Assiut University
Clinical trials sponsored by Assiut University, explained in plain language.
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Heart surgery showdown: which solution protects better?
Disease control CompletedThis study tested two different solutions used to protect the heart during bypass surgery. 124 adults having coronary artery bypass grafting received either a modified Del Nido solution or an HTK solution. The main goal was to see which solution led to fewer abnormal heart rhythm…
Phase: PHASE3 • Sponsor: Assiut University • Aim: Disease control
Last updated May 26, 2026 08:00 UTC
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Muscle relaxants vs. sedation: which helps severe COVID-19 lung patients breathe better?
Disease control CompletedThis study looked at 40 severely ill COVID-19 patients with lung failure who needed a breathing machine. Researchers compared giving muscle relaxants plus sedation versus sedation alone to see which improved oxygen levels better. The goal was to find better ways to manage breathi…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 26, 2026 07:58 UTC
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Which blood pressure drug saves kidneys in pre-eclampsia?
Disease control CompletedThis study tested two blood pressure medicines, phentolamine and glyceryl trinitrate (GTN), in 170 women with severe pre-eclampsia in the ICU. The goal was to see which drug better protects kidney function. Pre-eclampsia can harm the kidneys, and GTN has been linked to kidney inj…
Phase: PHASE4 • Sponsor: Assiut University • Aim: Disease control
Last updated May 26, 2026 07:50 UTC
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Mesh may slash hernia risk after stoma reversal surgery
Disease control CompletedThis study tested whether using a mesh patch to reinforce the surgical site during stoma reversal reduces the chance of developing a hernia, infection, or pain compared to standard closure. 62 adults with temporary stomas took part. The goal is to find a better way to close the s…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 26, 2026 07:27 UTC
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Heart drug showdown: which works better during bypass surgery?
Disease control CompletedThis study compared two drugs, levosimendan and adrenaline, given during heart bypass surgery to 60 patients with weak hearts (ejection fraction 30-40%). The goal was to see which drug better supports heart function during and right after surgery. Researchers measured heart pumpi…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 18, 2026 11:58 UTC
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Titanium mesh vs. bone graft: which fixes eye socket fractures better?
Disease control CompletedThis study looked at 80 people who had a broken eye socket bone (orbital floor) after an injury like a car accident or sports impact. Doctors compared two surgical repair methods: using a titanium mesh or a piece of the patient's own hip bone. The goal was to see which method bet…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Nerve block breakthrough could prevent brain damage after trauma
Disease control CompletedThis study tested two types of nerve blocks (superior cervical sympathetic block and stellate ganglion block) to treat dangerous artery spasms in the brain after a traumatic head bleed. 60 adults aged 18-65 with refractory post-traumatic subarachnoid hemorrhage were enrolled. The…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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Simple blood test could spot IBD earlier
Diagnosis CompletedThis study looked for new blood markers to help diagnose inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers measured four specific proteins in 70 newly diagnosed patients before and after treatment. The goal was to find a simple, nonin…
Sponsor: Assiut University • Aim: Diagnosis
Last updated May 26, 2026 07:59 UTC
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Nerve block may stop shingles pain from becoming chronic
Prevention CompletedThis study tested whether a targeted nerve block, using a numbing medicine and a steroid, could prevent the long-term nerve pain that sometimes follows a shingles outbreak. One hundred adults with shingles on their chest or back received either standard care or standard care plus…
Phase: PHASE3 • Sponsor: Assiut University • Aim: Prevention
Last updated May 15, 2026 11:54 UTC
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Which drug stops early labor better? new study reveals
Symptom relief CompletedThis study tested two medicines, nifedipine and magnesium sulfate, to see which one works better at delaying preterm labor in pregnant women between 32 and 36 weeks. The goal was to postpone delivery for at least 48 hours to allow steroids to help the baby's lungs mature. The tri…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:59 UTC
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Which nerve block wins for knee surgery pain? new study compares two methods
Symptom relief CompletedThis study looked at two different nerve block techniques to manage pain after knee arthroscopy (a type of keyhole knee surgery). Fifty adults aged 20-60 were enrolled to compare an ultrasound-guided genicular nerve block with an IPACK block. The goal was to see which method prov…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:56 UTC
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New pain block helps kids recover from hip surgery
Symptom relief CompletedThis study tested whether an ultrasound-guided erector spinae muscle block can reduce pain after hip reconstruction surgery in children aged 2-7. Seventy children received the block along with general anesthesia. Researchers measured pain levels, time to first painkiller request,…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:56 UTC
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Pre-Surgery prep cuts recovery trouble for gynecologic cancer patients
Symptom relief CompletedThis study tested a 'prehabilitation' program—exercise, nutrition, and education before surgery—for 140 women with gynecologic cancer. The goal was to see if it reduces complications, pain, and hospital stays after surgery compared to standard care. Results are not yet reported.…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:55 UTC
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New pain relief combo tested for cancer surgery recovery
