New combo may cut opioid use for cancer pain
NCT ID NCT05311774
First seen Jan 11, 2026 · Last updated May 21, 2026 · Updated 21 times
Summary
This study tested whether adding duloxetine (a nerve pain drug) to tramadol (a painkiller) helps people with chronic cancer pain use less tramadol. 400 adults with cancer pain who had not taken painkillers before took part. Half received duloxetine plus tramadol, the other half a placebo plus tramadol. The goal was to see if the combination lowers the amount of tramadol needed for pain relief.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Assiut University
Asyut, 71111, Egypt
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