New study: could a simple ketamine wash ease pain after gallbladder surgery?
NCT ID NCT07370181
First seen Jun 27, 2026 · Last updated Sep 16, 2026 · Updated 4 times
Summary
This study tests whether adding ketamine to a standard painkiller (bupivacaine) and rinsing the surgical area during gallbladder removal can better control pain after surgery. Sixty adults having laparoscopic gallbladder removal will be randomly assigned to receive either the standard painkiller alone or with ketamine. The goal is to see if the ketamine group needs less rescue pain medication and reports lower pain scores in the first 24 hours after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with age ≥18 years of ASA I-II who will be scheduled for elective laparoscopic cholecystectomy under general anesthesia. Exclusion Criteria: * History of congenital heart disease * Hypertension * Developmental delay, or * Allergy to study drugs
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Assiut University
Asyut, Assuit, Assuit universi, Egypt
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Other studies related to the condition(s) this trial covers.
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