Assiut University

This study looks at a surgery to repair partially torn anterior cruciate ligaments (ACL) in the knee. Researchers will track 30 people aged 15 to 50 to see how well the surgery improves knee function and stability. The goal is to help patients recover better and avoid a complete …

This study looks at whether adding the antibiotic azithromycin to usual treatment can shorten hospital stays for people with idiopathic pulmonary fibrosis (IPF) who are having a sudden flare-up. About 1000 adults with mild or early-moderate IPF will take part. Researchers will co…

This study tests whether giving tranexamic acid early after a traumatic brain injury can reduce harmful inflammation. Researchers will measure inflammation levels in 60 adults with mild to moderate head injuries. The goal is to see if this drug can improve recovery by controlling…

This study compares two surgical methods to help bring an undescended testicle down into the scrotum in boys. About 58 children with testicles that cannot be felt will be randomly assigned to have either the blood vessels cut or tied off during the first stage of a two-step surge…

This study tests a modified trabeculectomy surgery in 20 glaucoma patients whose previous combined cataract and glaucoma surgery did not control eye pressure well. The modified approach avoids cutting a layer called Tenon's capsule. The main goal is to see if it can safely lower …

This study tests whether a silver liquid (SDF) is better than standard fluoride varnish at reducing cavity-causing bacteria in children aged 3-8 with cavities on both sides of the mouth. Each child will get SDF on one side and fluoride varnish on the other, and bacteria levels wi…

This study tests a surgery for people with severe bowel leakage that hasn't improved with other treatments. The surgery uses a muscle from the buttock to create a new sphincter. The goal is to help patients gain better control and improve their quality of life.

This study is testing a new ultrasound measurement called the Lung Sliding Index (LSI) to see if it can help doctors tell apart different lung diseases like COPD, pneumonia, and pneumothorax. Researchers will measure LSI in 700 adults with various lung conditions and healthy volu…

This study tests whether a type of MRI that does not require a contrast dye (called biparametric MRI) can accurately diagnose bladder cancer and tell if it has spread into the muscle. Researchers will compare this simpler scan to the standard contrast MRI in 58 adults suspected o…

This study compares two ways to manage pain after major abdominal cancer surgery: a nerve block (TAP block) versus an epidural. The goal is to see which method is safer and reduces the need for morphine. The study will enroll 50 adults undergoing surgeries like gastrectomy or col…

This study looks at two low-dose medicines—dexmedetomidine and ketamine—to see which one works better for pain, diaphragm function, and inflammation in people with three or more broken ribs who are treated without surgery. About 60 adults aged 18-65 with severe pain will receive …

This study tests whether giving a numbing medicine (bupivacaine) as a mist before surgery can lower pain and the need for extra painkillers in children aged 1-7 having cleft palate repair. Half the children get the mist, half get a placebo, and neither the doctors nor families kn…

This study compares two breathing support methods—noninvasive ventilation (NIV) and high-velocity nasal cannula (HVNC)—in adults who develop respiratory failure within 48 hours after major surgery. The goal is to see which approach helps patients wean off breathing support sooner…

This study looks at whether adding blood flow restriction (BFR) training to standard physical therapy helps teens with spasmodic flatfoot more than therapy alone. About 40 adolescents who haven't improved with initial treatment will take part. Researchers will measure pain, foot …

This study looks at whether a rectus sheath block—a type of nerve block—can improve breathing and reduce pain in adults after major upper abdominal surgery. About 60 participants will receive the block and be monitored for diaphragm movement and pain levels. The goal is to see if…

This study tests if a nebulized (mist) form of tranexamic acid, a drug that helps blood clot, can reduce bleeding during sinus surgery. About 90 adults undergoing sinus surgery will receive either the drug or a placebo. The goal is to see if it makes the surgery easier for the su…

This study compares two minimally invasive procedures—semi-rigid and flexible ureteroscopy—to treat upper ureter stones smaller than 2 cm. Researchers will measure which method is more successful, safer, faster, and more cost-effective. The trial enrolls 100 adults with upper ure…

