Can a simple blood test predict rebleeding in gut vessel disease?
NCT ID NCT07183995
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will check 55 adults with gastrointestinal angiodysplasia—abnormal blood vessels in the gut that can cause bleeding—for related blood disorders, especially problems with von Willebrand factor, a protein that helps blood clot. Researchers want to see if low levels of this protein can predict who will bleed again or die in the hospital. Participants will undergo standard tests like endoscopy, colonoscopy, and blood work. The study does not test any new treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better predict which patients with GI angiodysplasia are at risk of rebleeding, potentially guiding more personalized monitoring or treatment.
- What could go wrong
- This is an observational study with only 55 participants, so results may not apply to everyone. It aims to find associations, not test a treatment, so it won't directly change care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 55 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All patients eligible to participate will undergo the following: 1. upper endoscopy 2. Colonoscopy 3. Complete blood count, CRP 4. D-Dimer, liver function tests, blood Urea and serum Creatinine 5. ECG 6. Coagulation profile (aPTT , von Willebrand factor activity \&antigen)
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Adults (above 18 years) and elderly Both genders Admitted to GIT Unit with manifestations of GIT bleeding diagnosed by upper endoscopy and Colonoscopy as angiodyplasia. \- Exclusion Criteria: other causes of GIT bleeding \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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