Stroke disorder

This study compares a virtual reality (VR) rehabilitation program that combines movement and cognitive training in realistic everyday environments with conventional occupational therapy for people who have had a stroke. The goal is to see if the VR program leads to greater improv…

This study tests a device called the Penumbra System with Thunderbolt Aspiration Tubing to remove blood clots in people having a severe stroke caused by a blockage in a large brain artery. The goal is to see if the device can safely and effectively restore blood flow within 8 hou…

This study explores whether combining a high-protein Mediterranean diet with resistance exercise can help people with heart disease build muscle and lower their risk of future heart problems. The trial enrolls adults who have completed cardiac rehab and may have low muscle mass w…

This pilot study tests a new non-invasive brain stimulation device called kTMP (kilohertz transcranial magnetic perturbation) to see if it can improve arm and hand movement in people who had a stroke more than six months ago. The study enrolls 7 adults aged 18-80 with stable uppe…

This study tests whether a three-month smartphone-supported walking program can improve daily step counts, psychological well-being, and body composition in adults with cardiovascular disease or type 2 diabetes. Participants use the Walk15 app to set personalized step goals and t…

This study tested a coaching program called MACRO-I for adults aged 70 and older who had a heart event. The program used coaches to guide patients through starting cardiac rehab, either at a center, at home, or a mix of both. 416 participants were split into the coaching group or…

This study tests whether a smart bracelet system can help hospitals treat stroke patients faster. The bracelets track where patients are in the emergency room and send alerts if treatment is delayed. The goal is to shorten the time between arrival and life-saving clot-busting the…

This phase 2 trial tested a new gel called OTR4132 in 60 people who had a stroke and received a clot-removal procedure. The gel is designed to help repair damaged brain tissue. Researchers measured neurological function at 24 hours and disability at 3 months to see if the gel imp…

This study tests whether combining two types of electrical stimulation can improve hand and arm movement in people who recently had a stroke. One stimulation is applied to the brain (tDCS) and the other to a nerve in the wrist. Participants receive five daily sessions, and their …

This study looked at how well a mechanical device works to remove blood clots from the brain during a stroke. Researchers followed 230 adults who had a stroke within the previous 8 hours and received the procedure. The goal was to see if the treatment helps patients recover and r…

This study tested whether a combination of small amounts of tube feeding plus extra nutrition through an IV could reduce pneumonia in people with severe stroke. The trial enrolled 546 adults who had trouble swallowing. Researchers compared this approach to standard full tube feed…

This trial investigates whether adding strength training for the tibialis anterior muscle (which lifts the foot) to proprioceptive (balance) exercises improves recovery in people who had a stroke at least six months ago. Participants will be assigned to six weeks of either balanc…

This study compares two different doses of Wii Fit-based virtual reality balance training added to standard physical therapy for people who had a stroke at least six months ago. Participants are randomly assigned to receive either conventional rehab alone, or conventional rehab p…

This phase 2 trial tests whether baricitinib, an anti-inflammatory drug, can improve neurological outcomes in people who have had a spontaneous intracerebral hemorrhage (a type of stroke caused by bleeding in the brain). About 110 adults in China will receive either baricitinib p…

This study tested whether Mongolian medicine ZhenBao Pills help people recover arm function after an ischemic stroke. 216 adults who had a stroke within the past 30 days took either the pills or a placebo twice daily for 90 days. The main goal was to see if arm movement improved …

This study tested whether a special balloon procedure, called direct ischemic post-conditioning, can reduce brain injury in people who just had a stroke from a large blocked artery. Sixty patients were randomly assigned to get either standard clot removal alone or clot removal pl…

This study tests whether using a blood test to guide antiplatelet medication can reduce the risk of a second stroke. People who have had a non-cardioembolic ischemic stroke and are already taking aspirin will be assigned to either continue standard aspirin or switch to a differen…

This study tested a soft robotic sock called VACOM in 19 stroke patients who had trouble moving their ankle. The sock gently moves the ankle to prevent stiffness and improve blood flow, aiming to reduce the risk of blood clots and contractures. The trial is complete, but results …

This study tested whether giving a powerful cholesterol-lowering drug (evolocumab) along with standard statins within 48 hours of a stroke could prevent early neurological decline. It included 429 adults with moderate to severe narrowing of brain arteries. The goal was to see if …

This study tested a drug called Edaravone (MCI-186) in 36 people who had an acute ischemic stroke. The goal was to check the drug's safety and how the body processes it. Participants received either Edaravone or a placebo through an IV over 72 hours. The trial was completed, but …

This study looked at whether a therapeutic education program, added to standard medical care, helps people who have had a heart attack or stroke better control their risk factors over one year. About 202 adults aged 18-75 took part. The goal was to see if the program improves phy…

This pilot study tested whether adding cognitive rehabilitation to a standard occupational therapy telerehabilitation program helps stroke survivors improve thinking, arm function, and mood. Twenty adults who had a stroke at least 30 days prior participated in an 8-week home-base…

This study tested a new intensive therapy called I-ACQUIRE for infants aged 8 to 36 months who had a stroke around birth and have weakness on one side. The therapy involves guided play and movement exercises for either 3 or 6 hours a day, 5 days a week for 4 weeks. Researchers co…

This study tested whether combining brain stimulation, nerve stimulation, and hand exercises can help people with chronic stroke regain hand movement. Fifty-one participants who had a stroke at least six months prior received the combined therapy. The goal was to see if it streng…

This pilot study tested a device called Fesia Grasp that uses electrical stimulation to help people recovering from a stroke regain hand function. Sixteen participants with arm weakness after a subacute stroke received either Fesia Grasp therapy or standard physical therapy. The …

This study tested whether the drug rivaroxaban works as well as warfarin to prevent further brain damage in people who have had a stroke due to antiphospholipid syndrome (APS), a condition that causes abnormal blood clotting. About 40 participants took either rivaroxaban or warfa…

This completed study tested a new device called the Supernova stent retriever in 55 people with severe stroke caused by a large blood clot in the brain. The device is threaded through blood vessels to grab and remove the clot, restoring blood flow. Researchers measured how often …

This study tested whether a newer blood thinner, rivaroxaban (Xarelto), is as safe and effective as the older drug warfarin for preventing strokes in people who develop atrial fibrillation after heart surgery. About 100 adults who had open-heart surgery and then experienced a new…

This study tested whether a physical activity program delivered by mail and website could improve the health of nearly 50,000 older women already in the Women's Health Initiative. The program included aerobic, balance, strength, and flexibility exercises, and encouraged reducing …

This study tested a new way of caring for stroke patients that brings together doctors, nurses, and family members using technology and teamwork. About 1,200 adults who had a stroke took part. The goal was to see if this coordinated care helps people recover better and have a hig…

This study tested whether using social networks (like family and friends) can help people at high risk for stroke stick to their medications and control risk factors after leaving the hospital. Researchers enrolled 720 patients and compared standard care with a social network-bas…

This study looked at whether a procedure to remove a blood clot from the brain (endovascular therapy) works better than medication alone for people with mild stroke symptoms and a visible clot. About 4,800 adults with mild stroke were included. The goal was to see which approach …

This study tested whether giving a powerful cholesterol-lowering drug (evolocumab) within 6 hours after a stroke procedure (thrombectomy) could prevent early neurological worsening. 60 adults with large-vessel stroke were randomly assigned to receive either the drug plus standard…

This study tested a 6-month program called TEAM designed to help African-American men who have had a stroke or mini-stroke manage their health better. The program included group sessions with a nurse and peer educators, focusing on lifestyle changes to lower blood pressure and ch…

This completed trial tested whether combining a gentle brain stimulation technique called tDCS with intensive rehabilitation can improve hand function in children with hemiplegic cerebral palsy caused by perinatal stroke. 89 children participated, and the study measured changes i…

This study tested whether adding dornase alfa (a drug used for cystic fibrosis) to standard clot-busting treatment could improve blood flow before a clot removal procedure in people having a major stroke. 330 adults with acute ischemic stroke and a large vessel blockage were enro…

