Could low vitamin d worsen IBD? new study investigates
NCT ID NCT07259603
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will measure vitamin D levels in 100 adults with inflammatory bowel disease (Crohn's or ulcerative colitis) to see if low vitamin D is linked to more active disease. Participants will have blood tests for vitamin D and inflammation markers. The goal is to better understand the relationship, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If it works, this could clarify whether low vitamin D is linked to worse IBD symptoms, possibly pointing toward better monitoring or supplementation strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not change clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
* Adults aged ≥18 years * Diagnosed with crohn's and ulcerative colitis * Regular follow-up as an outpatient in the IBD clinic at Al-RAGHI hospital Assuit university * Recent vitamin D and disease activity assessment (within 1 month) * Sample Size Calculation: Assuming an expected prevalence of vitamin D deficiency in IBD patients around 50%, a sample size of n = 100-150 will give adequate power (80%) to detect significant correlations (p \< 0.05) between vitamin D levels and disease activity indices.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged ≥18 years * Diagnosed with crohn's and ulcerative colitis * Regular follow-up in IBD clinic * Recent vitamin D and disease activity assessment (within 1 month) Exclusion Criteria: * Current vitamin D supplementation(\>1000IU/day) * History of malabsorption syndromes (e.g.,celiac disease) * Chronic kidney or liver disease * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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