Dexmedetomidine and Ketamine, added to a standard pain block for children aged 1 to 6 years after hip surgery. The goal is to see which one provides better pain relief, lasts longer, and reduces the need for extra pain medicine. The study will e…

This study tests a cosmetic procedure where a person's own belly fat is injected into the penis to make it thicker. It will enroll 25 men aged 21-60 who are unhappy with their size and have a flaccid girth under 11 cm. Researchers will measure changes in girth and check fat survi…

This pilot study will test whether low-intensity shockwave therapy can safely improve blood flow and ease symptoms in 30 men with erectile dysfunction caused by blood vessel problems. Participants will receive treatment using a special device, and researchers will monitor for sid…

This study tests if inflating a small balloon in the stomach outlet during surgery can prevent delayed stomach emptying, a common problem after pancreatic tumor removal. About 70 adults having this surgery will be randomly assigned to get the balloon procedure or standard surgery…

This study tests whether lidocaine, ketamine, or both given through a vein can safely reduce pain in people with orofacial pain that hasn't responded to other treatments. About 105 adults will be randomly assigned to one of three groups and followed for 6 months. The goal is to f…

This study looks at two surgical approaches to treat severe hand or underarm sweating. The goal is to see if operating on one nerve level (T3) causes less unwanted sweating in other body areas compared to operating on two levels (T3-4). About 46 people aged 6 and older with prima…

This study will check how often muscle loss (sarcopenia) happens in people with metabolic fatty liver disease. Researchers will look at 120 adults to see if muscle loss is linked to worse liver damage. The goal is to better understand these conditions, not to test a new treatment…

This study aims to learn more about breast cancer by measuring a specific genetic marker (PCGEM1) in blood and tissue samples. Researchers will compare levels in people with breast cancer to those without. The goal is to better understand how the disease develops and find new tar…

This study aims to clearly distinguish between multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD), two conditions that can look alike but need different treatments. Researchers will measure specific proteins in the blood of 100 participants aged 18 to 50 a…

This study will look at medical records of 770 women who had C-sections in two hospitals in Assiut, Egypt, during 2026. Researchers will use the WHO's Robson system to group women by their pregnancy details and see which groups have the most C-sections. The goal is to find ways t…

This study looks at whether adding a quick, painless ultrasound measurement of the neck to a standard mouth exam can better predict if placing a breathing tube will be difficult. About 160 adults having planned surgery under general anesthesia will be randomly assigned to either …

This study will check if a protein called Tim-3 on certain white blood cells (neutrophils) can help doctors measure how active ankylosing spondylitis is in a patient. Researchers will compare Tim-3 levels with standard inflammation markers and MRI scans of the spine and hips. The…

This study will measure certain proteins and cells in the blood of 75 adults hospitalized with a COPD flare-up. The goal is to see if these markers can predict how serious the episode is. Researchers hope this could lead to better, faster treatment decisions for patients.

This study looks at how a common laser treatment for advanced diabetic eye disease (called panretinal photocoagulation) affects the cells on the front surface of the eye (the cornea). Researchers will measure these cells before treatment and again at 1 week and 1 month after trea…

This study will test whether a special MRI technique called T1 mapping can find and measure tiny scars in the heart muscle of people with long-term thyroid disease. The goal is to see if this non-invasive scan can replace the need for a heart biopsy. The study will involve 40 adu…

This study compares two types of knee X-rays (full-leg standing and Rosenberg view) to see if they give different measurements of the knee angle in people undergoing high tibial osteotomy. About 49 patients with knee arthritis will be included. The goal is to find out which X-ray…

This study looks at how the thyroid and adrenal glands work in 200 ICU patients with septic shock, a life-threatening infection that causes organ failure. Researchers will measure hormone levels in the blood to see if these glands are affected. No new treatments are tested—the go…

This study looks at whether a specific cholesterol ratio (NHHR) is linked to kidney disease in people with diabetes. Researchers will measure this ratio in 84 adults with diabetes and check for signs of kidney damage. The goal is to find a simple way to identify those at higher r…

This study looks at 50 adults with glioblastoma, an aggressive brain cancer, to see how much of the tumor is removed during surgery and how follow-up chemoradiotherapy affects how long they live. Researchers will track survival from surgery onward. The goal is to better understan…

This study looks at whether having dry eye disease makes it harder for doctors to pick the right lens power before cataract surgery. Researchers will compare 100 cataract patients—some with dry eye, some without—to see if dry eye leads to less accurate vision after surgery. The g…

This study will look at 67 children with pneumonia to find which early signs predict a more serious illness. Doctors will check vital signs, lab tests, and X-rays to see which children need oxygen, ICU care, or have complications. The goal is to help doctors recognize severe case…

This study looks at whether using scissors or a scalpel to cut the uterus during a planned C-section leads to less blood loss. About 140 pregnant women, aged 18-40, having an elective C-section will take part. The goal is to find out which tool is better, but this is just for kno…

This study will observe 70 children with sudden breathing problems at Assiut University Children Hospital in Egypt. Researchers aim to find out how common these cases are, what causes them, and which children are most at risk. The goal is to improve how doctors diagnose and treat…

This study looks at how being nearsighted or farsighted affects the optic nerve and retina. Researchers will use a special camera (OCT) to measure eye structures in 266 adults. The goal is to better understand these links, not to test a treatment.

This study will check whether three common heart failure risk scores, developed mostly in Western countries, accurately predict outcomes for Egyptian patients. Researchers will follow 140 adults with heart failure for one year to see if the scores correctly predict death or hospi…

This study looks at how well ultrasound can find and describe fluid buildup in the belly (ascites) and figure out what's causing it. About 125 people with suspected ascites will get an abdominal ultrasound. The goal is to see how accurate ultrasound is for this purpose.

This study will check how often infants and children (1 month to 4 years old) with gastrointestinal diseases have electrolyte disturbances, like low sodium or potassium. Researchers will measure these imbalances in 150 children admitted to a gastroenterology unit. The goal is to …

This study looks at 200 adults with metabolic fatty liver disease to see how many also have an H. pylori infection. Researchers will use a simple stool test to find the bacteria. The goal is to understand if treating H. pylori could help manage fatty liver disease and improve pat…

This study will measure two immune proteins (IL-17A and IL-10) in the blood of 80 newly diagnosed adults with B-cell acute lymphoblastic leukemia (B-ALL) in South Egypt. Researchers want to see if these protein levels are linked to lab results and how well patients respond to tre…

This study looks at how common parasitic infections are in people with blood disorders like anemia and blood cancers. Researchers will test 285 participants in Egypt for parasites such as Toxoplasma. The goal is to better understand the link between these infections and blood dis…

This study looks at whether lead in the blood plays a role in multiple sclerosis (MS). Researchers will measure lead levels, oxidative stress markers, and DNA changes in 140 people with MS and healthy controls. The goal is to understand how lead might affect the disease, not to t…

This study looks at PET-CT scan results in people aged 60 and older who have lymphoma. The goal is to learn more about how the disease appears on these scans, which could help doctors make more accurate diagnoses and predictions. About 63 participants will be enrolled, and the st…

This study aims to understand how common violence is among women who come to the hospital with physical injuries. Researchers will look at injury patterns in 160 female patients aged 18 and older. The goal is to improve how doctors document and report these cases for legal purpos…

This study will look at 40 newborns in intensive care to understand why some develop anemia (low red blood cells). Researchers will track risk factors like mother's health and birth details, and see how anemia affects hospital stay, need for transfusion, and overall health. The g…