Symptom relief CompletedThis study tested whether adding dexmedetomidine to a standard numbing medicine (bupivacaine) improves pain relief after major lower abdominal cancer surgery. Researchers compared two types of nerve blocks: quadratus lumborum block and epidural block. 54 adults aged 18-70 partici…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:55 UTC
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New combo may stop morphine side effects in c-sections
Symptom relief CompletedThis study looked at whether adding dexamethasone and atropine to spinal anesthesia can prevent nausea and vomiting caused by morphine in women having planned C-sections. 150 women aged 18-45 took part. The goal was to see if these drugs could reduce the need for extra anti-nause…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:55 UTC
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New cataract technique cuts ultrasound time for brown cataracts
Symptom relief CompletedThis study tested a small change in cataract surgery for people with brown cataracts, a dense type that usually needs more ultrasound energy to break up. Surgeons created a groove in the lens and then rinsed it with saline for 30 seconds before using ultrasound. The goal was to s…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:54 UTC
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Nutrition support eases radiation side effects in head and neck cancer patients
Symptom relief CompletedThis study looked at whether active nutritional support can lower the chance of painful mouth sores (mucositis) and improve quality of life in people with head and neck cancer who are getting radiation therapy. 47 newly diagnosed adults took part. Researchers tracked weight and b…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:52 UTC
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Magnesium mist may soothe sore throat after surgery
Symptom relief CompletedThis study tested whether inhaling a magnesium sulfate mist before a breathing tube is placed can reduce sore throat and stress after surgery. One hundred adults having gallbladder surgery took part. The goal was to see if this simple treatment could make recovery more comfortabl…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:52 UTC
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New throat pack method aims to soothe post-surgery pain
Symptom relief CompletedThis study tested whether using throat packs soaked in a steroid drug (dexamethasone) can reduce sore throat after septoplasty, a type of nose surgery. 65 adults took part. The goal was to see if this simple change could make recovery more comfortable.
Phase: PHASE3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:51 UTC
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Antidepressant shows promise for easing Post-Surgery pain in breast cancer patients
Symptom relief CompletedThis study tested whether giving the antidepressant mirtazapine before and after mastectomy surgery can lower pain and the need for strong painkillers like morphine. Sixty-two women scheduled for mastectomy took part. Researchers measured pain levels and morphine use in the first…
Phase: EARLY_PHASE1 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:50 UTC
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New study tests better pain control after cesarean delivery
Symptom relief CompletedThis study tested whether adding magnesium sulfate or neostigmine to a standard numbing medicine (bupivacaine) in a belly-wall nerve block could improve pain control after C-section. Sixty-eight women having planned cesarean deliveries under spinal anesthesia took part. The goal …
Phase: PHASE2, PHASE3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:49 UTC
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New study tests safer pain relief for gallbladder surgery
Symptom relief CompletedThis study tested two different non-opioid pain medicines given continuously during gallbladder surgery to see which one controls pain better and reduces the need for opioids. 64 adults having laparoscopic gallbladder removal took part. The goal was to find a safer way to manage …
Phase: PHASE4 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:48 UTC
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New combo may ease Post-Surgery pain for gallbladder patients
Symptom relief CompletedThis study tested whether adding magnesium sulfate or dexmedetomidine to a standard numbing medicine (bupivacaine) improves pain control after laparoscopic gallbladder removal. 63 adults undergoing surgery received one of three combinations via a nerve block. The goal was to see …
Phase: PHASE4 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:27 UTC
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Could magnesium make mastectomy recovery less painful?
Symptom relief CompletedThis study looked at whether adding magnesium sulfate to a standard nerve block (erector spinae plane block) can reduce pain and the need for morphine after a mastectomy. Sixty women having breast cancer surgery took part. The main goal was to see how much morphine they needed in…
Phase: EARLY_PHASE1 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:27 UTC
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Which nerve block wins for hernia pain? study reveals answer
Symptom relief CompletedThis study tested two different ultrasound-guided nerve blocks to see which one provides better pain relief after inguinal hernia repair. Forty-three men undergoing hernia surgery received one of the two blocks, and their pain was measured using a simple 0-to-10 scale. The goal w…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 26, 2026 07:24 UTC
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Injection or voice lessons? new study tests best fix for sore throats from vocal nodules
Symptom relief CompletedThis study tested two treatments for vocal nodules (non-cancerous growths on the vocal cords caused by voice overuse) in 50 adult women. One group received a steroid injection directly into the nodule, while the other group underwent a special voice therapy technique called the A…
Phase: PHASE4 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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New nerve block technique may help hip surgery patients move sooner
Symptom relief CompletedThis study tested two different nerve block approaches to control pain after hip fracture surgery. 96 adults with hip fractures received either a PENG block plus lateral femoral cutaneous nerve block or a supra-inguinal fascia iliaca compartment block. The goal was to see which m…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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Which drug stops Post-C-Section shivers best?