This study tested whether colchicine, a drug used for gout, can reduce inflammation in the arteries of people with diabetes who recently had a heart attack or stroke. Researchers used a special PET scan to measure inflammation in the blood vessels. 115 participants were randomly …

This study tested a rehabilitation technique called blood flow restriction training (BFRT) in 70 stroke survivors with arm weakness on one side. Participants did low-intensity exercises while wearing a cuff that partially restricted blood flow to the affected arm. The goal was to…

This completed study tested a device called MR-001 that uses rhythmic auditory stimulation (like music or beats) to help people who have had a stroke walk better. 234 chronic stroke patients with walking problems used the device at home for 12 weeks. The goal was to see if it imp…

This study tested whether giving the cholesterol-lowering drug evolocumab within 24 hours after clot-busting treatment (thrombolysis) can prevent early neurological decline in people with acute ischemic stroke. 132 participants were randomly assigned to receive evolocumab plus st…

This study tested whether a 40-hour, 8-week cognitive telerehabilitation program could reduce the risk of memory and thinking problems after a stroke. 86 adults who recently had a stroke were randomly assigned to either the home-based brain training or standard care. The program …

This study tested a once-daily pill called orforglipron against insulin glargine in nearly 2,750 adults with type 2 diabetes, obesity or overweight, and increased cardiovascular risk. The main goal was to see if orforglipron could reduce major heart events like heart attacks or s…

This study tested whether a powerful blood thinner called tirofiban can improve recovery in people with a specific type of stroke called branch atheromatous disease (BAD). BAD strokes often get worse quickly and have few good treatments. The trial enrolled 516 adults within 48 ho…

This pilot study tested whether low-frequency magnetic stimulation (rTMS) applied to the brain within 48 hours of an acute ischemic stroke could reduce the growth of damaged tissue and lower disability. Sixty adults aged 18–80 with moderate to severe strokes were enrolled. The tr…

This study tested the WATCHMAN device, a small implant that closes off a part of the heart where clots often form, in 481 people with atrial fibrillation who cannot take blood thinners. The goal was to see if the device is safe and effective at reducing stroke risk. Participants …

This study tested whether low-frequency magnetic brain stimulation (rTMS) can improve recovery in 60 people who had a severe stroke and received emergency treatment to reopen blocked arteries. Participants received either real or sham stimulation for 3 days after their procedure.…

This study tested two blood thinners—tirofiban and aspirin—in 240 stroke patients who also had a severe blockage in the neck artery. The goal was to see which drug better prevents the artery from reclosing after emergency surgery, while also checking for bleeding risks. Results w…

This study tested a new medical wire, called the Tarvos Microguidewire, used during surgery on blood vessels in the brain. The wire helps doctors guide other tools to the right spot. Researchers looked back at records of 121 patients who had this wire used in their surgery for co…

This study tested whether giving a clot-busting drug directly into the brain's fluid spaces could save lives after a severe brain bleed caused by a burst aneurysm. Nineteen patients with heavy bleeding inside the brain's chambers received the treatment. The main goal was to see i…

This study tested whether giving heparin (a blood thinner) during brain angiography can prevent the radial artery in the wrist from becoming blocked afterward. The trial involved 440 acute stroke patients and compared heparin to a placebo. The goal was to see if heparin reduces a…

This study tested whether adding sodium sivelestat, a drug that reduces inflammation, to standard mechanical thrombectomy could improve outcomes in 20 stroke patients with large vessel occlusion. The drug aims to prevent 'futile recanalization,' where blood flow is restored but p…

This completed study looked at whether a fixed dose of a drug called 4F-PCC is safe and effective for reversing the effects of common blood thinners (rivaroxaban or apixaban) in patients with brain bleeding. Researchers compared this fixed-dose approach to the standard weight-bas…

This study tested whether using a 3D-printed model of a heart chamber helps doctors better plan a procedure to close off a small pouch in the heart. This pouch, called the left atrial appendage, is a common source of blood clots that can cause stroke in people with atrial fibrill…

This study tested whether a year of twice-weekly resistance training could protect brain health and thinking skills in 91 older adults with vascular cognitive impairment, a condition linked to small strokes. Participants were randomly assigned to either resistance training or a s…

This early study tested a new device that cools the brain in 8 people who had a stroke caused by a large blood clot. After doctors removed the clot, the device cooled the brain for 30 minutes to try to protect it from further damage. The main goal was to see if the cooling was sa…

This study tested whether using a special tongue brush (Orabrush) can lower the chance of aspiration pneumonia and improve swallowing in people who had a stroke. Researchers enrolled 252 stroke patients and compared those who used the brush to those who did not. The goal was to s…

This pilot study tested whether community pharmacists can manage blood thinner therapy for older adults (60+) with atrial fibrillation who are at high risk for stroke but not on optimal treatment. Fourteen participants received pharmacist-led care for 3 months, then were followed…

This study tested whether using a balloon-guided catheter helps doctors remove blood clots more effectively in people having a stroke. 110 adults with acute ischemic stroke were randomly assigned to receive clot removal with either a balloon-guided or standard catheter. The main …

This study tested whether giving the blood-thinning drug tirofiban after mechanical clot removal improves outcomes for people with severe stroke. Over 1,300 participants were randomly assigned to receive tirofiban or a placebo. The goal was to see if more patients could live inde…

This study tested a new device called the Millipede System in 246 stroke patients with large blood clots in the brain. The device is designed to remove clots and restore blood flow. Researchers measured how often blood flow was successfully restored and tracked any side effects. …

This study tested whether a medicine called milrinone, given through a vein, can help people recover better from a serious type of stroke called subarachnoid hemorrhage. After this stroke, many patients develop dangerous spasms in brain arteries that can cause further brain damag…

This study tested two types of nerve blocks (superior cervical sympathetic block and stellate ganglion block) to treat blood vessel spasms in the brain after a traumatic head bleed. The goal was to improve blood flow and prevent further brain damage. The study included 60 adults …

This completed trial tested a new stent (SINOMED SR) for removing blood clots in 218 people with acute ischemic stroke. The stent was used within 24 hours of symptom onset. The main goal was to see if the stent could successfully reopen blocked brain arteries. Researchers also tr…

This completed study tested a health system intervention called ENHANCE in 1,837 adults aged 40+ with at least two chronic conditions (HIV, high blood pressure, diabetes, asthma, or depression). The intervention included a clinical decision support tool for clinicians, health edu…

This study tested a device called SynPhNe that combines physical therapy with brain feedback to help stroke patients improve hand movement. Fifty-one recent stroke survivors used the device alongside standard therapy. The goal was to see if it could boost recovery and be used wit…

This study tested an experimental drug called SCP776 in 120 adults having emergency surgery to remove a blood clot after a severe stroke. The goal was to see if the drug is safe and helps protect the brain from further damage. Participants received either the drug or a placebo, a…

This study tested whether giving N-Acetylcysteine (NAC) intravenously soon after an acute ischemic stroke could improve outcomes. Only 4 adults with moderate to severe stroke were enrolled. Researchers measured stroke severity and disability at 30 and 90 days. The trial is comple…

This study tested whether adding neuromuscular electrical stimulation (NMES) to standard swallowing therapy helps stroke patients with difficulty swallowing. Sixty adults who recently had a stroke and needed tube feeding took part. They received either NMES plus therapy or a sham…

This study tested a 12-week walking program for 140 chronic stroke survivors. The program combined robotic-assisted walking with regular walking exercises. The goal was to improve walking ability, help with weight management, and lower blood pressure. Researchers wanted to find t…

This study tested whether special ankle exercises could improve balance and walking in people who had a stroke at least a year ago. 140 participants were split into two groups: one did the ankle training plus standard gait training, the other did standard gait training alone. Aft…

This study tested whether giving a clot-busting drug (tenecteplase) before mechanical clot removal helps people with a severe type of stroke caused by a blockage in the basilar artery. The trial included 330 adults who were treated between 4.5 and 24 hours after stroke symptoms b…

