Assiut University
Clinical trials sponsored by Assiut University, explained in plain language.
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Laser vision showdown: which surgery works best for mixed astigmatism?
Disease control CompletedThis study compared two laser eye surgery techniques for people with mixed astigmatism, a specific type of vision problem. Researchers tested 39 participants to see whether femtosecond laser-assisted LASIK or single-step TransPRK surgery produced better vision results. The goal w…
Sponsor: Assiut University • Aim: Disease control
Last updated Apr 04, 2026 03:36 UTC
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Doctors test 'Pop Out' method to make repeat C-Sections safer
Disease control CompletedThis study tested a new surgical technique called 'external pop out' for delivering a baby's head during a repeat cesarean section (C-section). Researchers compared it to the standard method to see if it causes less damage to the mother's uterus, reduces bleeding, and shortens su…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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Egyptian study tests muscle relaxants vs. sedation alone for critical COVID patients
Disease control CompletedThis study compared two approaches for sedating COVID-19 patients with severe lung failure who needed breathing machines. Researchers tested whether adding muscle relaxants to standard sedation improved oxygen levels and survival compared to sedation alone. The trial involved 40 …
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Heart surgery breakthrough? new fluid formula tested to protect Patients' hearts
Disease control CompletedThis study compared two different protective fluid solutions used to stop and protect the heart during coronary artery bypass graft (CABG) surgery. It involved 124 adult patients undergoing planned heart surgery. Researchers tested whether a modified 'Del Nido' solution made with…
Phase: PHASE3 • Sponsor: Assiut University • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Study pits two kidney stone removal techniques Head-to-Head
Disease control CompletedThis study compared two modern, less invasive surgeries for removing kidney stones that are 2 centimeters or smaller. Researchers randomly assigned 118 patients to have either flexible ureteroscopy (f-URS) or mini-percutaneous nephrolithotomy (mini-PCNL). The main goal was to see…
Sponsor: Assiut University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Voice-Saving showdown: injection vs. therapy for nodules
Disease control CompletedThis study tested whether steroid injections directly into vocal nodules work better than a specific voice therapy method called the Accent Method. Researchers enrolled 50 adult women with vocal nodules to compare these two approaches. The goal was to see which treatment more eff…
Phase: PHASE4 • Sponsor: Assiut University • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Nerve block showdown: new injection tested to stop deadly brain spasms
Disease control CompletedThis study tested two different nerve-block injection procedures to treat dangerous blood vessel spasms (vasospasm) that can occur after a traumatic brain bleed. Sixty patients with this severe condition were randomly assigned to receive either a newer 'superior cervical' block o…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Nerve block injection tested to stop shingles pain from becoming permanent
Disease control CompletedThis study tested if a targeted nerve block injection could better control shingles pain and prevent it from turning into a long-term condition. It involved 100 adults with recent, painful shingles on their chest. Half received standard pain medication, while the other half also …
Phase: PHASE3 • Sponsor: Assiut University • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New hope for protecting Moms' kidneys in dangerous pregnancy complication
Disease control CompletedThis study compared two blood pressure medications to see which one better protects kidney function in women with severe pre-eclampsia in the intensive care unit. Researchers wanted to find out if a drug called phentolamine is safer for the kidneys than the commonly used drug gly…
Phase: PHASE4 • Sponsor: Assiut University • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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New scoring system aims to predict surgery type for dangerous pregnancy condition
Diagnosis CompletedThis study tested whether a specific ultrasound score, called the Placenta Accreta Index (PAI), could help doctors predict the best type of surgery for a serious pregnancy complication. Researchers followed 154 pregnant women with placenta previa and a prior C-section. The goal w…
Sponsor: Assiut University • Aim: Diagnosis
Last updated Apr 03, 2026 14:41 UTC
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New approach aims to spot vocal cord cancer earlier
Diagnosis CompletedThis study tested whether combining a special vocal cord camera (laryngostroboscopy) with standard tissue analysis could better diagnose unusual growths on vocal cords. Researchers studied 100 adult men with white patches or irregularities on their vocal cords to see if this comb…
Sponsor: Assiut University • Aim: Diagnosis
Last updated Mar 25, 2026 14:08 UTC
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Scientists hunt for better IBD blood test
Diagnosis CompletedThis study aimed to find better blood tests to diagnose inflammatory bowel diseases (IBD), like Crohn's disease and ulcerative colitis. Researchers measured four specific proteins in the blood of 70 newly diagnosed, untreated patients. The goal was to see if these proteins could …
Sponsor: Assiut University • Aim: Diagnosis
Last updated Mar 24, 2026 12:02 UTC
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New test aims to save mothers from dangerous Post-Birth bleeding
Diagnosis CompletedThis study tested a bedside device called Sonoclot to see if it could quickly assess blood clotting in women experiencing severe bleeding after delivery (postpartum hemorrhage). The goal was to see if this faster information could help doctors make better treatment decisions duri…
Sponsor: Assiut University • Aim: Diagnosis
Last updated Mar 23, 2026 15:18 UTC
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Mesh patch tested to prevent painful hernias after bowel surgery
Prevention CompletedThis study tested whether adding a supportive mesh patch during surgery to close a temporary intestinal opening (stoma) works better than standard closure. Researchers compared the two methods in 62 patients to see which one better prevents painful hernias, infections, and reduce…