This study watches 160 infants aged 1-12 months who are fed a special amino acid-based formula because of cow's milk allergy or other medical reasons. Researchers will measure weight, length, and head growth over time to see if the formula supports healthy development. No new tre…

This study aims to find out how often children with epilepsy also have symptoms of ADHD, and what factors might make that more likely. Researchers will follow 185 children over 12 weeks to track changes in ADHD symptoms and quality of life. The goal is to better understand the co…

This study looks at how heart procedures affect the mental health of people with congenital heart disease. Researchers will check for depression, anxiety, and other psychiatric symptoms before surgery, one month after, and three months after. The goal is to help doctors better su…

This study compares two common methods (direct trocar insertion vs. Veress needle insertion) for starting a laparoscopic procedure in people who have had prior abdominal or pelvic surgeries. The goal is to see which method is faster and safer, especially when scar tissue may make…

This study aims to find out how common von Willebrand disease is among children in Upper Egypt, describe the different types, and see how it is currently managed. Researchers will review medical records and check bleeding symptoms in up to 25 children aged 0-18 with suspected or …

This study looks at how changes in tiny blood vessels at the back of the eye relate to vision loss in people with multiple sclerosis (MS). Researchers will use a special eye scan (OCT-A) and standard vision field tests in 32 participants. The goal is to better understand how MS a…

This study looks at how well different veins in the body collapse when a person is in shock from severe injury. Doctors will use ultrasound to measure collapse in the femoral vein, internal jugular vein, and inferior vena cava before and after giving fluids. The goal is to find t…

This study compares two medications, dexmedetomidine and magnesium sulfate, to see which better controls pressure inside the skull during brain surgery. Sixty adults having elective craniotomy will receive one of the drugs, and their brain pressure will be continuously measured u…

This study will check 200 adults with metabolic fatty liver disease for high uric acid levels, a condition that can worsen liver problems. Participants will have blood tests at the start and after 6 months to measure uric acid and liver function. The goal is to find and manage th…

This study looks at whether how often seizures happen at the start of epilepsy can help predict how well they will be controlled later. Researchers will review medical records and interview 100 people with newly diagnosed epilepsy. The goal is to find early clues that could guide…

This study looks at two standard stitching methods (interrupted vs. continuous) used to connect the kidney artery to the iliac artery during living donor kidney transplants. Researchers will review past cases and follow 70 new adult patients at Assiut University to see which tech…

This study looks at how being obese might change how well treatments work for people with inflammatory bowel disease (IBD), like Crohn's disease or ulcerative colitis. Researchers will follow 120 adults with IBD who are on standard treatments, including biologics, to see if those…

This study aims to describe the clinical, blood, and genetic features of chronic lymphocytic leukemia (CLL) in 45 newly diagnosed adults. Researchers will examine how specific genetic changes, like IGHV mutation status and del(17p), relate to treatment response. Participants will…

This study watches 120 critically ill adults without kidney injury at ICU entry to see if their fluid balance in the first 48 hours is linked to developing acute kidney injury (AKI). Researchers track fluids hourly and check kidney function for 7 days. The goal is to find better …

This study looks at how common violence is among married women (ages 18-45) who are seeking help for infertility in Egypt. Researchers want to understand if infertility makes women more likely to face abuse. The goal is to use this information to better support and protect these …

This study will track 139 newborns who have seizures in their first month of life to learn how common these seizures are, what causes them, and how the babies do during their hospital stay. Researchers will use exams, blood tests, and brain scans to gather information. The goal i…

This study will check if people with more severe sleep apnea also have higher blood pressure in their lungs. About 55 adults with sleep apnea will have their heart and lungs checked using ultrasound. No new treatments are tested—the goal is simply to understand the link between t…

This study looks at how often tendon inflammation (tenosynovitis) occurs in children with two types of juvenile idiopathic arthritis. Researchers will use ultrasound to find inflammation that might be missed during a regular physical exam. The goal is to improve early detection a…

This study will track 100 children in the intensive care unit to find out what leads to acute kidney injury. Researchers will look at factors like infections, low blood pressure, and use of breathing machines. The goal is to identify early warning signs so doctors can act faster.

This study looks at how congenital heart disease (CHD) affects growth in infants and toddlers aged 1 month to 2 years. Researchers will review medical records of 72 children to compare their weight, height, and head circumference against healthy growth standards. The goal is to b…

This study looks at children with sepsis, a severe infection that can cause organ failure, to understand how often heart injury occurs and what predicts it. Researchers will monitor 84 critically ill children aged 1 month to 18 years using blood tests and heart ultrasounds. The g…

This study explores whether the length of time a person has anal fistula symptoms before surgery impacts their healing and the chance of the fistula coming back. Researchers will follow 90 adults having surgery, grouping them by how long they had symptoms (3 months or less, 3-6 m…

This study aims to see if certain markers from a standard complete blood count (CBC) can help doctors assess how severe acute pancreatitis is and predict patient outcomes. Researchers will look at data from 100 adults treated for acute pancreatitis between 2019 and 2025. The goal…

This study will check 100 adults on long-term dialysis to see how often they have thyroid problems, abnormal cholesterol, and high uric acid. Researchers want to understand how these conditions are linked in dialysis patients. The goal is to gather information, not to test a new …

This study will follow 100 children aged 1 to 18 with myocarditis (inflammation of the heart muscle) to see how different types of the disease affect their health. Researchers will track symptoms, treatments, and recovery over one year. The goal is to better understand the diseas…

This study will track 50 children under 15 with a specific type of elbow fracture to see how often blood vessel injuries happen and what treatments work best. The goal is to learn which children are at higher risk and improve how these injuries are managed. No new treatments are …

This study aims to understand sleep breathing problems in people with systemic sclerosis (scleroderma), a condition that causes skin and organ hardening. Researchers will use overnight sleep tests (polysomnography) to measure breathing pauses in 30 adults with scleroderma. The go…

This study will look at how well bronchoscopy works to remove objects that children may have inhaled into their airways. Researchers will track how often the object is successfully removed and note any problems that happen within 24 hours, like low oxygen or bleeding. The study i…

This study will follow 645 older adults (65+) who have had a heart attack to see how frailty influences treatment choices and recovery. Researchers want to know if adding a frailty check to standard risk tools better predicts who will have serious heart problems or die within 30 …

This study aims to create a tool that helps researchers use artificial intelligence (AI) ethically. AI is now used in many steps of research, from planning to publishing. The study will ask 200 adults who have experience with research or AI to help develop and test this tool. The…

This study will check heart disease risk in 238 adults with type 2 diabetes using standard risk scores. It will also see if simple belly fat measurements can predict that risk. The goal is to find a better way to identify high-risk patients early.