This study tested whether special pelvic floor exercises can help stroke survivors who have weak pelvic muscles and sexual problems. 140 people who had a stroke at least a year ago took part. The goal was to see if these exercises improve muscle strength and sexual function over …

This study tested whether intensive dental cleaning and oral hygiene advice can improve gum health and also affect markers of heart disease and type 2 diabetes. About 200 adults with gum disease and either heart disease or diabetes (or prediabetes) took part. Researchers measured…

This early-stage study tested whether a single intravenous infusion of stem cells from human umbilical cord tissue is safe for people who had an ischemic stroke 3 to 6 months earlier. 18 participants were monitored for side effects and any improvement in daily function. The goal …

This phase 3 trial tested whether giving a clot-dissolving drug called tenecteplase directly into the brain artery can improve blood flow in stroke patients who still have blockages after standard mechanical clot removal. 156 adults with acute ischemic stroke were randomly assign…

This study tested a brain-computer interface (BCI) combined with functional electrical stimulation (FES) to help stroke survivors with foot weakness walk better. 62 adults who had a stroke at least 6 months prior and had trouble walking participated. The therapy used brain signal…

This small completed study looked at a blood filtering procedure called double-filtration plasmapheresis (DFPP) in 5 kidney dialysis patients with very high levels of lipoprotein(a), a fatty substance linked to heart disease and blood clots. The goal was to see if DFPP could lowe…

This study tested a device called the Lariat to close off a small pouch in the heart (the left atrial appendage) in people with atrial fibrillation who cannot take blood thinners. The goal was to reduce the risk of stroke. Nine participants were enrolled, and the study measured h…

This study tested a supplement called HOV-12020 (made from palm tocotrienols) in 50 adults aged 45-75 with CADASIL, a rare genetic disease that damages small blood vessels in the brain, leading to strokes and memory loss. The goal was to see if the supplement could reduce worseni…

This study tested a nurse-guided phone program for 500 recent stroke patients in Ghana to help them manage their blood pressure at home. The program included home blood pressure monitoring, medication reminders, and education on heart health. The goal was to see if this approach …

This study tested a device called Artemis that removes blood clots from the brain through a small hole, instead of open surgery. It included 236 adults aged 18 to 80 with a specific type of brain hemorrhage. The goal was to see if this less invasive approach leads to better recov…

This study tested a culturally-tailored program called HARMONY for African American women at risk for heart disease, stroke, and diabetes. Over 8 sessions plus monthly boosters, participants learned stress management, exercise, and healthy eating. The goal was to see if the progr…

This study tested a new tool called BESTA, designed to quickly diagnose aphasia (language problems) in people who just had a stroke. Researchers compared BESTA to an existing test in 395 participants, including stroke patients and healthy volunteers. The goal was to see if BESTA …

This study looked at whether measuring two proteins in the blood (GST-π and PRDX1) can accurately determine if a stroke occurred within the last 4.5 hours. That time window is critical because it determines if patients can receive clot-busting medication. Researchers enrolled 935…

This pilot study tested whether a quick, 20-second ultrasound of the brain's blood vessels could help paramedics identify patients with a severe stroke caused by a large blocked artery. The study included 60 participants: healthy volunteers and suspected stroke patients. Research…

This study tested whether a non-invasive device placed on the forehead (NIRS) can detect blood vessel spasms in the brain after a severe aneurysm rupture. Fifty patients were monitored continuously from day 4 to day 12 after their bleed. The goal was to see if this oxygen-measuri…

This study tested whether a special CT scan done in the procedure room can accurately detect bleeding in the brain of stroke patients. The goal is to speed up diagnosis and treatment by avoiding extra trips to the regular CT scanner. 252 adults with stroke symptoms were enrolled …

This study looked at whether a special eye scan (SS-OCTA) can detect signs of cardiovascular disease. Researchers compared retinal blood vessel changes to results from a standard carotid ultrasound in 42 adults. The goal was to see if the eye scan could predict the presence or se…

This study looked at whether a special type of CT scan (dual-energy CT) can more accurately tell the difference between bleeding and harmless contrast dye in the brains of stroke patients after treatment. About 189 adults who had a stroke and received clot-busting drugs or a clot…

This study tested a computer program called Heuron CTA that looks at brain CT scans to find large blockages in blood vessels. Researchers compared the software's results to diagnoses made by medical experts using scans from 270 adults. If accurate, this tool could help doctors di…

This study tested a device called NIRSITX that uses light to measure oxygen levels in the brain. Researchers compared oxygen readings from the injured side of the brain to the healthy side in 35 adults who had a stroke within the past week. The goal was to see if the device could…

This pilot study tested whether special magnifying goggles (Frenzel lenses) and a step-by-step diagnostic algorithm help emergency doctors better detect nystagmus—a telltale eye movement—in patients with sudden vertigo. The goal is to improve diagnosis of stroke versus benign inn…

This study tested whether a special ultrasound of the eye's main artery can help doctors diagnose increased pressure inside the skull. Researchers measured blood flow in the central retinal artery of 66 patients with stroke or traumatic brain injury. The goal was to see if change…

This study tested a new thinking test called CASP for stroke patients. The test is designed to work even for patients who have trouble speaking after a stroke. Researchers checked how well the test works by comparing it to other tests in 263 patients.

This study tested a new way to position the weak arm in stroke patients to prevent shoulder pain, a common problem that can slow recovery. 76 people who had a stroke within the last 48 hours took part. The program used special supports and slings, along with training for patients…

This study tested a drug called conestat alfa in 141 people undergoing a minimally invasive heart valve replacement (TAVI) for severe aortic stenosis. The goal was to see if the drug could reduce the risk of small strokes and kidney damage that can happen after the procedure. Par…

This study looked at how often older adults with heart disease risk factors should exercise to improve fitness and blood pressure. Twenty-two participants did combined training either twice or three times a week for 12 weeks. The goal was to see which frequency worked better for …

This completed clinical trial tested a procedure called ischemic postconditioning to prevent brain damage in 40 people undergoing carotid surgery for severe artery narrowing. The procedure involves briefly clamping and unclamping the carotid artery in cycles after surgery to prot…

This study tested a fall prevention education program for people who had a stroke more than six months ago. The program was based on the Health Belief Model and included two in-person sessions. Researchers compared the program to usual care in 44 participants to see if it improve…

This study looked at whether a simple oral hygiene routine could prevent a serious lung infection called aspiration pneumonia in people hospitalized after a stroke. Researchers compared 90 stroke patients who received structured mouth care from nurses to similar patients who got …

This study tests whether a technique called flossing (using a stretchy band around the shoulder) can reduce pain, improve movement, and help sleep in people who have had a stroke and have shoulder pain. About 40 adults aged 30-55 who are at least 6 months post-stroke will take pa…

This study tested a robotic hip exoskeleton designed to improve walking in people who had a stroke at least six months ago. Twelve participants walked on a treadmill and over ground with and without the device. The main goal was to see how well the exoskeleton's computer predicte…

This study tested whether fast arm movement training helps people who had a stroke regain arm function better than standard accuracy training. 44 chronic stroke survivors with mild to moderate arm weakness participated. The training focused on moving quickly, and researchers meas…

This study tested whether adding virtual reality-based mirror therapy or electrical stimulation-assisted cycling to standard rehab helps stroke survivors regain arm function better than rehab alone. Sixty adults who had a stroke within the past six months took part in a four-week…

This pilot study tests a home-based rehabilitation program called TASSRET for stroke survivors who have limited access to physiotherapy. Fifty participants will use either a video or a manual guide to practice specific tasks aimed at improving arm and leg function, balance, and q…

This study tested whether adding mental practice of swallowing to standard therapy helps people who have trouble swallowing after a stroke. 43 adults were split into three groups: one watched swallowing videos then imagined the action, one just imagined swallowing, and one had on…

This study tested a new occupational therapy program called PRO-MAMA for older mothers (70+) who have had a stroke. The program focuses on helping them take part in meaningful activities related to their role as a mother. Fourteen women completed the program, and researchers meas…