Symptom relief CompletedThis study tested two medicines, dexamethasone and dexmedetomidine, to see which one better prevents shivering after a C-section done with spinal anesthesia. 382 women took part. The goal was to find a safe way to keep new mothers comfortable after surgery.
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Which kidney stone surgery is better? new study compares two options
Symptom relief CompletedThis study compared two common, minimally invasive surgeries for removing kidney stones that are 2 cm or smaller: flexible ureteroscopy (f-URS) and mini-percutaneous nephrolithotomy (mini-PCNL). Researchers wanted to see which method clears stones more completely and has fewer si…
Sponsor: Assiut University • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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New study tests drug to calm kids after cleft palate surgery
Symptom relief CompletedThis study tested whether a single dose of dexmedetomidine, given during surgery, can prevent agitation in children aged 1-7 years after cleft palate repair. Sixty children were randomly assigned to receive either the drug or a placebo (saline). The main goal was to measure emerg…
Phase: PHASE3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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New recovery plan cuts hospital time for thyroid surgery patients
Symptom relief CompletedThis study tested a program called ERAS (Enhanced Recovery After Surgery) for people having their thyroid gland removed. The goal was to see if it could reduce pain, nausea, and time spent in the hospital. 143 adults took part, and their results were compared to a group that had …
Sponsor: Assiut University • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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New combo may cut opioid use for cancer pain
Symptom relief CompletedThis study tested whether adding duloxetine (a nerve pain drug) to tramadol (a painkiller) helps people with chronic cancer pain use less tramadol. 400 adults with cancer pain who had not taken painkillers before took part. Half received duloxetine plus tramadol, the other half a…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 22, 2026 13:51 UTC
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Can ketamine or magnesium beat morphine after breast surgery?
Symptom relief CompletedThis study tested whether adding ketamine or magnesium sulfate to a standard numbing injection (nerve block) could better control pain after breast cancer surgery. Sixty adults undergoing mastectomy received one of the two add-ons, and researchers measured how much extra morphine…
Phase: PHASE2 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Which pain block lasts longest after keyhole lung surgery?
Symptom relief CompletedThis study tested three different pain-relief methods for people having lung surgery through a single small cut. 102 adults were randomly assigned to receive one of the blocks. The goal was to see which method kept patients comfortable the longest after surgery.
Phase: PHASE2 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 19, 2026 12:01 UTC
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Laser showdown: which eye surgery fixes mixed astigmatism best?
Symptom relief CompletedThis study compared two types of laser eye surgery for people with mixed astigmatism, a condition where the eye focuses light unevenly. 39 adults received either femtosecond laser-assisted LASIK or single-step transepithelial photorefractive keratectomy. The goal was to see which…
Sponsor: Assiut University • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Virtual reality goggles ease Kids' dental dread in new study
Symptom relief CompletedThis study tested whether wearing augmented reality goggles during a tooth extraction could help children aged 6 to 10 feel less pain and anxiety. Sixty kids were split into two groups: one used the goggles as a distraction, while the other received standard care. Researchers mea…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 14, 2026 12:05 UTC
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Newer nerve block may ease broken rib pain with fewer risks
Symptom relief CompletedThis study compared two types of nerve blocks for pain relief in 60 adults with multiple broken ribs. One is a newer, easier technique called retrolaminar block (RLB), and the other is the standard paravertebral block (PVB). The goal was to see which provides better pain control …
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 12, 2026 13:39 UTC
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Stomach bug study reveals antibiotic weaknesses
Knowledge-focused CompletedThis study looked at 100 adults with H. pylori infection to understand why some treatments fail. Researchers tested stomach biopsies to find which antibiotics work best and which resistance genes are present. The goal was to learn how diet, medications, and bacterial genetics aff…
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 26, 2026 08:00 UTC
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Blood clues: simple tests may forecast myeloma survival
Knowledge-focused CompletedThis study looked at whether certain blood test results (blood thickness, protein ratios, and red blood cell size variation) can help predict how well people with newly diagnosed multiple myeloma will do over the next year. Researchers followed 48 patients to see if these simple …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 26, 2026 07:59 UTC
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New C-Section technique could reduce injury in repeat births
Knowledge-focused CompletedThis study tested a new technique called 'external pop out' for delivering the baby's head during repeat C-sections, comparing it to the standard method. It involved 600 women having an elective repeat C-section. The goal was to see if the new method is safer and reduces injury t…
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 26, 2026 07:59 UTC
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Knee surgery study aims to find safer cut for blood vessels
Knowledge-focused CompletedThis study looked at 40 adults with knee arthritis to compare two types of knee realignment surgery. The goal was to see which method keeps the important blood vessels behind the knee safer. Researchers used CT scans to measure the distance from the surgical cut to these vessels.…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 26, 2026 07:54 UTC
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Nurse training cuts infection risk in kidney stone surgery
Knowledge-focused CompletedThis study tested a teaching program to improve nurses' knowledge and practice of infection control for patients having a type of kidney stone surgery called percutaneous nephrolithotomy. Thirty nurses participated, and the goal was to see if training could reduce infections and …
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 26, 2026 07:53 UTC
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Fireworks eye injuries examined in upper egypt festival study
Knowledge-focused CompletedThis study looked at 59 people who came to the eye emergency room with injuries from fireworks during festivals in Upper Egypt in 2024. The goal was to understand who gets hurt, what types of injuries happen, and what the final eyesight results are. The study did not test any tre…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 26, 2026 07:50 UTC
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Liver cirrhosis patients tracked for 90-day survival in new study
Knowledge-focused CompletedThis study followed 100 adults hospitalized with liver cirrhosis to see how many survived 90 days after admission. Researchers also looked for factors that increased the risk of death. The goal was to better understand short-term outcomes, not to test a new treatment.
