Could a simple mineral prevent brain damage after head trauma?
NCT ID NCT07252505
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving magnesium sulfate early through an IV can reduce dangerous narrowing of brain arteries after a traumatic brain bleed. About 50 adults with head injuries will receive the treatment within 24 hours. The goal is to see if it lowers the risk of delayed brain damage and improves recovery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2025
An estimate. Start dates often move.
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged between eighteen to sixty five years Diagnosed with tSAH on Head Computed Tomography(CT)within 24 hours of trauma. * Both Genders are included Indication for endovascular or microsurgical treatment plan Exclusion Criteria: * Aneurysmal or spontaneous SAH Sever hepatic dysfunction. * Known hypersensitivity to magnesium sulfate * Renal disease with glomerular filtration rate\<15 ml/min. * pregnancy
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Conditions
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