This study tested a new occupational therapy called HABIT, designed to help stroke survivors use their affected hand more in everyday activities. Eleven adults with mild hand weakness after stroke participated. Researchers measured hand use and satisfaction with daily tasks befor…

This study tested whether adding augmented cues—like visual and auditory feedback from a sensor-based glove—to standard physical therapy could improve hand function in people recovering from a stroke. Fifty patients with subacute ischemic stroke were randomly assigned to receive …

This study compared two non-invasive therapies—radiofrequency (TECAR) and ultrasound—for treating shoulder pain in 45 stroke survivors. Participants had shoulder pain for at least 3 months after their stroke. Researchers measured pain, range of motion, and daily function to see w…

This study tested a treatment that shines a laser light inside a vein to help people recover after an ischemic stroke. 22 adults with mild to moderate stroke symptoms received the laser therapy. Researchers measured their disability and stroke symptoms before treatment, and again…

This study looked at how two types of arm exercises—open and closed kinetic chain activities—affect muscle tightness and hand skill in people who had a stroke. Thirty stroke survivors with arm weakness did one type of exercise, and their muscle stiffness and dexterity were measur…

This study tested whether wearing a pressure splint on the leg during rehab exercises helps stroke patients with one-sided weakness (hemiplegia) improve leg movement, balance, and strength. Thirty participants were split into two groups: one did exercises with the splint, the oth…

This study looked at whether giving a sour liquid early on can improve swallowing function in people who have trouble swallowing after a stroke. Researchers worked with 95 patients who had an acute ischemic stroke and developed dysphagia. They measured swallowing ability at the s…

This study tested whether task-oriented gait training combined with core stabilization exercises can improve mobility, balance, and walking in people who had a stroke. Fifty-four adults aged 45-75 with left-side weakness took part in an 8-week program. The goal was to see if thes…

This study tested a nurse-led home care guide for stroke patients to help with daily activities. The goal was to see if the guide could reduce the burden on caregivers and improve their quality of life. The study involved 60 caregivers of stroke patients who were cared for at hom…

This completed study tested whether combining a gentle brain stimulation technique (HD-tDCS) with virtual reality therapy could help people who had a stroke more than three months ago recover arm function. Fifty-eight participants received either real or sham stimulation during V…

This study tested a personalized brain stimulation technique called iTBS to help people with long-term thinking and memory problems after a stroke. Sixty participants received either real or sham stimulation over three weeks. The goal was to see if this approach could safely impr…

This study tested a mobile robot designed to help people who have had a stroke regain their ability to walk. 37 stroke survivors used the robot for 16 sessions along with their usual physical therapy. The goal was to see if the robot improved their balance and walking more than s…

This study tested two different therapies—mirror therapy and action observation therapy—to see which better helps chronic stroke survivors improve arm movement and quality of life. 76 participants received one of the therapies plus standard physiotherapy for six weeks. The goal i…

This study tested whether adding foot pressure feedback to robot-assisted walking training helps improve walking symmetry and balance in people who have had a stroke and have weakness on one side. Sixteen adults with chronic hemiplegia completed a 4-week program using a Lokomat r…

This study tested whether a 24-session program of functional electrical stimulation (FES) on the tibial nerve could improve walking in people who had a stroke more than a year ago. Fifteen participants with chronic stroke and leg weakness were enrolled. The main goal was to see i…

This study tested whether a nature-based walking program called GREEN Walk can improve quality of life for people who have had a stroke. Eleven chronic stroke survivors took part in 60-minute sessions walking on grass, slopes, and uneven ground to mimic real-world movement. Resea…

This study tested whether combining somatotherapy (body awareness and movement exercises) with occupational therapy (training in daily tasks like dressing and cooking) could improve cognitive function in 50 adults who had a stroke. Participants received 35-minute sessions five da…

This study looked at whether percussion massage therapy (like using a massage gun) can help people who had a stroke more than 6 months ago. 34 adults with leg stiffness and trouble walking took part. The goal was to see if the massage could reduce muscle tightness and improve wal…

This study looked at whether electroacupuncture (a type of acupuncture with mild electric pulses) can lower inflammation and help people recover after a stroke. 17 adults who had their first ischemic stroke took part. Researchers measured changes in symptoms and blood markers to …

This study tested whether a chin tuck against resistance (CTAR) exercise can improve swallowing in stroke patients with dysphagia. 112 participants did the exercise daily for two weeks alongside standard rehab. Researchers measured swallowing ability with a water test and a quali…

This early-stage trial tested a new oral drug called MTR-601 in 89 healthy adults to see if it is safe and how the body processes it. The drug aims to reduce muscle stiffness and spasms, which could help people with conditions like cerebral palsy, multiple sclerosis, or stroke. S…

This study tested whether adding gentle sensory stimulation (like light touch and tapping) to standard physical therapy could improve facial symmetry and function in people with facial palsy after a stroke. Thirty-six participants were split into two groups: one received both sen…

This study tested two therapies—mirror therapy and PNF techniques—to see if they improve leg movement and balance in people who had a subacute stroke. 36 participants aged 40-65 were split into two groups, each receiving one therapy along with standard exercises. The goal was to …

This pilot study tested a wearable grasping neuroprosthesis in 6 people with hand weakness after a stroke. Participants used the device at home daily to help with gripping tasks. The study focused on how often people used it and whether it was practical and helpful in real life.

This study looked at two methods to reduce pain after heart surgery through a cut in the chest bone. 120 adults received either a nerve block near the breastbone, pain medicine injected into the wound, or standard painkillers. Researchers measured pain levels using a saliva test …

This study looked at 39 adults who had arm stiffness (spasticity) after a stroke. Researchers compared different types of transcranial magnetic stimulation (TMS) combined with Botox injections to see which worked best. The goal was to reduce muscle tightness and improve arm movem…

This study tested a device that gently stimulates nerves in the head and neck to help people who had a stroke move their arm better. Sixteen adults who had a stroke at least six months ago used the device during rehabilitation. The goal was to see if the device is safe and if it …

This study tested a soft robotic glove called EsoGLOVE to help stroke patients improve hand movement and strength during inpatient rehab. 61 stroke survivors used the glove for at least 30 minutes a day, five days a week, for three weeks. The goal was to see if the glove could as…

This study tested whether combining intense arm training with electrical muscle stimulation and brain stimulation could improve arm function in 20 chronic stroke survivors who had severe hand paralysis for more than 6 months. Participants received both types of brain stimulation …

This study tested whether draining some fluid from the spine (a lumbar puncture) can help relieve severe headaches that often follow a brain aneurysm rupture. The trial involved 74 patients with mild to moderate brain bleeds. Half received a real lumbar puncture, and half receive…

This study tested whether a quick, precise push on the upper back (thoracic spinal manipulation) can improve balance and reduce fall risk in people who had a stroke at least 6 months ago. Sixty participants received either the real manipulation or a placebo version. Researchers m…

This study tested whether a gentle brain stimulation technique called tDCS, combined with health education and aerobic exercise, can help reduce fatigue in people who have had a stroke. 54 participants who had a first stroke within the past 45 days and reported significant fatigu…

This study tested a new walking therapy for people who had a stroke at least 6 months ago. A robotic device was used to amplify the person's own leg movements during walking, aiming to improve balance. 33 participants completed the training, and researchers measured changes in wa…

This study tested a new memory training program for people who have memory problems after a brain injury (like a stroke or head injury). Six participants either received standard treatment or a shorter program that included a special memory game to practice at home. The goal was …

This study tested whether using a mirror to create the illusion of movement in a paralyzed arm can improve function in people who had a stroke within the past month. 49 participants were split into three groups: one did mirror therapy with only the good arm moving, another moved …

This study tested three types of hand exercises in 81 people who had a stroke: sensory exercises, motor exercises, and a combination of both. The goal was to see which approach best improved hand strength, dexterity, and reaction time. Results suggest that combining sensory and m…