This study looks at how alienation—feeling disconnected or isolated—affects the mental health, social life, and overall quality of life of medical students at Assiut University. Researchers will survey 77 students from outside the local area to understand these impacts. The goal …

This study looks at whether certain blood markers (like NLR, PLR, PNI, and SII) can predict how severe sepsis is and who might die from it. Researchers will compare these markers to standard scoring systems (SOFA and APACHE) in 61 ICU patients with sepsis. The goal is to find a s…

This study looks at children under 18 with chronic liver disease to see if they have hidden heart problems. Researchers will use simple tests like blood work, ultrasound, and heart tracings to check for conditions like high blood pressure in the lungs or changes in heart muscle f…

This study will check how a type of leukemia drug called tyrosine kinase inhibitors (TKIs) affects the thyroid gland in people with chronic myeloid leukemia (CML). Researchers will measure thyroid hormone levels in 76 newly diagnosed adults over time to see if these drugs cause t…

This study looks at how different risk factors, like iron overload from blood transfusions, affect growth in children with beta-thalassemia major. Researchers will measure height, weight, and body mass index in 85 children aged 1 to 18. The goal is to better understand what cause…

This study looks at whether a short classroom program can help teenagers in Assiut, Egypt, learn more about mental health, feel less stigma, and be more willing to seek help. About 150 students aged 13-18 will take part. The program covers basic mental health facts, reducing nega…

This study looks at 200 adults with a type of fatty liver disease called MASLD. The goal is to find out how many of them are also obese, and to learn more about the small group of patients who have a normal weight. The results will help doctors better understand this liver condit…

This study looks at whether low magnesium in the blood is linked to sleep problems in people with major depression. Researchers will measure magnesium levels and sleep quality in 90 adults. The goal is to better understand the connection, not to test a treatment.

This study aims to see if certain blood markers (MCP-1, NLR, SII, and hsCRP) can help detect kidney disease early in people with type 2 diabetes. Researchers will measure these markers in 80 adults aged 18-80 who have type 2 diabetes. The goal is to find simple tools that could l…

This study looks at the real-life challenges faced by people with Wilson's disease in Upper Egypt, a rare condition where copper builds up in the body. Researchers will survey 66 patients to understand dietary habits, emotional and social burdens, and barriers to getting care. Th…

This study looks at why some very premature babies (born before 32 weeks and weighing under 1,500 grams) fail to get enough oxygen from a mask or nasal prongs and need a breathing tube instead. Researchers will review medical records of 160 infants to find risk factors that lead …

This study will observe 65 infants and toddlers hospitalized with bronchiolitis, a common lung infection, to identify factors that make the illness more severe. Researchers will collect information from parents and medical records, including family history, symptoms, and treatmen…

This study looks at heart health in children aged 1 month to 18 years who have brain conditions like seizures, migraines, or encephalopathy. Researchers will use simple heart tests (ECG and echocardiogram) to find hidden heart problems. The goal is to understand how heart and bra…

This study will look at genetic test results from 75 children aged 1 month to 12 years who have birth defects and developmental delays. Researchers will collect medical history, do physical exams, and review karyotyping (a type of genetic test) to find chromosomal problems. The g…

This study will survey 289 medical students and interns at Assiut University to find out how many experience anxiety and depression. Researchers will also look for risk factors and see if mental health affects grades. The goal is to better understand the problem, not to test a tr…

This study looks at whether a special eye scan (OCT) can find early changes in the retina of people with diabetes who have no vision problems. About 112 participants will get a detailed eye exam, including scans and photos, to compare their eyes with healthy people. The goal is t…

This study looks at 28 women with ovarian cancer to see how well CT scans and a minimally invasive camera (laparoscopy) predict whether surgeons can remove all visible tumor during open surgery. The goal is to find the best way to plan surgery and avoid unnecessary procedures. Pa…

This study looks at how sepsis (a severe infection) affects the hearts of newborn babies. Researchers will use a special ultrasound to check heart function and compare the results with blood markers of infection and heart damage. The goal is to see if this ultrasound can help doc…

This study looks at how rising temperatures affect outdoor workers in Upper Egypt. Researchers will check workers for signs of heat illness and then test a program to reduce those risks. The goal is to see if the program helps workers stay healthier in hot conditions.

This study looks at 95 adults with complicated parapneumonic effusion (infected fluid around the lung) who need surgery. Doctors will use a scoring system and ultrasound before surgery to predict whether a simpler or more complex procedure is needed. The goal is to see if these t…

This study looks at 28 people with crossed eyes (esotropia) to see if the width of a specific eye muscle affects how well surgery corrects the condition. Researchers will measure the muscle during surgery and compare it to the amount of correction achieved. The goal is to help su…

This study will observe 100 adults with diabetes and foot ulcers to identify non-vascular risk factors—like infection, poor blood sugar control, and smoking—that make ulcers worse or slow healing. Researchers will track ulcer size and recurrence over one year. The goal is to bett…

This study will look at blood clotting problems in 80 adults newly diagnosed with acute myeloid leukemia (AML) who are about to receive strong chemotherapy. The goal is to measure changes in clotting before and after treatment to better understand bleeding risks. This is an obser…

This study will observe 85 critically ill adults in the ICU to see if acute kidney injury (AKI) makes it harder to successfully remove a breathing tube. Researchers will track how often weaning succeeds, how long it takes, and any complications. The goal is to understand if AKI i…

This study looks at how common depression, anxiety, stress, and burnout are among heart disease patients and the healthcare workers who treat them. About 380 people will fill out questionnaires to measure these mental health issues. The goal is to find out how often these problem…

This study will follow 60 children aged 1 month to 18 years who have supraventricular tachycardia (SVT), a condition where the heart beats very fast. Researchers want to see how these children do over time, what treatments work best, and how often the fast heartbeat comes back. T…

This study looks at how iron deficiency (with or without anemia) affects heart rhythm problems in 300 adults hospitalized with heart failure. Researchers will check for irregular heartbeats and ECG changes to see if iron levels can help identify high-risk patients. The goal is to…

This study will test if a detailed heart ultrasound (speckle tracking echocardiography) can detect early, hidden heart problems in 100 adults with inflammatory bowel disease (IBD). Researchers will compare these findings with standard heart tests and inflammation markers. The goa…

This study will compare two noninvasive methods—electrical cardiometry and echocardiography—for measuring how well the heart pumps blood in 100 adults with septic shock. The goal is to see if electrical cardiometry can be a reliable, easier-to-use alternative for monitoring these…

This study looks at why women who have experienced gender-based violence in Upper Egypt struggle to get good healthcare. Researchers will talk to healthcare workers and survivors to find out what gets in the way and what could help. The goal is to create recommendations to make W…

This study looks at why some children are born with a droopy eyelid (congenital ptosis) due to poor muscle development. Researchers will examine the eyelid muscle during surgery and under a microscope to understand the problem better. The goal is to learn more about the condition…

This study looks at whether low vitamin D levels are linked to higher insulin resistance in people with type 2 diabetes. Researchers will measure vitamin D and a simple blood test called the triglyceride-glucose index in 165 adults. The goal is to better understand how vitamin D …

This study examines stored tumor tissue from 70 people with a common type of breast cancer (ER-positive, HER2-negative) who received hormone therapy. Researchers will look for specific protein markers (p-AKT and p-S6) to see if they can tell which cancers are likely to respond to…

This study tests whether adding a T2 mapping sequence to a standard knee MRI can improve detection of early osteoarthritis. Researchers will compare scans from 28 healthy volunteers and 28 people with early knee OA. The goal is to see if this extra scan provides clearer informati…

This study looks at whether measuring a substance in the blood called lipoprotein(a) can help predict future heart problems in people who have had a stent placed to open a blocked artery. Researchers will follow 156 adults for one year after their procedure to see who has a heart…

This study will test 70 people with diarrhea-predominant IBS to see how many actually have lactose intolerance. Researchers will use a PCR test and a symptom questionnaire. The goal is to better understand the link between lactose intolerance and chronic diarrhea, which could hel…