This study looks at whether a specific nerve block (erector spinae plane block) can reduce pain after laparoscopic abdominal surgery. Researchers will measure how long it takes for patients to need extra pain medicine and how much morphine they use. The study involves 50 adults u…

This study compares two breathing support methods—high flow nasal cannula and non-invasive ventilation—for people with bronchiectasis who are having a severe flare-up. The goal is to see which device is more effective and easier for patients to use. Twenty adults admitted to the …

This study compares two types of breathing support—high-velocity nasal insufflation (HVNI) and noninvasive ventilation (NIV)—in 100 adults with pneumonia who are having trouble breathing. The main goal is to see which method better prevents the need for a breathing tube or death …

This study compares two ways to sedate children before cleft palate repair: a mix of two drugs (dexmedetomidine and ketamine) given through a nebulizer versus dexmedetomidine alone. The goal is to see which approach helps children separate from parents more easily and reduces agi…

This study tests two types of breathing support for 70 adults with Guillain-Barré syndrome who have serious breathing trouble. One method uses a high-flow nasal cannula, and the other uses a mask that helps with both inhaling and exhaling. The goal is to see which approach helps …

This study tests two types of nerve blocks (TTPB and PIFB) to see which one better controls pain after open-heart surgery. About 90 adults aged 40-60 having coronary bypass will receive one of the blocks. The goal is to reduce pain and the need for extra painkillers, helping pati…

This study tests a new surgical technique that uses two types of scopes (hysteroscope and laparoscope) to repair a uterine niche—a pocket in the C-section scar that can cause spotting after periods. The goal is to see if this combined approach better relieves symptoms and increas…

This study looks at two types of nerve blocks—pectoral nerve block and paravertebral block—to see which one better prevents chronic pain after mastectomy. About 90 women having breast removal surgery will be randomly assigned to receive one of the blocks. The goal is to reduce lo…

This study looks at whether starting to walk right after pelvic fracture surgery is better than waiting. It involves 50 adults aged 18 to 55 who had specific types of pelvic fractures fixed with surgery. The goal is to see which approach improves function, pain, walking, and qual…

This study is testing whether giving children a medicine called tranexamic acid during hip reconstruction surgery can reduce blood loss and the need for blood transfusions. The trial will include 400 children who are scheduled for this type of surgery. Researchers will measure bl…

This study tests whether behavioral therapy can ease chronic cough in adults whose cough persists despite standard treatments. Participants must have signs of laryngeal hyperresponsiveness, like coughing when talking or in cold air. The study will measure changes in cough severit…

This study is testing a new tool called CLEAR to see if it can better predict when people with severe COPD can safely stop using a breathing machine. Researchers will study 400 adults in the ICU who are ready to try breathing on their own. The goal is to improve decision-making a…

This study is observing 750 adults with non-cystic fibrosis bronchiectasis to develop a model that can identify different types of the disease based on patient data. The goal is to help doctors predict how the disease will progress and tailor care more effectively. No new treatme…

This study looks at how heart problems impact the severity and quality of life in people experiencing a sudden worsening of bronchiectasis (a lung condition). Researchers will compare 30 participants with both bronchiectasis and heart conditions to a control group. The goal is to…

This study aims to see if special MRI scans can predict how well chemotherapy works in people with muscle-invasive bladder cancer. Researchers will scan 39 patients before, during, and after treatment to look for early signs of success or failure. The goal is to help doctors deci…

This study looks at whether chemotherapy given before bladder cancer surgery makes MRI scans less accurate at showing the tumor stage. About 76 people with muscle-invasive bladder cancer will take part. Some will get chemotherapy before surgery, and others will go straight to sur…

This study looks at why some thyroid nodule biopsy samples are not good enough for diagnosis. Researchers will collect samples from 160 people and check factors like needle size and technique. The goal is to reduce the need for repeat biopsies, which can be uncomfortable and cost…

This study looks at whether ultrasound can detect nerve changes in people with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Researchers will compare ultrasound images with standard nerve tests to see if ultrasound helps diagn…