Which anesthesia drug protects the heart better in cancer surgery?
NCT ID NCT07214714
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two medications, dexmedetomidine and fentanyl, given during general anesthesia for major abdominal cancer surgery. The goal is to see which drug better maintains heart function and stability. About 70 adults undergoing elective surgery will participate, and their heart output will be monitored non-invasively.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ASA physical status I- III, NYHA class I- II * Patients subjected to elective major abdominal cancer surgeries. * The enrolled age will be ≥ 18 years. Exclusion Criteria: * Unfit for surgery * Patient refusal * Body mass index\>40 kg/m2 * ASA physical status IV-V, NYHA class III-IV. * Chronic opioid consumption * Contraindications to neuraxial block (coagulopathy, infection, or hematological disorders). * Pregnant women * Hypersensitivity to any of the used drugs
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.