This study looks at how changes in blood pressure during sleep (called dipping) relate to heart electrical activity in 140 adults with high blood pressure. Researchers will compare people whose blood pressure drops normally at night to those whose does not, to see if non-dippers …

This study will observe 200 adults getting a heart device (like a pacemaker) to see how closely doctors follow European guidelines. The goal is to find out if following these guidelines leads to fewer problems, such as infections or device issues, within the first month and up to…

This lab study looks at whether verapamil, a drug used for high blood pressure, can make antibiotics work better against drug-resistant bacteria. Researchers will test bacteria samples from 100 cancer patients to see if adding verapamil helps kill superbugs. This is early-stage r…

This study looks at whether two proteins, MMP7 and MMP9, can be used as a screening tool for interstitial lung disease (ILD) in people with rheumatoid arthritis (RA). Researchers will compare three groups: RA patients with ILD, RA patients without ILD, and healthy volunteers. The…

This study will check if a special heart ultrasound measurement (left atrium strain) can predict serious problems in the hospital after a major heart attack treated with angioplasty. About 135 adults with a first-time heart attack will have an ultrasound within 48 hours. Research…

This study will follow 225 adults with end-stage kidney disease who receive regular dialysis three times a week. Researchers want to see if missing a dialysis session raises the chance of a heart problem—like a heart attack, heart failure, or dangerous heart rhythm—within 72 hour…

This study will look at 35 children aged 1-18 with acquired aplastic anemia in Assiut, Egypt. Researchers will record their symptoms, possible causes, and how they are treated. The goal is to better understand this rare blood condition in this region.

This study looks at whether ultrasound can accurately detect when bones have healed enough during Ilizarov frame treatment. Researchers will compare ultrasound results with standard X-rays and physical exams in 56 patients. If successful, ultrasound could offer a safe, radiation-…

This study will observe 30 people with Behçet's disease in Upper Egypt to learn more about their symptoms, lab results, and treatments. The goal is to better understand how the disease shows up in this group. No new treatments are being tested.

This study looks at how the liver changes in size after radiation therapy for cancers in the belly or liver area. Researchers will use CT scans taken before and after treatment to measure liver volume changes. The goal is to better understand radiation's effect on the liver and h…

This study looks at whether ultrasound can find hidden joint inflammation in people with inflammatory bowel disease (IBD) who have no joint pain or arthritis diagnosis. Up to half of IBD patients may have such hidden issues, which are often missed by regular exams. Researchers wi…

This study looks at a protein called IL-33 in the blood of people with lupus, some of whom also have kidney problems (lupus nephritis). Researchers want to see if higher IL-33 levels are linked to more active disease or kidney involvement. The study involves 150 adults: lupus pat…

This study looks at how common epiretinal membrane (a thin scar-like layer on the retina) is in people with diabetic retinopathy, and what factors might make it more likely. Researchers will examine 225 adults with diabetes and varying stages of diabetic eye disease using eye sca…

This study follows 45 adults with severe plaque psoriasis who are starting a new standard treatment. Researchers will track changes in skin redness, scaling, and thickness, as well as features seen under a special magnifying tool called a dermoscope. They will also measure how th…

This study compares two scoring methods (REDS and qSOFA) to see which better predicts death within 30 days in emergency patients with suspected sepsis. Researchers will enroll 80 adults at Assiut University. The goal is to improve early identification of high-risk patients and gu…

This study looks at the eating habits of 50 pregnant women with inflammatory bowel disease (IBD). Researchers want to see if better diet quality leads to healthier pregnancies and baby growth. The goal is to find nutritional gaps and suggest better dietary guidelines for these mo…

This study will check if artificial intelligence (AI) can accurately predict how a person's nose will look after rhinoplasty (nose job) surgery. Researchers will compare AI-generated predictions with actual post-surgery photos using digital analysis. The study involves 20 adults …

This study will use ultrasound to measure blood flow in the brains of 200 healthy newborns, both full-term and premature. The goal is to find normal differences in blood flow based on how early a baby is born. These reference values could help doctors spot problems earlier and im…

This study looks at whether common blood tests (hs-CRP, triglycerides, and glucose) can help detect liver fibrosis in people with non-alcoholic fatty liver disease (NAFLD). Researchers will enroll 96 adults and compare these blood markers with liver scans. The goal is to find a s…

This study looks at whether a substance in the blood called catestatin can be used as a marker for disease activity in people with systemic sclerosis (scleroderma). Researchers will compare catestatin levels in 70 patients with the disease to healthy volunteers. The goal is to se…

This study looks at how intestinal parasites may cause or worsen malnutrition in children aged 2 to 15 in Assiut, Egypt. Researchers will compare 116 malnourished children with healthy ones to see how common these infections are and how they affect growth. The goal is to better u…

This study aims to find out if people with gastrointestinal angiodysplasia (abnormal blood vessels in the gut that cause bleeding) also have blood disorders, especially related to von Willebrand factor. Researchers will check if this factor can help predict the risk of rebleeding…

This study looks at whether a simple score based on routine blood tests (the CALLY index) can help predict short-term problems after emergency heart attack treatment. Researchers will follow 140 patients for 30 days to see if the score is linked to complications like heart failur…

This lab study uses urine samples from 60 people with urinary tract infections (UTIs) to see if chitosan nanoparticles (made from shrimp shells) can break down the sticky biofilms that bacteria create. The goal is to find new ways to fight stubborn infections, especially those li…

This study looks at how common muscle loss (sarcopenia) is in people with inflammatory bowel disease (IBD) using CT scans. Researchers want to see if muscle loss affects how well biologic treatments work. About 50 adults with IBD who have received biologic therapy will be include…

This study will check 138 children with congenital heart disease for chromosomal abnormalities using a blood test. Researchers want to find out how common these genetic changes are and how they relate to specific heart problems. The goal is to improve early diagnosis and help fam…

This study aims to find out if two substances in spinal fluid, called NSE and S100B, can help doctors predict how well children with encephalitis (brain swelling) will recover. Researchers will follow 90 children aged 1 month to 18 years who have symptoms like confusion, seizures…

This study surveys 300 general practitioners in Upper Egypt to find out what they know about diagnosing and treating H. pylori, a common stomach infection. The goal is to identify gaps in knowledge and barriers that prevent proper care. No treatments are given; the study simply c…

This study will compare two types of catheters used in newborns who need long-term IV access: umbilical venous catheters (UVCs) and peripherally inserted central catheters (PICCs). Researchers will track complications, how long each catheter stays in place, and rates of serious b…

This study will follow 82 children with asthma to see how other health problems (comorbidities) and specific substances in the blood affect their response to treatment. Researchers will measure lung function and look at certain microRNAs and proteins to find patterns that could h…

This study looks at Candida fungi that cause infections in patients with weakened immune systems in the hematology ICU. Researchers will collect samples from 300 patients to see how these fungi form biofilms (slimy layers that protect them) and resist antifungal medicines. The go…

This study looks at stored tumor samples from 100 people who had their bladder removed for muscle-invasive bladder cancer. Researchers want to see if the mix of cancer cells, supportive tissue, and immune cells can help predict who will do better or worse after surgery. The goal …

This study will check if blood flow inside the testicles can predict how well men recover after surgery for varicocele (enlarged veins in the scrotum). Forty infertile men will get ultrasound scans and give sperm and blood samples before and three months after surgery. The goal i…