This study tested whether a virtual reality shopping game could help stroke survivors improve their daily living skills. Twenty-nine adults who had a stroke 1 to 18 months earlier participated. One group practiced shopping in a virtual supermarket, while the other did standard co…

This study tested whether a breathing exercise using an Ambu-bag (air stacking) can improve lung function and trunk control in people who had a stroke. Twenty stroke survivors did either the air stacking breathing exercise or standard diaphragmatic breathing, three times a week f…

This study tested two non-drug therapies—graded motor imagery (mental rehearsal) and mirror therapy (using a mirror to trick the brain)—in 44 chronic stroke patients aged 45 to 65. The goal was to see which better reduces muscle spasticity and improves independence. Both therapie…

This study tested whether stroke survivors could use non-immersive virtual reality exercises at home to improve arm function and balance. Twenty-seven people with chronic stroke (more than 6 months since their stroke) participated in an 8-week program. The exercises were designed…

This completed trial looked at how two different feeding tubes affect the mental health of 156 stroke patients with swallowing problems. One group used a standard nasogastric tube, the other an intermittent oro-esophageal tube. Researchers measured anxiety, depression, and feelin…

This pilot study tested whether adding virtual reality (VR) exercises to standard rehabilitation helps people who recently had a stroke recover their thinking skills and ability to do daily tasks. Thirty-six adults with acute stroke and mild cognitive impairment were assigned to …

This study tested whether adding a gentle brain stimulation technique called tDCS to a reading therapy (PMT) could help stroke survivors with aphasia read better. Six people with chronic aphasia took part. The goal was to see if the combination improved reading accuracy more than…

This study tested whether combining focal muscle vibration (gentle muscle shaking) with transcranial direct current stimulation (a mild brain current) could help stroke survivors move better and reduce muscle tightness. Sixty people with chronic stroke received these treatments a…

This study tested whether a gentle, non-invasive brain stimulation technique called tDCS could reduce depression and improve thinking in people who had a stroke. Sixty participants received either tDCS or breathing exercises over eight weeks. The goal was to see if tDCS could be …

This study tested whether chewing real food (like candies and dumplings) before meals can improve swallowing and quality of life in stroke patients who have trouble swallowing. 120 patients were split into two groups: both got standard rehab and tube feeding, but one group also c…

This study tested whether adding functional electrical stimulation (FES)-assisted cycling to standard rehab helps stroke survivors with Complex Regional Pain Syndrome (CRPS). Forty participants either received FES cycling plus conventional therapy or conventional therapy alone fo…

This completed trial tested an 8-week program called Healing Hearts Together (HHT) for couples where one partner has heart disease. 474 couples attended weekly group sessions focused on communication, emotional support, and heart health. The goal was to see if the program improve…

This study tested a simple, non-invasive procedure called ischemic conditioning in 132 chronic stroke survivors. The procedure involves inflating a blood pressure cuff on the affected leg to briefly stop blood flow, then releasing it, repeated several times. Researchers measured …

This study tested whether a device that assists hand opening and a robot that supports the shoulder can help stroke survivors with moderate to severe arm weakness practice daily activities. 53 participants completed the trial. The goal was to see if this device-assisted practice …

This study tested a gentle, non-invasive brain stimulation technique called tDCS in 14 people who had a stroke at least a year ago and still have trouble finding words (aphasia). The goal was to see if stimulating a key language area could improve their ability to name pictures a…

This study tested low-level laser therapy (LLLT) on 18 chronic stroke patients with ankle stiffness. Half got laser plus physiotherapy, half got physiotherapy alone for three weeks. Both groups improved, but the laser group had greater reductions in muscle tightness and better wa…

This study looked at whether adding robot-assisted walking training to stationary cycling helps people who recently had a stroke and are losing muscle. 53 participants did either cycling alone or cycling plus robot walking for 4 weeks. The goal was to see if the combination impro…

This study tested whether a set of exercises called FAST (Fast muscle Activation and Stepping Training) can improve walking balance in people who had a stroke. 55 participants who had a first stroke within the past 6 months and had leg weakness took part. They did 12 sessions of …

This study tested whether combining repetitive transcranial magnetic stimulation (rTMS) with motor training helps stroke patients regain arm function. 60 participants were split into three groups: online rTMS during training, offline rTMS before training, or sham stimulation. The…

This small proof-of-concept study tested a non-invasive device that uses sound and light to help people with hemianopia (blindness in half of the visual field). Five adults with stable hemianopia underwent training sessions where they were exposed to matching sound and visual cue…

This study tested whether 3 weeks of intensive language therapy (at least 2 hours daily, 5 days a week) helps people with long-term aphasia after a stroke communicate better in everyday situations. 156 participants with aphasia for at least 6 months were assigned to either immedi…

This study looked at whether using magnetic stimulation on the arm before a specific type of physical therapy helps people who had a stroke regain better use of their affected arm and hand. 50 participants were included. The approach aims to improve wrist movement and daily activ…

This study tested whether adding seated vibration training to standard rehab could help people who had a stroke at least six months earlier. Over four weeks, 39 participants received vibration training plus usual care. Results showed improvements in leg strength on the unaffected…

This completed trial tested whether brief, moderate-to-vigorous physical activity sessions combined with health education could increase exercise in stroke survivors. 36 adults aged 50 and older who had a stroke and lived at home took part. Participants wore an accelerometer to t…

This study tested whether playing virtual reality games could help people who had a stroke more than 6 months ago improve arm movement. 15 chronic stroke patients with arm weakness participated. They used a head-mounted VR device to do exercises. The goal was to see if this fun, …

This study tested a powered hip exoskeleton for gait training in 32 people who had a stroke at least 3 months earlier. Participants used the device for 10 sessions over 5 weeks. The main goal was to check safety and see if walking speed improved.

This study tested whether vibration training can help people who recently had a stroke improve leg muscle strength, daily function, and mood. 148 patients took part. The approach uses whole-body vibration to stimulate muscles, aiming to speed recovery after a stroke.

This small pilot study tested whether a brain-computer interface (BCI) that gives real-time feedback during mental practice could improve arm function in people who had a stroke at least a year ago. Seven participants did mental imagery exercises with or without real brainwave fe…

This study tested whether robot-assisted arm therapy works as well as traditional therapy with a physiotherapist for people recovering from a stroke. 58 adults who had a stroke within the past 6 weeks took part in a 6-week program doing the same arm exercises, either with a robot…

This study tested a device called MyoRegulator® to see if it can reduce muscle stiffness (spasticity) in the lower leg after a stroke. 44 adults who had a stroke at least 6 months earlier took part. Half received real treatment and half received a sham (fake) treatment for 5 days…

This study tested the safety and effectiveness of repeated MYOBLOC injections over one year in 187 adults with troublesome drooling caused by conditions like Parkinson's disease, stroke, or ALS. Participants received up to four treatment sessions, and researchers tracked side eff…

This Phase 3 study tested whether injections of MYOBLOC (a botulinum toxin type B) into the salivary glands can safely reduce troublesome drooling in adults. 187 participants received either MYOBLOC or a placebo. The main goals were to measure changes in saliva flow and overall i…

This study tested whether a non-immersive virtual reality system (MindMotion GO) could help people with chronic stroke improve arm function better than standard occupational therapy. Twenty-six adults who had a stroke more than 6 months ago participated in 8 weeks of training. Th…

This study tested a new program called CATCHES for people who had a stroke and are afraid of falling. The program combines physical therapy at home with coaching to reduce fear. 30 adults who had a mild to moderate stroke took part. The goal was to see if the program is practical…

This study tested a tablet-based app that helps people recovering from stroke improve coordination between both arms. 40 participants with moderate arm weakness used the app to practice moving their arms together in rhythm. The goal was to see if this fun, at-home style training …

This study tested whether a 20-minute session of nurse-led spiritual care, including prayer and relaxation techniques, could help heart surgery patients feel less anxious and have more stable blood pressure and heart rate before their operation. 248 adults in Indonesia took part.…

