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New study aims to uncover hidden bleeding disorder in egyptian kids

NCT ID NCT07410130

Knowledge-focused Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will look at how common von Willebrand disease is among children in Upper Egypt, what symptoms they have, and how they are treated. Researchers will review medical records and lab tests from 25 children aged 0-18 with suspected or confirmed VWD. The goal is to improve diagnosis and care for this inherited bleeding disorder in the region.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors in Upper Egypt better recognize and treat von Willebrand disease in children, leading to fewer complications and hospital visits.
What could go wrong
This is a small, observational study that only looks at existing medical records and tests. It won't test new treatments, so it may not directly change care right away.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 25 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study includes pediatric patients aged 0 to 18 years with suspected or confirmed von Willebrand disease (VWD) who are residents of Assiut Governorate or are receiving medical care at Assiut University Children's Hospital. The study population represents children evaluated for bleeding symptoms or referred for assessment of possible inherited bleeding disorders within a tertiary pediatric healthcare setting. Eligible participants are identified based on clinical presentation suggestive of VWD, such as recurrent epistaxis, easy bruising, mucocutaneous bleeding, prolonged bleeding following trauma or surgical procedures, and heavy menstrual bleeding in adolescent females. Both newly evaluated patients and previously diagnosed cases with accessible medical records are included to allow comprehensive assessment of disease frequency, clinical spectrum, and management outcomes. All participants undergo standardized clinical evaluation, including detailed medical history, family history

Ages

0 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 0-18 years. 2. Residents of Assiut Governorate or receiving care at Assiut University Children's Hospital. 3. Suspected or confirmed von Willebrand disease (VWD) based on clinical bleeding symptoms or referral for evaluation. 4. Patients diagnosed with VWD using standard laboratory tests, including: 5. VWF antigen (VWF:Ag). 6. VWF ristocetin cofactor activity (VWF:RCo). 7. Factor VIII activity. Exclusion Criteria: 1. Other inherited bleeding disorders, such as: 2. Hemophilia A or B. 3. Rare coagulation factor deficiencies (e.g., factors I, V, VII, X, XI deficiency). 4. Platelet function disorders. 5. Acquired bleeding disorders, including: * Liver disease. * Renal insufficiency. * Vitamin K deficiency. * Disseminated intravascular coagulation (DIC). * Use of medications that may interfere with coagulation testing (e.g., anticoagulants, antiplatelet drugs). * Incomplete clinical or laboratory data (for retrospective cases). * Refusal of consent for participation (for prospective cases).

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Conditions

The condition(s) this trial relates to.

hemophilia A inherited blood coagulation disorder Menorrhagia von Willebrand disease (hereditary or acquired)

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inherited bleeding disorders in children Pediatric hemostatic disorders Von Willebrand disease (VWD)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Assiut university

    Asyut, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.