This study looks at whether a simple calculation called the triglyceride-glucose (TyG) index can help predict insulin resistance in people who have both pre-diabetes and chronic kidney disease. Researchers will compare the TyG index with standard tests in 60 adults. If successful…

This study compares keyhole (laparoscopic) hysterectomy to open abdominal hysterectomy in women with non-cancerous gynecologic conditions, specifically in hospitals with limited resources. The main goal is to see which approach leads to a shorter hospital stay. The study will enr…

This study looks at how the size and number of ovarian follicles (fluid sacs containing eggs) on the day of the trigger shot affect how many eggs can be retrieved during an IVF cycle. Researchers will track 60 women aged 18-35 undergoing ICSI to find the smallest follicle size th…

This observational study will enroll 150 adults aged 40-70 at intermediate heart risk to see if higher levels of lipoprotein(a) in the blood are linked to more calcium in the coronary arteries, as measured by a CT scan. Participants will provide a blood sample and undergo a non-c…

This study looks at the health, nutrition, and daily living of 330 older adults (60+) in a rural Egyptian village. Researchers will interview participants and do simple physical checks to find common health problems like chronic diseases, frailty, and malnutrition. No treatments …

This study looks at how sleep disorders and problems with the body's automatic functions (like heart rate control) are connected in older adults with heart disease. Researchers will study 210 patients aged 65 and older to find out how common sleep issues are and how they affect h…

This study compares two types of temporary stomas (ileostomy vs colostomy) in 36 adults having colorectal surgery. The goal is to see which one leads to fewer serious problems like leaks from the surgical connection. Results will help surgeons choose the best option for each pati…

This study looks at whether a non-invasive device (ICON®) can reliably measure heart function in people with COPD who are in the intensive care unit. Researchers will track changes in cardiac output during the ICU stay. The goal is to see if this simple, sticker-based monitor can…

This study will measure how often sperm can be found in a single testis when men with non-obstructive azoospermia (no sperm in their semen) undergo a sperm retrieval procedure on both testicles. Researchers will also identify factors that make successful retrieval more likely. Ab…

This study will look at blood test results from 100 adults with myelodysplastic syndromes (MDS) to see if certain markers can predict how the disease will progress. Researchers will check levels of hemoglobin, albumin, lymphocytes, platelets, and other factors. The goal is to bet…

This study will follow 30 children under 18 who have surgery for a specific type of brain tumor (midline posterior fossa tumors). Researchers want to see how well children recover after surgery and what factors, like tumor type or how much was removed, affect their long-term heal…

This study looks back at the medical records of 200 women treated for gynecological cancers at Assiut University Hospital between 2022 and 2025. Researchers will measure how long patients lived after diagnosis and compare those survival rates to international standards. The goal …

This study looks at whether the ratio of two substances in the blood (CRP and albumin) can help predict acute kidney injury in people with acute pancreatitis. Researchers will follow 150 adults admitted to the hospital with pancreatitis. The goal is to find a simple, low-cost way…

This study looks back at 300 women treated for placenta accreta spectrum (a condition where the placenta grows too deeply into the womb) over the past 10 years at Assiut University Hospital. Researchers will compare different surgical methods, including womb-sparing techniques, t…

This study will look at 80 adult cancer patients getting PET/CT scans to compare different ways of measuring SUV, a key value that shows how active the cancer is. Researchers want to see if adjusting for body surface area gives more reliable results than the standard method, espe…

This study aims to see if a special heart function test (called the myocardial performance index) can help doctors better monitor and make decisions for fetuses with anemia. The study will include 15 pregnant women whose babies have anemia due to blood type incompatibility or a v…

This study looks at two surgical methods to fix severe pelvic fractures: traditional open surgery with a large cut, and a newer, less invasive method with small cuts. Researchers will review medical records of 60 adults treated between 2016 and 2024 to compare bone healing, compl…

This study will measure levels of a small molecule called microRNA-155 in 100 people who need regular blood transfusions, mostly due to beta thalassemia. The goal is to see if higher levels of this molecule are linked to the formation of antibodies that attack donor blood cells. …

This study looks at 120 adults with a mild form of underactive thyroid (subclinical hypothyroidism) to see if it changes liver enzymes and cholesterol levels. Participants will have their blood tested and compared to people with normal thyroid function. No treatment is given—the …

This study looks at a rare form of Down syndrome called translocation Down syndrome, which affects about 3-4% of children with Down syndrome. Researchers will test 230 children and their parents in Egypt to see how often this type occurs and whether parents carry a hidden genetic…

This study looks at 80 samples of a tough, drug-resistant bacteria called Pseudomonas aeruginosa. Researchers will measure how active a certain gene (mexB) is and how well the bacteria form sticky layers called biofilms. The goal is to find connections that could help develop bet…

This study aims to improve how doctors estimate a baby's weight before birth. Current methods focus on bone size and can be inaccurate, especially for very large or very small babies. Researchers will measure soft tissue thickness along with standard measurements in 300 pregnant …

This study looks at why children wet the bed and what types of bedwetting exist. Researchers will check 80 children aged 5 and older using interviews, physical exams, urine tests, and ultrasounds to find medical causes like constipation or enlarged tonsils. The goal is to help do…

This study will look at 100 people with microbial keratitis, a serious eye infection, to understand what germs cause it, who is at risk, and how patients recover. Researchers at Assiut University Hospital will collect information from patients attending the cornea clinic. The goa…

This study will survey 240 parents of children up to 2 years old who have diaper rash (napkin dermatosis). The goal is to understand what parents know about the causes, prevention, and treatment of diaper rash, and how they care for it. Researchers will also identify the most com…

This study observes 30 adults on a heart-lung machine (VA-ECMO) for severe heart failure. Researchers will measure brain oxygen levels and compare them with blood flow and heart function data. The goal is to understand how these factors relate, which may help improve monitoring a…

This study looks at how a class of diabetes drugs called SGLT2 inhibitors might change the structure of the heart's left atrium in people with type 2 diabetes. Researchers will use ultrasound to measure heart function before and after 6 months of treatment. The goal is to underst…

This study will follow 300 premature babies born before 34 weeks and weighing under 1500 grams to see how often they develop bleeding in the brain (intraventricular hemorrhage). Researchers will look for risk factors in both mothers and babies and track short-term outcomes like d…

This study looks at how many people with knee osteoarthritis also have sarcopenia, a condition where muscles become weak and shrink. Researchers will check muscle mass, strength, and physical performance in 224 adults aged 40 and older in Upper Egypt. The goal is to better unders…

This study looks at whether changes in blood sugar levels before giving antibiotics can help predict how serious sepsis will be and what outcomes patients in the ICU will have. Researchers will monitor 105 adults with sepsis, tracking their glucose levels and a new measure called…

This study looks at the bacteria causing deep neck infections in 50 adults. Researchers will compare lab results with how patients recover, including hospital stay length and complications. The goal is to learn which antibiotics work best and to improve future treatment guideline…

This study uses ultrasound to measure the distance between the Achilles tendon and important nerves and blood vessels in babies aged 1-6 months with clubfoot in one foot. The goal is to compare these measurements between the clubfoot and the normal foot. This information may help…

This study looks at how a small ligament in the hip joint affects treatment for developmental hip dysplasia (DDH) in children. Researchers will study 50 children who need surgery after other treatments failed. The goal is to learn if this ligament helps guide better surgical choi…