This study tested a device called recoveriX that uses a brain-computer interface, electrical stimulation, and virtual reality to help stroke survivors improve their walking. Thirty participants who had a stroke at least six months ago were split into two groups: one used the full…

This study tested a device called IpsiHand that helps people who had a stroke regain movement in their arm and hand. The device reads brain waves through a special cap and moves the hand using a robotic brace. 24 stroke survivors used it for 12 weeks to see if it improved their m…

This study tested whether mirror therapy can reduce pain and improve movement in stroke patients who also have complex regional pain syndrome (CRPS). Forty adults who had a stroke within the past year and were diagnosed with CRPS took part. They received either real mirror therap…

This study tested two methods to help people regain arm movement after a stroke: looking at a mirror to trick the brain, or using a robotic hand glove that mimics the healthy arm. Thirty adults who had a stroke within the past year took part. Both groups also received standard ph…

This study tested whether adding a drug called Cytoflavin to standard physical rehab helps stroke survivors recover better. Cytoflavin is an antioxidant that may protect brain cells and improve learning of new skills. The trial involved 240 adults aged 40-80 who had a stroke 2 we…

This study tested whether combining neuromuscular electrical stimulation (gentle electrical pulses to muscles) with task-oriented training (practicing everyday movements) could improve arm and hand function in stroke survivors. 45 people who had a stroke 6 to 24 months earlier to…

This study tested whether people with spinal cord injuries can reach a high-intensity heart rate while walking in a robotic exoskeleton. Eleven participants completed five training sessions using the Ekso device. Researchers measured heart rate, walking speed, and endurance befor…

This study tested whether a virtual reality-based treadmill program could improve walking in people who had a stroke within the last 6 months. Thirty participants with mild to moderate walking problems took part. The training used a 2D camera to measure steps, stride length, and …

This study tested a program called SIESTA-Rehab to help stroke patients sleep better during their hospital stay. The program included training nurses to reduce nighttime disruptions and a plan to check for and treat sleep apnea. Researchers studied 400 adults in a rehab hospital …

This study tested a non-invasive treatment called shock wave therapy on 21 stroke survivors with arm stiffness. The therapy uses sound waves to relax tight muscles. Participants received 8 sessions over 4 weeks, and researchers checked for improvements in stiffness, pain, and dai…

This study tested a myoelectric computer interface (MyCI) in 35 stroke survivors to reduce abnormal muscle co-activation. Participants trained with the device in a lab setting. The goal was to improve arm function and reduce muscle tightness. Results may help develop new therapie…

This study tested whether a robotic exoskeleton called Ekso can help stroke patients improve their walking and balance during early inpatient rehabilitation. Forty adults who had a stroke were randomly assigned to receive either Ekso-assisted gait training or conventional therapy…

This study tested a non-invasive brain stimulation technique called continuous theta-burst stimulation (cTBS) in 60 people who had a stroke within the past two weeks and had moderate to severe arm weakness. The stimulation was guided by brain scans to target areas involved in mov…

This study tested whether combining motor imagery (thinking about moving without actually moving) with a type of brain stimulation called TMS could help people who had a stroke regain arm function. 24 adults who had a stroke at least one month prior participated. The goal was to …

This study tested a metacognitive strategy training for 45 stroke survivors who have trouble paying attention to one side of their world (called neglect). The training aimed to improve their self-awareness and ability to do daily tasks. Results will show if this approach reduces …

This study tested whether combining a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) with balance exercises could improve walking in people who had a stroke. Thirty stroke survivors, aged 50 to 60, participated. Researchers measured change…

This small pilot study tested whether a gentle electrical current applied to the brain (tACS) could improve naming ability in 11 people with chronic aphasia after a stroke. Participants received either real or sham stimulation during language training over two weeks. The goal was…

This study tested whether a 15-minute session of rhythmic beats (like a metronome) before standard physiotherapy could improve balance and weight shifting in stroke patients. 27 participants were split into two groups: one received the beats plus usual therapy, the other only usu…

This study tested whether specialized sexual nursing care could help stroke patients and their partners manage sexual difficulties. Thirty stroke survivors and their partners were split into two groups: one received personalized counseling and education from trained nurses, while…

This study tested a new rehab method for people who had a stroke at least 6 months ago and still have hand weakness and stiffness. The approach combined a drug called cyproheptadine with active movement practice to help improve voluntary muscle control and strength. 96 participan…

This study tested whether combining a brain-training app (Lumosity) with stationary bike exercise could improve thinking skills and quality of life in people who had a stroke. Twenty-two adults with mild to moderate cognitive problems after a stroke took part. The experimental gr…

This study tested whether combining lower-body power exercises with fast walking training can improve mobility in people who had a stroke at least six months ago. Sixty adults aged 18 to 75 took part in a program three times a week. Researchers measured how quickly they could sta…

This study looked at whether starting more frequent or intense physical therapy within the first day after a stroke helps patients regain movement and balance. 102 adults with acute stroke were split into groups receiving standard care, more sessions, harder exercises, or both. R…

This study tested whether a device that sends magnetic pulses to shoulder muscles can help stroke patients with a dislocated shoulder. Twenty people in the subacute phase of stroke received either real or fake magnetic stimulation for 20 minutes a day, 5 days a week, for 2 weeks,…

This study tested whether a device that uses sound vibrations and laser-guided motion could help stroke survivors improve their balance and sensory integration. 44 adults aged 45-60 who had a stroke at least 6 months earlier participated. The therapy aimed to retrain the brain's …

This study tested a special video game controlled by muscle signals (EMG) to help people who had a stroke at least 6 months ago improve hand movement. Twenty participants with moderate hand weakness played the game using either one hand or both. The goal was to see if this fun tr…

After a stroke, many people struggle to open their affected hand. This study tested two types of electrical stimulation—one that cycles on and off automatically, and another that is controlled by the good hand—plus standard occupational therapy. 132 stroke survivors took part to …

This study tested whether adding virtual reality (VR) balance games to standard physical therapy helps people who had a stroke and have weakness on one side (hemiplegia). 43 patients were split into two groups: one got regular therapy plus VR balance exercises, the other got regu…

This pilot study tested a new robot-based therapy program to improve arm function in 10 people who had a stroke at least 6 months ago. The program combined robot-assisted training, practice with daily activities, and home exercises over 4 weeks. The goal was to see if the approac…

This small study tested whether a noninvasive electrical stimulation device placed on the skin over the spinal cord could help people who have trouble walking after a stroke. Eight participants received either spinal stimulation plus gait training or gait training alone. The goal…

This study tested whether combining time pressure motor training with step square exercises could improve decision-making and quality of life in stroke survivors. Thirty-eight participants who had a stroke more than three months ago took part. The training aimed to help them thin…

This study looked at whether listening to self-chosen Italian music during and after a stroke hospital stay can improve mood, reduce anxiety and depression, and boost overall well-being. 150 stroke patients were randomly assigned to either regular music listening or standard care…

This study tested whether Liuzijue Qigong, a traditional Chinese breathing exercise, could improve lung function in elderly people who had a stroke. 70 participants did either Qigong or standard rehab for 12 weeks. Researchers measured breathing capacity, walking ability, and qua…

This study tested whether using an immersive virtual reality (VR) headset along with practice of everyday arm tasks could improve arm movement in people who had a stroke at least 6 months earlier. 13 adults with limited arm motion took part. Their arm movement was measured before…

This completed study tested whether adding cognitive training and rhythmic auditory stimulation to treadmill walking improves walking automaticity, executive function, and dual-task coordination in people with chronic stroke. Eighty participants were assigned to one of four group…

This study tested a device that combines mild electrical muscle stimulation with a balance-board video game to help people with spinal cord injury or stroke improve their balance and reduce fall risk. 18 adults who were at least one year past their injury took part. The goal was …

This study tested a modified training program that combines watching movements, imagining movements, and doing exercises to help stroke survivors improve arm function. 46 people who had a stroke within the past 1 to 6 months took part. The goal was to see if this approach could i…

