Could belly fat worsen heartburn? new study investigates
NCT ID NCT07302022
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will examine how metabolic syndrome—a cluster of conditions like high blood pressure, high blood sugar, and excess belly fat—relates to gastroesophageal reflux disease (GERD). Researchers will enroll 50 adults with metabolic syndrome and use an endoscopy to check for signs of GERD. The goal is to see if certain metabolic factors make GERD more likely or more severe.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could clarify how metabolic syndrome contributes to GERD, potentially guiding future prevention or treatment strategies.
- What could go wrong
- This is a small, observational study that does not test any treatment. It can only show associations, not cause and effect, and results may not apply to broader populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Community sample
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- 2.3.1-Type of the study: This study will be designed as an observational, cross-sectional, analytical study. 2.3.2-StudySetting: This study will be performed at internal medicine, Assuit University Hospitals 2.3.3-Studysubjects: 1. Inclusion Criteria: * Adult patients aged 18 years and above. * Patients diagnosed with metabolic syndrome based on standard criteria (e.g., NCEP ATP III). * Patients who will undergo upper gastrointestinal (GI) evaluation for GERD symptoms. 2. Exclusion Criteria: 1. Patients with a history of upper GI surgery. 2. Pregnant or lactating women. 3. Patients with known malignancy or severe comorbid illness. 4. Patients currently taking proton pump inhibitors (PPIs) or other acid-suppressive therapy. 5. Unwilling or unable to provide informed consent. Exclusion Criteria: \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Assiut university hospitals
Asyut, Asyut Governorate, Egypt
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