This study looks at whether measuring the baby's liver length and volume with ultrasound can help doctors understand how gestational diabetes affects the baby. Researchers will compare these measurements between pregnant women with and without diabetes. The goal is to find a simp…

This study aims to find out how many people in Assiut Governorate, Egypt, have schistosomiasis (a parasitic infection) and what factors increase their risk. Researchers will test urine and stool samples from 359 people aged 5 and older using a microscope. The goal is to better un…

This study looks at a simple blood test called the triglycerides glucose index in people with type 2 diabetes. Researchers want to see if this index is linked to long-term complications like eye, kidney, or nerve damage. About 200 adults aged 18 to 65 will be followed over time. …

This study compares two methods—ultrasound of the inferior vena cava and central venous pressure monitoring—to see which better predicts fluid needs in patients with septic shock. Researchers will enroll 70 adults in the emergency department to evaluate accuracy. The goal is to i…

This study will compare two methods (STUMBL and TTSS) for predicting serious complications and death in people with blunt chest trauma, such as from a car crash or fall. Researchers will enroll 124 adults and track who develops pneumonia, needs a breathing machine, or dies. The g…

This study follows 50 people with a serious spinal infection (spondylodiscitis) for one year to see how well standard treatments like antibiotics and braces work. Researchers will check cure rates, pain levels, and daily function using tests and scans. The goal is to better under…

This study asks 420 pregnant women in their last trimester about their use of medicines without a doctor's advice. Researchers want to learn how common self-medication is and what drives it. The goal is to find gaps in knowledge and create better safety education for mothers.

This study looks at whether measuring belly fat with CT scans can help predict how well biologic therapy works for people with ulcerative colitis. Researchers will follow 200 adults for 6 months to see if changes in fat tissue relate to treatment response. The goal is to find a b…

This study looks at whether changes in blood flow in the finger and arm can quickly tell doctors if a nerve block has numbed the arm for surgery. Fifty adults having upper limb surgery will be monitored. The goal is to find a faster, more reliable way to confirm the block is work…

This study looks at whether frailty can help predict bleeding in older adults (65+) who have had a heart attack or unstable angina. Researchers will follow 850 patients for up to 6 months to see if adding frailty to standard risk tools improves bleeding predictions. The goal is t…

This study looks at whether having a baby soon after a previous C-section increases the chance of problems like heavy bleeding or organ injury during the next C-section. Researchers will follow 80 pregnant women with one prior C-section. The goal is to help women and doctors plan…

This study aims to see if a new scoring system (the Mansoura score) can accurately predict a serious infection called spontaneous bacterial peritonitis (SBP) in people with liver cirrhosis and fluid buildup in the belly. Researchers will enroll 250 adults with cirrhosis and ascit…

This study will measure levels of a specific thyroid antibody (anti-thyroglobulin) in 112 adults with diabetes. The goal is to better understand how often thyroid autoimmunity occurs in people with diabetes. Participants will provide a blood sample, and those with a history of th…

This study will survey 500 non-medical adults in Upper Egypt to find out what they know about H. pylori infection, including how it spreads, how it is diagnosed, and what complications it can cause. The goal is to identify gaps in knowledge, attitudes toward testing and treatment…

This study will look at 300 adults who had a stroke caused by a blood clot and arrived at Assiut University Hospitals within 24 hours. Researchers want to find out how many of these strokes are due to a blockage in a large brain artery. They will also describe the patients' featu…

This study will check if two blood test measures (MPV and PDW) can help doctors detect deep vein thrombosis (DVT) early in ICU patients who are on breathing machines. Researchers will follow 100 adults in the ICU and use ultrasound to confirm any clots. The goal is to find a simp…

This study aims to learn how often liver cancer (HCC) ruptures, what raises the risk, and how long people live after it happens. Researchers will review records of 100 patients with a ruptured liver tumor. The goal is to find patterns that could help predict and manage this dange…

This study aims to find what factors help predict recovery in children with acute disseminated encephalomyelitis (ADEM), a rare brain inflammation. Researchers will follow 25 children aged 6 months to 18 years, tracking their recovery using a disability scale. The goal is to bett…

This study uses CT scans to measure how a deviated nasal septum (a crooked wall inside the nose) affects the size of the maxillary sinuses and the risk of sinus infections. Researchers will compare the sinus on the crooked side to the other side in 120 adults. No treatment is giv…

This study looks at how long-acting reversible contraception (LARC) affects women's quality of life. Researchers will compare women using LARC methods (like IUDs or implants) with those using other birth control. About 427 women aged 18 to 45 will complete a questionnaire about t…

This study looks at how children with a large hole in the heart (VSD) grow after surgery to close it. Researchers will measure weight, height, and BMI before and after the procedure to see when kids reach normal growth levels. About 58 children under 2 years old will take part. T…

This study will follow 500 people having a major heart attack (STEMI) to see how the time from first symptoms to opening the blocked artery affects the heart's electrical signals. Researchers will check if longer delays lead to more dangerous heart rhythms and other complications…

This study will test whether a scoring tool called BIND can help doctors spot early signs of brain injury in newborns with severe jaundice. Researchers will evaluate 80 infants under 28 days old who need intensive light therapy. The goal is to see if the BIND score can predict wh…

This study will check if certain blood platelet measurements can show how active inflammatory bowel disease (IBD) is. Researchers will compare platelet levels with standard disease activity scores in 84 adults with IBD. The goal is to see if these easy-to-get blood tests could he…

This study will compare two different ways of using a breathing machine during laparoscopic abdominal cancer surgery. The goal is to see which method is better for the patient's heart function and lung health. Sixty adults aged 20-80 will take part. The results may help doctors c…

This study looks at whether high uric acid levels (hyperuricemia) are linked to fatty liver disease and liver scarring in 111 obese adults. Researchers aim to understand this connection to help catch liver problems early and guide future treatments. Participants must be 18-65 yea…

This study aims to see if common blood tests can help predict how severe a heart attack is and what the recovery might look like, especially for people with diabetes. Researchers will follow 1,000 patients who have a specific type of heart attack (STEMI) and are treated with a pr…

This study aims to see if MRI scans can accurately measure the size of breast tumors compared to the actual tumor removed during surgery. About 59 women with suspicious or cancerous breast masses will get an MRI before surgery. Researchers will compare the MRI-based 3D volume to …

This study will enroll 80 adults in the emergency department who are in shock (very low blood pressure). Researchers will compare two methods to detect low blood volume: an ultrasound of a large vein in the belly versus a standard pressure monitor placed near the heart. The goal …

This study aims to find out how often hemolytic uremic syndrome (HUS) occurs in children admitted to Assiut University Children's Hospital. Researchers will look at medical records of 50 children under 18 with confirmed HUS to describe their symptoms and lab results. The study do…

This study looks at whether a protein in the blood called uromodulin can help predict how well the kidneys will recover in adults with sepsis-related acute kidney injury. Researchers will measure uromodulin levels at the start, after one week, and at hospital discharge in 30 pati…

This study looks at children with joint problems that are not caused by inflammation, such as stiffness or deformity. The goal is to find the real underlying causes using exams, lab tests, and imaging. By better understanding these conditions, doctors hope to avoid misdiagnosis a…

This study uses safe, non-invasive ultrasound to measure pelvic floor changes in women who have given birth. Researchers will compare women who had vaginal deliveries with those who had C-sections to understand differences in pelvic support. Participants fill out a short question…