This study tested whether using a video game called MindPod Dolphin is safe and practical for arm rehabilitation in people who recently had a stroke. 58 participants played the game, controlling a dolphin with their affected arm. The goal was to see if patients would stick with i…

This study tested whether the Ghostly app, which guides patients through strength exercises, could help hospitalized people with stroke, COVID-19, frailty, or muscle weakness. Fifteen participants used the app during their hospital stay. The goal was to see if it was practical an…

This study tested a new rehab system called Rehabotics that uses a robotic hand aid and augmented reality games to help people who had a stroke regain hand movement and reduce muscle tightness. 80 stroke survivors with hand spasticity took part. The system tracks progress and aim…

This study tested whether combining a drug called galantamine with a specific cognitive training program could improve thinking skills in adults aged 35-70 who had a first stroke 3 months earlier. 47 participants received either the drug or a placebo, plus brain training, and wer…

This study tested an app called iTalkBetter for people who have trouble finding words after a stroke. 31 participants used the app to practice naming specific items. The goal was to see if the app could improve word retrieval for those practiced items. This small trial helps unde…

This study tested whether increasing the amount of arm training helps people who had a stroke regain arm function. Twenty stroke survivors were split into two groups: one did 3 hours of training per week for 4 weeks, the other did 10 hours per week. Both groups used a robotic arm…

This study tested whether adding a special balance-training device to standard rehab helps people who had a stroke at least six months ago. The device uses a platform that gives real-time visual feedback as the person shifts their weight. Thirty-six participants were split into t…

This study looked at whether nicergoline, a drug that improves blood flow in the brain, can help people with swallowing problems caused by stroke, Parkinson's disease, or dementia. 92 adults were given either a low or high dose for 12 weeks. The goal was to see if swallowing impr…

This study tested whether wearing custom-made insoles for six weeks could improve foot alignment, body alignment, and balance in chronic stroke patients. Twenty participants over age 50 were split into two groups: one wore the insoles during daily activities plus standard physica…

This study tested whether a 3-month yoga program could improve physical and mental health in adults over 65 who had recently finished cardiac rehab. Participants attended yoga twice a week. Researchers measured balance, muscle strength, anxiety, and mood. The goal was to see if y…

This study tested two ways to do extra arm exercises after a stroke: a custom program designed by a therapist, or using a special movable wheelchair armrest (called Boost). 35 people in acute rehab took part. The goal was to see which method better improves arm movement and reduc…

This completed study tested the EXOPULSE Mollii suit, a full-body garment with 58 electrodes, in 30 stroke survivors who had muscle stiffness (spasticity) and balance problems. The suit stimulates muscles to reduce spasticity and improve balance. Researchers measured balance chan…

This study tested whether a gentle electrical current applied to the scalp (tES) can improve movement and thinking in people who had a stroke. Sixty adults who had a stroke between 2 weeks and 2 years ago received real or fake stimulation while doing physical therapy. Researchers…

This study tested a robotic system called Harmony SHR to help people who had a stroke and have trouble moving one or both arms. The robot assists with shoulder and arm movements during rehab. The goal was to see if it is safe, reliable, and helpful for improving arm function. The…

This small study tested whether a gentle electrical current applied to the scalp (tDCS) can improve arm movement in people who had a stroke at least 6 months ago. 11 participants received either real or fake stimulation along with standard hand and arm therapy for 20 sessions. Re…

This study looked at whether adding a 15-minute vibration treatment to a standard arm skill program helps people who had a stroke 3-6 months ago. 60 participants were split into two groups: one got the vibration plus training, the other got training alone. Researchers measured ar…

This study looked at whether adding virtual reality (VR) balance exercises to standard physical therapy helps stroke patients walk and keep their balance better. 34 people who had a stroke within the last 6 months took part. Some did only standard therapy, while others replaced 2…

This study tested whether adding vibration to hand exercises helps stroke survivors regain hand function better than exercises alone. 61 adults who had a stroke at least 6 months prior participated. The main goal was to see if the vibration group could perform hand tasks faster a…

This study tested whether adding vibration therapy to standard rehabilitation could improve leg muscle strength, daily function, and emotional well-being in people who recently had a stroke. 115 hospitalized patients were randomly assigned to receive either standard care alone, s…

This study tested a Compensation-Based Problem-Solving Therapy in 52 stroke survivors to see if it improves their ability to perform daily activities, feel more confident, and enjoy a better quality of life. The therapy focuses on finding practical ways to work around stroke-rela…

This study tested whether online occupational therapy sessions could help stroke survivors improve their ability to perform everyday tasks like bathing, dressing, and using the phone. Fifteen patients on a waiting list for rehab were randomly assigned to receive remote guidance o…

This study tested a therapy where chronic stroke patients watch simple arm and hand actions on a screen and then imitate them. The goal was to see if doing this via video calls (telerehabilitation) works as well as doing it in person. 26 patients with left-side weakness took part…

This study tested whether adding virtual reality games to standard rehabilitation helps people who had a stroke improve arm function. Forty adults within one year of their first stroke participated. Results measured arm movement, daily activities, and participation levels.

This study tested whether a gentle, non-invasive brain stimulation called tDCS could make speech therapy work better for people with aphasia (trouble speaking or understanding language) after a stroke. 23 adults who were at least 6 months past their stroke received speech therapy…

This study tested two different treatments—neuromuscular electrical stimulation and electromyographic biofeedback—to see which better improves swallowing in people who had a stroke. 60 patients with moderate swallowing problems took part. The goal was to make eating and drinking …

This study tested whether adding mental practice (motor imagery) and a special tilt table (ErigoPro) to standard rehab could improve balance in people who had a stroke. 66 participants, 6-8 weeks after their stroke, took part. The goal was to see if these extra therapies help wit…

This study looked at 886 adults with suspected traumatic brain injury to better understand how the brain changes after injury. Participants had MRI scans, blood tests, and thinking tests within 48 hours of injury, with optional follow-ups up to a year. The goal was to find better…

This study explored how family members share health information about genetic diseases like sickle cell, diabetes, and cancer. Over 1,000 adults completed surveys or interviews about their family health history and support. The goal was to understand social and relational factors…

This study looked at 20 people with CADASIL, a rare genetic disease that damages brain arteries and causes migraines, strokes, and dementia. Researchers used blood tests, skin biopsies, eye exams, and brain scans to learn more about how the disease works. The goal was to better u…

This study investigates how different language treatments affect both language skills and brain function in people with aphasia, a condition that impairs the ability to speak, understand, read, or write after a stroke. Participants will receive therapy targeting naming, spelling,…

This study looks at medical records from France to see how doctors prescribe blood thinners to people with atrial fibrillation (an irregular heartbeat) who also have a high risk of stomach bleeding. The goal is to understand which treatments are used and how often serious bleedin…

This study aims to create a simple rule that emergency call handlers can use to predict whether an older adult (65+) who has fallen and hit their head is at risk of a brain bleed. Researchers will collect information from 1,100 calls to the SAMU emergency center in Toulouse, Fran…

This study aims to identify short-term triggers of acute ischemic stroke caused by large vessel occlusion, a severe type of stroke. Researchers will ask 302 patients about their exposure to potential triggers—such as infection, mood changes, smoking, alcohol, diarrhea, and extrem…

This study looked at why some people have trouble balancing while sitting after a stroke. Researchers used a special pressure-sensing pad and motion trackers to measure how 32 stroke survivors shifted their weight and moved their head and trunk. The goal was to better understand …

This completed study followed 81 adults who had stroke-like symptoms to see how damage to the blood-brain barrier relates to white matter changes in the brain. Over 6 years, participants had regular MRI scans and thinking tests. The goal was to better understand why some people d…

This study looked at whether brain scans (fMRI) can predict how well stroke survivors will recover arm and hand function after physical therapy. Fourteen people with chronic stroke completed 12 therapy sessions. Researchers measured brain connectivity before and after therapy to …

This study explores whether ultrasound can help evaluate swallowing difficulties in people who have had a stroke. Researchers will measure the size and movement of throat muscles in 52 stroke patients with swallowing problems. The goal is to see if these ultrasound measurements r…

