New spine surgery for kids shows early promise
NCT ID NCT07429656
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study will test a new surgical technique called Active Apex Correction (APC) in 15 children under 10 with early onset scoliosis. The procedure aims to straighten the spine by placing screws only on the outer side of the curve, avoiding cuts to the spine bones. Researchers will measure how much the spine lengthens and the curve improves after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Active Apex Correction (APC) surgical procedure
- What this could lead to
- If successful, this technique could offer a less invasive surgical option for young children with scoliosis, potentially reducing complications and improving spine growth.
- What could go wrong
- This is a very small pilot study (15 participants) with no control group. The procedure is new and may not be safer or more effective than existing surgeries. Risks include surgical complications and limited generalizability.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 15 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Up to 10 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All patients with progressive early onset scoliosis (congenital, idiopathic, neuromuscular or syndromic). * Major curve Cobb angle ≥ 40° * Child below 10 years of age or less than Risser grade 2 * No prior scoliosis surgery Exclusion Criteria: * Age above 10 years or more than Risser grade 2. * Operated EOS cases indicated for revision. * Active infection or systemic illness precluding surgery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Assiut University Hospital
Asyut, Asyut Governorate, 71511, Egypt