This study will test new scoring systems to see if they can better predict serious complications and death in people hospitalized with liver cirrhosis. Researchers will compare these new scores to standard ones in 100 adult patients. The goal is to identify high-risk patients mor…

This study looks at why fluid builds up around the lungs in people with advanced chronic kidney disease (stages 3 to 5). Researchers will collect a small sample of chest fluid and blood from 100 adults to compare different diagnostic methods. The goal is to find the most accurate…

This study looks at whether low vitamin D levels are linked to more active disease in people with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers will measure vitamin D in the blood of 100 adults with IBD and compare it to their cur…

This study looks at how to best measure the energy needs of critically ill patients in the ICU. Researchers will use a special device called indirect calorimetry to get accurate readings and compare them to standard formulas. The goal is to improve nutritional support for these p…

This study will check if people with lupus nephritis (kidney inflammation caused by lupus) have low zinc levels in their blood. Researchers will look at 75 patients to see if low zinc is connected to worse kidney function. The goal is to better understand the disease, not to test…

This study will check 106 infants under 2 years old who have cholestasis (a liver condition) to see how many also have congenital heart defects. Researchers will use echocardiograms and developmental tests to understand the link. No treatment is given—the goal is to learn more ab…

This study looks at 100 men with varicoceles in both testicles to see if the amount of backward blood flow affects sperm health. Researchers will measure blood flow and sperm concentration before and 3 months after varicocele repair surgery. The goal is to learn which patients be…

This study will survey 350 married women aged 18-49 in Assiut, Egypt to learn what they know and think about different family planning methods, and which ones they actually use. Researchers will also explore social and economic reasons that affect their choices. The goal is to pr…

This study looks at 88 first-time mothers to see which method—a doctor's exam (Bishop score) or an ultrasound—better predicts if labor induction will lead to a vaginal birth within 24 hours. Participants are full-term pregnant women with a single baby in head-down position. The g…

This study will measure fat, muscle, and bone mass in 115 children aged 5-18 with beta thalassemia major who receive regular blood transfusions. Researchers will use a simple, non-invasive tool (bioelectrical impedance) to see how transfusion frequency, iron levels, nutrition, an…

This study looks at 72 adults with rheumatoid arthritis to see if simple blood tests and ultrasound scans can better track how well treatments are working. Researchers will compare patients taking JAK inhibitors with those on standard therapies. The goal is to find easier, more a…

This study will watch and record information from 120 newborns with serious stomach or gut problems. The goal is to learn which emergencies are most common and what affects their recovery. No new treatments are tested; the study only collects data to improve future care.

This study looks at whether a common stomach infection called H. pylori is more common in women who have had two or more miscarriages for no known reason. Researchers will test 100 women for the infection and compare results. The goal is to see if there is a link, not to provide …

This study will examine 100 adults with low platelet counts to see how many have an enlarged spleen. Researchers want to learn if spleen size is linked to different symptoms, complications, or how well patients respond to treatment. The goal is to better understand the role of th…

This study uses CT scans to see if the shape and angle of the eustachian tube (the small passage connecting the ear to the throat) are linked to pressure inside the middle ear. Researchers will measure these features in 50 healthy people aged 7 and older. The goal is to better un…

This study looks at 96 adults with lower back pain to see if the damage shown on an MRI matches how much pain they actually feel. Participants will answer pain and disability questionnaires and have a physical exam. Researchers will compare these results with their MRI scans to h…

This study looks at whether H. pylori stomach infections are linked to psychological symptoms like anxiety or depression. Researchers will study 130 patients diagnosed with H. pylori-related gastritis to measure mental health symptoms and see if treating the infection improves mo…

This study will check if a common stomach infection (H. pylori) is linked to how active lupus is in patients. About 115 adults with lupus will be tested for H. pylori using a stool test, and their lupus activity will be measured. The goal is to see if there is a connection, which…

This study will track 200 children admitted to the pediatric intensive care unit to see how imbalances in minerals like sodium, potassium, and calcium relate to their chances of survival. The goal is to find patterns that could help doctors identify high-risk children early and i…

This study looks at vitamin D levels in 63 critically ill children (1 month to 12 years) admitted to the ICU with severe breathing infections. Researchers will measure vitamin D in the first 24 hours and check if low levels are linked to more severe illness or higher risk of deat…

This study compares two surgical methods—laparoscopy (minimally invasive) and laparotomy (open surgery)—for treating early-stage endometrial cancer in places with limited resources. About 116 participants will be assigned to one of the two procedures to see which leads to shorter…

This study will look at how care before reaching the hospital—like knowing stroke symptoms, calling an ambulance, and transport—affects the recovery of 125 adults with confirmed stroke. Researchers will test stroke knowledge using a questionnaire. The goal is to find gaps in preh…

This study will follow 70 adults who come to Al-Rajhi University Hospital with bright red or maroon blood in their stool. Researchers want to learn what causes the bleeding, how serious it is, and what happens to patients afterward. No new treatments are being tested; the goal is…

This study looks at two proteins, CD85d and CD305, that help some B-cell cancers hide from the immune system. Researchers will measure these proteins in 180 newly diagnosed patients to see if they can predict how fast the cancer grows or how well treatments might work. The goal i…

This study will enroll 66 adults with liver cancer (hepatocellular carcinoma) who are scheduled for either transarterial chemoembolization (TACE) or microwave ablation (MWA). Researchers will use CT scans to measure tumor volume before and after treatment to see if this method ca…

This study looks at past cases of children with retinoblastoma, a rare eye cancer, to see how well three treatments—radioactive plaque, freezing therapy, and laser therapy—worked after initial chemotherapy. Researchers will review records of 150 patients treated in Egypt to find …

This study looks at whether high uric acid levels can help predict if kidney disease gets worse in people with prediabetes. Researchers will follow 150 adults with prediabetes and early-stage kidney disease for changes in kidney function. The goal is to find a simple way to ident…

This study looks at hormone changes in children aged 5 to 18 with simple obesity (caused by eating more calories than the body uses). Researchers will measure levels of hormones like insulin, leptin, and cortisol to see how often imbalances occur. No treatment is given—the goal i…

This study will use 2D and 3D ultrasound to measure vaginal laxity and bladder neck descent in 150 women who have given birth. The goal is to better understand how childbirth affects the pelvic floor. Participants will not receive any treatment, only observation and imaging.

This study checks for hormone problems in 30 children aged 3-18 with Wilson's disease. Researchers will measure how the disease affects glands like the thyroid and pituitary. The goal is to find and classify these hormone issues to improve care.

