Could a simple mineral boost pain relief after breast cancer surgery?
NCT ID NCT05976464
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding magnesium sulfate to a standard nerve block (erector spinae plane block) reduces pain and the need for morphine after a mastectomy. Sixty women scheduled for breast cancer surgery took part. The main goal was to see how much morphine they needed in the first 24 hours after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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60 people
The number who actually took part.
- Started
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Jul 2023
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 1\. ASA I-II. 2. Female patients aged 18-65 years. 3. Scheduled for a modified radical mastectomy with axillary dissection for breast cancer. Exclusion Criteria: 1. ASA \< II. 2. more than 65 years old 3. Patients with known allergies to the study drugs 4. Skin infection at the site of needle puncture. 5. Coagulopathy 5\. Drug or as that would interfere with perception and assessment of pain. 6. Uncooperative patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Assuit University -South Egypt Cancer Institute
Asyut, Assuit, 71511, Egypt
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Other studies related to the condition(s) this trial covers.
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