Could high uric acid warn of liver damage in obesity?
NCT ID NCT07168551
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This study will examine the connection between high uric acid levels (hyperuricemia) and non-alcoholic fatty liver disease (NAFLD) in 111 obese adults. Researchers will use blood tests, ultrasound, and FibroScan to measure uric acid, liver fat, and liver scarring. The goal is to see if high uric acid can help spot liver problems early, potentially leading to better prevention strategies.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If the link is confirmed, it could point to using uric acid levels as an early warning sign for liver damage in obese adults.
- What could go wrong
- This is an observational study, not a treatment trial. It will not test any therapy, so it cannot prove that lowering uric acid prevents liver disease.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 111 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult obese patients
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age: Adults (typically 18-65 years old) 2 - Body Mass Index (BMI): Obese patients with a BMI ≥ 30 kg/m² 3- Hyperuricemia : Elevated serum uric acid levels (typically \> 7 mg/dL for men and \> 6 mg/dL for women) Exclusion Criteria: * excessive alcohol consumption ( \> 20 gm /day in men and 10 in g /day in women ) 2- use of steatogenic within the past 6 months 3- positive test for hepatitis B surface antigen and hepatitis B core antibody 4- Drug induced liver injury and autoimmune hepatitis 5 - cirrhosis and other causes of liver disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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