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 26, 2026 07:27 UTC
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New score may help doctors predict ICU outcomes for liver patients
Knowledge-focused CompletedThis study tested a special score called ICCO to see if it can predict which cirrhosis patients in the ICU are at higher risk of dying. Researchers calculated the score for 150 adults with cirrhosis admitted to the ICU and tracked their outcomes. The goal is to help doctors make …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Ultrasound test may predict newborn breathing issues in preeclampsia pregnancies
Knowledge-focused CompletedThis study looked at whether measuring blood flow in the lungs of unborn babies using Doppler ultrasound could help predict breathing problems after birth. Researchers studied 86 pregnant women with severe preeclampsia between 28 and 37 weeks of pregnancy. The goal was to see if …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Can a simple ultrasound predict Baby's health in preeclampsia?
Knowledge-focused CompletedThis study looked at 114 pregnant women to see if special ultrasound measurements of the baby's kidney and placenta could predict health problems in newborns. Researchers compared women with preeclampsia, a serious pregnancy condition, to healthy pregnant women. The goal was to f…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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New study aims to sharpen diagnosis of vocal cord abnormalities
Knowledge-focused CompletedThis study looked at 100 adults with irregular patches on their vocal folds. Researchers used a special camera (laryngostroboscopy) and standard tissue analysis to see if combining these methods improves diagnosis. They also checked if a specific gene (SOX2) could help identify t…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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Who seeks help for addiction? new study reveals key traits
Knowledge-focused CompletedThis study looked at 106 people being treated for substance use disorders at Assiut University Hospital. Researchers collected information on their personal background, drug use patterns, and personality traits. The goal was to better understand who is affected and how to improve…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 19, 2026 12:01 UTC
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Researchers map gum color patterns in healthy egyptians
Knowledge-focused CompletedThis study looked at gum color in 70 healthy Egyptian adults to see how common dark patches are and how they spread. Researchers used special scales to measure the color and pattern of pigmentation. The goal was simply to gather information, not to test a treatment.
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 19, 2026 11:48 UTC
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New blood test could help doctors manage postpartum bleeding
Knowledge-focused CompletedThis study looked at 90 women who had severe bleeding after childbirth (postpartum hemorrhage). Researchers used a device called Sonoclot to quickly measure how well their blood was clotting. The goal was to see if this test could help doctors spot clotting problems early and gui…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 18, 2026 12:12 UTC
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Tummy tucks after weight loss surgery: do they stop the regain?
Knowledge-focused CompletedThis study looked at 60 people who had sleeve gastrectomy (weight loss surgery) and then got body contouring surgery to remove extra skin and fat. Researchers wanted to see if the contouring surgery helped prevent weight regain and how it affected metabolism. They measured weight…
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 18, 2026 12:09 UTC
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Ultrasound score may predict best surgery for dangerous pregnancy condition
Knowledge-focused CompletedThis study looked at 154 pregnant women with placenta accreta (a condition where the placenta grows too deeply into the womb) to see if an ultrasound scoring system could help doctors choose the safest type of surgery. The goal was to predict whether a woman could have fertility-…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 18, 2026 12:07 UTC
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New clues to unexplained miscarriages: tiny molecules under the microscope
Knowledge-focused CompletedThis study looked at 86 women who had two or more unexplained miscarriages to see if certain molecules (microRNA 410 and BIRC7) might play a role. The goal was to find new clues about why some women experience recurrent pregnancy loss. No treatment was given; the study focused on…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 18, 2026 12:02 UTC