Phase: NA • Sponsor: Assiut University • Aim: Prevention
Last updated Mar 20, 2026 14:54 UTC
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Virtual reality goggles tested to calm kids at the dentist
Symptom relief CompletedThis study tested whether using augmented reality (AR) goggles as a distraction could help reduce pain and anxiety in children aged 6-10 who were having a baby tooth pulled. Sixty children were randomly assigned to either use the AR goggles or receive the dentist's standard comfo…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Apr 04, 2026 03:50 UTC
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Doctors test new trick to soften tough cataracts during surgery
Symptom relief CompletedThis study tested a new step during cataract surgery for people with dense, brown cataracts. Surgeons paused the standard procedure to flush the cataract's core with fluid for 30 seconds, aiming to soften it. The goal was to see if this made the rest of the removal process easier…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Apr 04, 2026 03:50 UTC
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New drug combo aims to ease cancer pain with fewer opioids
Symptom relief CompletedThis study tested if adding the antidepressant duloxetine to the painkiller tramadol could better manage chronic cancer pain. It involved 400 adults with cancer pain who were not already on pain medication. The main goal was to see if the combination allowed patients to use less …
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Apr 03, 2026 14:43 UTC
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Two shots for knee pain: which works better after surgery?
Symptom relief CompletedThis study compared two different nerve-blocking injections to see which one better controls pain in the first 24 hours after knee arthroscopy (a minimally invasive 'scope' surgery). Fifty adults scheduled for this surgery received either a genicular nerve block (targeting nerves…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Apr 03, 2026 14:42 UTC
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New nerve block offers simpler, safer pain relief for broken ribs
Symptom relief CompletedThis study compared two methods for relieving severe pain in patients with multiple broken ribs. Researchers tested a newer, potentially simpler nerve block technique against a standard one to see which provided better and longer-lasting pain relief with fewer risks. The goal was…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Apr 03, 2026 14:41 UTC
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New nerve block technique tested for faster recovery after hip surgery
Symptom relief CompletedThis study compared two different nerve-block techniques for managing pain after hip fracture surgery. Researchers tested whether a newer combination nerve block (PENG + LFCN) works better than a standard nerve block (S-FICB) for pain relief and helping patients regain leg moveme…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Apr 03, 2026 14:41 UTC
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Eye socket breakthrough: doctors test two fixes for facial fractures
Symptom relief CompletedThis study compared two ways to surgically repair a broken eye socket (orbital floor fracture). 80 patients with this injury were randomly assigned to have their socket rebuilt using either a titanium mesh implant or a piece of their own hip bone. The goal was to see which method…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Apr 03, 2026 14:41 UTC
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Gallbladder surgery pain relief: study tests two Non-Opioid options
Symptom relief CompletedThis study tested two different non-opioid pain medications given during surgery to see which one better reduces pain after gallbladder removal. Researchers compared dexmedetomidine and lidocaine, both given as continuous infusions during the operation, in 64 patients. The goal w…
Phase: PHASE4 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Apr 02, 2026 14:58 UTC
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New study tests ways to make C-Section pain relief last longer
Symptom relief CompletedThis study aimed to find a better way to manage pain after a cesarean section. Researchers compared adding either magnesium sulphate or neostigmine to a standard numbing injection (TAP block) given after delivery. They measured how long pain relief lasted, how much extra pain med…
Phase: PHASE2, PHASE3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Doctors test two drugs to stop uncontrollable shaking after C-Sections
Symptom relief CompletedThis study compared two medications—dexamethasone and dexmedetomidine—to see which works better at preventing or reducing shivering after a cesarean section performed with spinal anesthesia. The trial involved 382 women who had elective C-sections. Researchers measured the severi…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Could a common mineral cut painkiller need after surgery?
Symptom relief CompletedThis study tested if adding magnesium sulfate to a standard pain-blocking injection could better control pain after breast cancer surgery. It involved 60 female patients who had a mastectomy. The main goal was to see if this approach reduced the total amount of strong opioid pain…
Phase: EARLY_PHASE1 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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New nerve block challenges gold standard for Post-Surgery pain relief
Symptom relief CompletedThis study compared two different methods for managing pain after major lower abdominal cancer surgery. Researchers tested a newer ultrasound-guided nerve block against the traditional epidural method, both using an enhancer medication called dexmedetomidine. The goal was to see …
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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New nerve blocks battle Post-Surgery pain
Symptom relief CompletedThis study compared two different nerve-block techniques to see which one better controls pain after inguinal hernia repair surgery. Researchers tested these methods on 43 male patients to help reduce the need for strong painkillers after the operation. The goal was to find a saf…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Could a simple Breathed-In solution ease your Post-Surgery throat pain?
