New genetic clues could explain unexplained miscarriages
NCT ID NCT05658445
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aimed to find new reasons why some women have repeated miscarriages with no known cause. Researchers looked at specific genetic markers (microRNA 410 and BIRC7) in 86 women aged 20-30 who had two or three miscarriages. The goal was to better understand the disease, not to test a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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86 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Jun 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Female without cancer or chronic illness that exposed to 2 or 3 consecutive or discontinues abortion
- Ages
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20 to 30 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: maternal age is between 20 to 30 years and Gestational age before abortion less than 24 weeks. Female with unexplained two or three consecutive or discontinuous miscarriages with the same sexual partner Exclusion Criteria: 1. Female with one miscarriage 2. Female with explained causes of miscarriage 3. Female with cancer 4. Female with chronic illness. 5. Pregnant women above 30
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical Bochemistry Department
Asyut, Assuit, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.