This study will track menstrual cycles in 110 teenage girls (ages 10-18) with and without diabetes to see how diabetes affects period regularity. Researchers will also check if blood sugar control and body weight are linked to menstrual problems. The goal is to better understand …

This study looks at vitamin D levels in 84 adults recently diagnosed with immune thrombocytopenia (ITP), a condition that causes easy bruising and bleeding. Researchers want to see if vitamin D levels are linked to how well patients respond to standard steroid treatment. The goal…

This study looks at a lesser-known bacteria called Providencia that can cause urinary tract infections (UTIs). Researchers will collect samples from 241 patients to identify these bacteria, test which antibiotics work against them, and find out what makes them resistant to drugs.…

This study looks at whether a non-invasive small bowel ultrasound combined with a blood test for tissue transglutaminase (tTG) antibodies can accurately measure celiac disease activity. Researchers will enroll 140 people aged 2 and older, including newly diagnosed patients, those…

This study aims to understand prediabetes in young adults and how it relates to other health issues like insulin resistance, high cholesterol, and fatty liver. Researchers will study 120 people with prediabetes at Assiut University Hospital through exams and lab tests. The goal i…

This study will follow 200 children with epilepsy to find out why some don't respond to standard seizure medicines. Researchers will look at brain scans, EEG patterns, and medical history to spot early clues. The goal is to identify resistant cases sooner and explore alternative …

This study looks at how often people develop a new fatty liver disease (MASLD) after receiving a liver transplant. Researchers will follow 100 adults who had a liver transplant for reasons other than MASLD. The goal is to find out how common this condition is and what factors, li…

This study will check how certain leukemia drugs (tyrosine kinase inhibitors) affect blood sugar and cholesterol levels in people with chronic myeloid leukemia. Researchers will measure changes in HbA1c and lipid profiles over time. The goal is to understand these side effects be…

This study aims to find a simpler and reliable way to detect colistin resistance in multidrug-resistant bacteria. Researchers will collect 90 samples from hospitalized patients and compare a disk elution test with the standard method. They will also look for the genes that cause …

This study will measure two immune system markers, CD274 and CD276, in blood and bone marrow samples from 159 people newly diagnosed with B-cell cancers like leukemia and lymphoma. The goal is to see if these markers can help doctors better diagnose these cancers and understand w…

This study looks at how often obsessive-compulsive symptoms occur in adults with substance use disorder compared to similar people without it. Researchers will interview 102 participants aged 18-50 and use standard questionnaires to measure symptoms, addiction severity, and quali…

This study looks at whether a simple, painless ultrasound can predict the risk of dangerous bleeding from enlarged veins in the esophagus (varices) in people with liver cirrhosis. Researchers will measure spleen size and a key vein's width on ultrasound and compare those results …

This study looks at why some people with crossed or wandering eyes (strabismus) need a second surgery after the first one. Researchers will follow 62 patients who are having repeat surgery to find out which factors make a second operation more likely and how successful the repeat…

This study aims to find out how common heavy menstrual bleeding is among female students at Assiut University in Egypt and how it affects their daily life and school performance. Researchers will survey 340 students and also check their blood for signs of anemia. The goal is to b…

This study compares blood tests from 200 adults with type 2 diabetes and healthy volunteers to see if platelet size and activity are linked to inflammation and blood sugar control. Participants give one blood sample during a routine clinic visit. No treatments or follow-up are in…

This study will track weight and body mass index (BMI) changes in 50 people with inflammatory bowel disease (IBD) who are being treated with biologic drugs. Researchers want to see if weight gain leads to higher drug doses and increased treatment costs. The goal is to understand …

This study aims to find out how often people with scleroderma have high blood pressure in their lungs (pulmonary hypertension). Researchers will use a heart ultrasound (echocardiography) to screen 35 adults with confirmed scleroderma. The goal is to detect this serious condition …

This study looks at how markers of inflammation (like hs-CRP and neutrophil-to-lymphocyte ratio) and heart damage (troponin) are related to heart function in people with acute coronary syndrome. Researchers will measure these markers and use advanced ultrasound to check heart fun…

This study follows 120 adults who had a stroke and a procedure to remove a blood clot from a large brain artery. Researchers want to find out why some people develop problems with memory, attention, or thinking afterward. Participants will take thinking tests and mood surveys at …

This study looks at 32 children with a first episode of ADEM, a rare brain and spinal cord inflammation that often follows a virus. Researchers will check early MRI scans and spinal fluid samples to see if they can predict which children will recover fully and which might have la…

This study looks at adults with intussusception, a condition where part of the intestine slides into another part, causing a blockage. Researchers want to find out how often the cause is harmless (like a benign growth) versus cancer. They will also check how well CT scans predict…

This study looks at how the bacteria in your gut might influence heart recovery after a heart attack procedure called primary PCI. Researchers will measure a substance called TMAO, made by gut bacteria, in 144 adults before and after the procedure. The goal is to understand if gu…

This study looks at children with chronic abdominal pain (lasting 3 months or more) to see how often an upper endoscopy—a camera test that looks inside the stomach—finds a medical cause. About 130 children aged 18 or younger will be included. The goal is to help doctors decide wh…

This study will enroll 70 pregnant women to test a new ultrasound scoring system that combines standard amniotic fluid measurements with fetal bladder size and appearance. The goal is to see if this combined method can more accurately detect too little or too much amniotic fluid.…

This study examines tissue samples from 50 women with type 1 endometrial cancer to measure levels of a protein called METTL-14. Researchers want to see if higher or lower amounts of this protein are linked to tumor features and patient survival. The goal is to better understand w…

This study looks at how obesity and gastroesophageal reflux disease (GERD) are connected. Researchers will measure how common obesity is among 200 adults with GERD. The goal is to better understand the link between these two conditions.

This study will look at 80 children with Guillain-Barré syndrome to find out which factors help predict a full recovery within 3 months. Researchers will track symptoms and test results to build better prediction tools. The goal is to improve treatment and care for young patients…

This study looks at how well doctors follow infection prevention steps before, during, and after C-sections. It will track 105 women for 30 days after surgery to see how many get an infection. The goal is to find out if following the rules helps reduce infections and improve reco…

This study examines tissue samples from 100 bladder cancer patients to see if two microscopic features—how deep early tumors invade and small cell clusters at the tumor edge—can predict cancer return, spread, or survival. Researchers will review past medical records and lab slide…

This study will check if a new scoring system called STARZ can predict kidney injury in newborns within the first week of life. Researchers will enroll 140 babies in the NICU and compare the STARZ score to standard tests. The goal is to catch kidney problems early so doctors can …

This study looks at whether teenagers aged 15-19 in Beni Adi village, Egypt, have their rights fulfilled in health, education, protection, and community involvement. Researchers will interview 300 teens to check things like school attendance, access to healthcare, and safety from…

This study looks at whether anemia (low red blood cells) can help predict how Inflammatory Bowel Disease (IBD) will progress in patients. Researchers will track 83 adults with IBD at Assiut University Hospitals to see if those with anemia have higher hospitalization rates. The go…

This study will check how often people have trouble with memory, attention, and other thinking skills after a stroke. Researchers will evaluate 400 adults aged 18 to 60 who had their first stroke within the last 3 months. The goal is to understand how common these problems are, n…

This study will look at how often children with sickle cell disease have painful vaso-occlusive crises and what problems arise from them. Researchers will review medical records of 25 children aged 1-18 to find risk factors and complications like acute chest syndrome or stroke. T…

This study looks at 70 children and teens with juvenile lupus to see if they have early signs of heart disease. Researchers will use ultrasound to measure the thickness of the carotid artery wall and compare it to healthy children. The goal is to understand how lupus and its trea…

This study tests whether a bedside lung ultrasound can help doctors see how well collapsed lung areas reopen in obese patients on breathing machines. About 45 adults with a BMI of 33 or higher will be scanned before, during, and after a standard lung-opening procedure. The goal i…

This study aims to understand the relationship between metabolic syndrome (a cluster of conditions like high blood pressure and excess body fat) and gastroesophageal reflux disease (GERD), commonly known as acid reflux. Researchers will observe 50 adult patients with metabolic sy…

This study aims to find a better blood test to detect active kidney inflammation in people with lupus nephritis. Researchers will measure a specific antibody in the blood of 96 participants and compare it to results from kidney biopsies. The goal is to develop a less invasive way…