Symptom relief CompletedThis study tested whether inhaling a magnesium mist before surgery could reduce sore throat and stress on the body caused by placing a breathing tube. It involved 100 generally healthy adults having planned gallbladder surgery. Half received the magnesium mist, while the other ha…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Pre-Surgery prep cuts pain and complications for women with cancer
Symptom relief CompletedThis study tested whether a special pre-surgery program could help women recover better from surgery for gynecologic cancers. The program included physical exercise, nutritional advice, and psychological counseling before the operation. Researchers compared 140 women who received…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Nutritional boost tested to ease agony of cancer treatment
Symptom relief CompletedThis study tested whether providing active nutritional support could help head and neck cancer patients receiving radiotherapy. It aimed to see if better nutrition could reduce the painful mouth sores (mucositis) that are a common and debilitating side effect of treatment. The go…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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New nerve block could ease Kids' pain after major hip operations
Symptom relief CompletedThis study tested a new method to manage pain in children aged 2-7 after hip reconstruction surgery. Researchers compared a newer ultrasound-guided nerve block (ESB) to a standard nerve block (caudal block) to see which provided better and longer-lasting pain relief after the ope…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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New nerve block combo could cut Post-Surgery pain meds
Symptom relief CompletedThis study tested whether adding ketamine or magnesium sulfate to a standard numbing injection (nerve block) could better control pain after breast cancer surgery. It involved 60 women undergoing surgery and measured how much morphine they needed afterward and how long their pain…
Phase: PHASE2 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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Common drug tested to ease pain after breast cancer surgery
Symptom relief CompletedThis study tested whether giving the drug mirtazapine around the time of surgery could help reduce pain after a mastectomy for breast cancer. It involved 62 women and measured their pain levels, need for morphine, and quality of recovery. The goal was to see if this approach coul…
Phase: EARLY_PHASE1 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 19, 2026 14:55 UTC
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Scientists test best way to block pain after keyhole chest surgery
Symptom relief CompletedThis study tested three different methods for managing pain after a specific type of minimally invasive chest surgery. Researchers compared how well each method worked to reduce pain and delay the need for additional pain medication. The goal was to find the most effective approa…
Phase: PHASE2 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 17, 2026 13:08 UTC
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New spinal injection combo aims to stop Post-Surgery sickness
Symptom relief CompletedThis study tested whether adding one or two specific drugs (dexamethasone or atropine) to the standard spinal anesthesia for a planned cesarean section could prevent the nausea and vomiting that morphine pain relief often causes. Researchers enrolled 150 women to compare the diff…
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 16, 2026 15:26 UTC
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Beyond pink: mapping Egypt's gum colors
Knowledge-focused CompletedThis study aimed to understand the natural patterns of gum pigmentation (color) in Egyptian adults. Researchers observed 70 healthy participants to document how common, how dark, and how widespread different gum colors are. The goal was to gather basic knowledge about this normal…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Scientists search for hidden causes of repeated pregnancy loss
Knowledge-focused CompletedThis study aimed to understand the biological reasons behind unexplained recurrent miscarriage. Researchers examined 86 women with a history of multiple miscarriages to explore how specific molecules in the body might affect pregnancy. The goal was to gather knowledge about poten…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Can better nurse training stop infections after kidney stone surgery?
Knowledge-focused CompletedThis study tested whether a special teaching program could improve nurses' knowledge and skills in preventing infections for patients undergoing a common kidney stone removal surgery (PCNL). It involved 30 nurses who care for these patients before, during, and after the procedure…
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Can a simple blood test predict cancer survival?
Knowledge-focused CompletedThis completed study aimed to see if certain blood measurements could help predict how newly diagnosed multiple myeloma patients might fare. Researchers followed 48 patients for one year after diagnosis, checking their blood thickness and protein ratios. The goal was to find conn…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Surgeons seek safer knee operation to protect blood vessels
Knowledge-focused CompletedThis study aimed to find out which of two common knee surgery techniques is safer for nearby blood vessels. Researchers compared the 'monoplanar' and 'biplanar' methods in 40 patients with knee osteoarthritis. They used CT scans to measure the distance between the surgical cut an…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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New calculator aims to predict survival for critically ill liver patients
Knowledge-focused CompletedThis study tested a new scoring system called the ICCO score to see how well it could predict survival for people with advanced liver disease (cirrhosis) who are admitted to the intensive care unit (ICU). Researchers enrolled 150 patients to calculate the ICCO score and compare i…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Why stomach bug treatments fail: scientists hunt for answers
Knowledge-focused CompletedThis study aimed to understand why antibiotic treatments sometimes don't work for H. pylori stomach infections. Researchers examined bacteria from 100 adult patients to see which antibiotics they resisted and what harmful genes they carried. They also looked at whether diet or ot…
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Researchers track 90-Day survival rates for hospitalized liver patients
Knowledge-focused CompletedThis study followed 100 adults hospitalized with liver cirrhosis to track what happened to them over 90 days after admission. Researchers wanted to understand how many patients passed away during this period and identify which factors put patients at higher risk. The goal was to …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Mar 06, 2026 15:37 UTC