This study tested whether a video call between paramedics and a stroke specialist can help decide the right treatment—like clot-busting drugs or clot removal—before the patient arrives at the hospital. About 215 adults with suspected stroke took part. The goal was to see if remot…

This study looked at over 30,000 adults admitted to hospitals in Maryland to understand why some patients wait in the emergency room even after being admitted (called boarding). Researchers wanted to find out what patient traits lead to longer waits, how boarding increases health…

This completed study looked at 140 stroke patients to understand what affects how long they stay in the hospital for rehabilitation. Researchers measured things like functional independence, balance, mental state, and depression in both patients and caregivers. The goal is to hel…

This study followed 67 children with sickle cell disease who had a high risk of stroke. Researchers compared those who received a bone marrow transplant to those who got standard care, checking brain scans and thinking skills 9-10 years later. The goal was to see which approach b…

This study tested whether a wearable sensor (Baiobit®) can reliably measure walking patterns in stroke survivors. Twenty-two adults who had a stroke walked with the sensor on their lower back, and two evaluators compared the results. The goal is to see if this low-cost device can…

This pilot study tested whether giving inhaled nitric oxide gas during laparoscopic surgery could protect blood vessels and organs in 40 adults with heart disease. Half received the gas through their breathing tube during surgery, and half received standard care. Researchers meas…

This study looked at whether a substance in the blood called D-dimer can help predict how well people recover after a stroke. Researchers measured D-dimer levels in 102 stroke patients who had received treatment to restore blood flow. They then compared these levels with standard…

This study looked at whether using best-practice physical therapy and giving stroke survivors an activity monitor can help them walk better. About 306 people who had a stroke and were in rehab took part. The main goal was to see if they could walk farther in 6 minutes after the p…

This study looked at hormone levels in 26 people within 48 hours of a brain bleed from a burst aneurysm. Researchers checked cortisol and thyroid hormones and did a stimulation test to see if the pituitary gland was working properly. They then tracked complications like rebleedin…

This completed study looked at 114 adults with a type of brain bleed called subarachnoid hemorrhage from a ruptured aneurysm. Researchers measured the optic nerve sheath on early CT scans to see if the size could predict whether a patient would survive for 6 months. The goal was …

This study tracked 883 adults with atrial fibrillation to see how consistently they took their direct oral anticoagulants (blood thinners). Researchers used pharmacy refill records and a simple questionnaire to measure adherence. The goal was to find patterns that could help iden…

This study tested whether a brain-computer interface (BCI) device is ready for commercial use to help people with minimal movement communicate. Researchers worked with 8 device users, plus speech therapists and support staff, to evaluate how well the device worked at home. The go…

This study tested whether a brain-computer interface (BCI) system, combined with electrical stimulation and virtual reality, can improve arm movement in chronic stroke survivors. Thirty participants were split into three groups, each receiving different combinations of BCI, elect…

This study tested whether a single, one-hour education session using the BEFAST mnemonic (Balance, Eyes, Face, Arm, Speech, Time) could improve stroke patients' knowledge and emergency response. Researchers enrolled 112 hospitalized stroke patients in Malaysia, measuring their kn…

This study tested a training program for 22 caregivers of stroke patients. The program taught basic stroke care, rehabilitation, and self-care. Researchers measured changes in caregiver knowledge, strain, and quality of life before and after the training. The goal was to see if t…

This study tested a new, powerful MRI scan on 56 stroke patients to see if it could detect subtle brain damage not visible on standard scans. The goal was to better understand how much brain tissue is truly saved after treatment. The findings could help doctors predict recovery m…

This study tested a 4-hour head ultrasound (transcranial-holter) to detect tiny blood clots in people who recently had a stroke. The goal was to see if this test could help doctors find the exact cause of the stroke, which is important for choosing the right treatment to prevent …

This study tested whether daily mood check-ins via a mobile app could help predict and prevent depression in people who recently had a stroke. Over 400 participants used the app for three months while researchers tracked their emotional symptoms. The goal was to see if this kind …

This study looked at how activating two key core muscles—the transversus abdominis and lumbar multifidus—affects balance in 36 people with hemiplegia (paralysis on one side) after a stroke. Researchers measured balance using standard tests like the Berg Balance Scale. The goal wa…

This study looked at 150 Caribbean Hispanic adults with heart disease or stroke risk who take the blood thinner clopidogrel. Researchers wanted to see if certain gene variants affect how well the drug works. The goal is to understand why some people get less benefit and to pave t…

This completed study looked at how rising temperatures affect people with chronic conditions like heart disease, diabetes, and depression. Researchers in Germany and Italy surveyed 176 patients to see what symptoms they experienced during heat and what protective steps they took.…

This small pilot study tested whether a non-invasive eye scan called OCTA can detect changes in the brain related to stroke and other neurological conditions. Researchers compared eye scans from 7 people with brain diseases and healthy volunteers. The goal was to gather early dat…

This study tested a wearable device called the MOX activity monitor in 40 older adults (70+) recovering from hip fracture, stroke, or frailty in a hospital rehab ward. The goal was to measure how much they walk, stand, or sit during the day and see if that data helps track recove…

This completed study tested a smart wearable device called gaitQ that monitors and cues walking in people with long-term movement conditions like Parkinson's, stroke, multiple sclerosis, and arthritis. Researchers collected movement data from 98 participants in a lab to see if th…

This study looked at 70 people who had a tissue heart valve replacement. It compared two common blood-thinning treatments (high-dose aspirin alone vs warfarin plus low-dose aspirin) to see which one better prevented tiny blood clots from traveling to the brain. Researchers used u…

This study tested a technique called ischemic conditioning, where a cuff around the thigh briefly restricts blood flow, to see if it can improve brain activity and leg function in people who had a stroke. Twenty participants with a stroke at least six months prior completed two s…

This study checked how well over 5,000 heart patients follow their prescribed medicine routine. Researchers asked patients about their medication habits and any side effects. The goal was to understand how many patients do not take their medicines as directed.

This completed study looked at 192 adults with acute ischemic stroke to see if large swings in blood sugar (glycemic variability) are linked to worse outcomes, including death and disability. Participants wore a continuous glucose monitor for 96 hours. The goal was to understand …

This study tested a tool called the TriAGE+ score to see how well it predicts stroke risk in 818 emergency room patients with dizziness. Dizziness can be a sign of a stroke, but it is often missed. The goal was to check if the score is safe and reliable for use in busy ERs to hel…

This completed study looked at insurance claims data from 70,000 people with type 2 diabetes and established heart disease to compare the heart-related risks of three diabetes drugs: tirzepatide, dulaglutide, and semaglutide. The goal was to see if any of these drugs was linked t…

This study tested two advanced rehabilitation devices—a treadmill and an overground walking trainer—to help 80 stroke patients regain their ability to walk. Participants used either the C-Mill treadmill or the Andago overground device alongside standard therapy. The goal was to s…

This study looked at 38 people who had a first stroke in the cerebellum, a brain area involved in mood. Researchers used interviews and smartphone tracking to measure depression, anxiety, and apathy in daily life. The goal was to better understand how these mood problems develop …

This study tested whether a gentle, non-invasive brain stimulation technique called tACS could improve hand function in 20 stroke survivors. The stimulation targeted two key brain areas involved in movement planning. Researchers measured brain connectivity and hand movement patte…

This completed study followed 550 people who had a stroke within the last 48 hours. Researchers wanted to understand why some patients recover better than others by looking at their medical history, lifestyle, and blood markers. The goal is to find out what factors protect the br…

This study tested whether an online training program can effectively teach healthcare workers to screen stroke patients for swallowing problems (dysphagia). Swallowing difficulties affect about 55% of stroke patients and increase pneumonia risk. The study involved 82 healthcare p…

This pilot study tested a new rehabilitation approach called early motor-cognitive integrative training (e-MCIT) in 6 patients recovering from a brain aneurysm bleed. The training combines thinking exercises with physical movement in 30-minute sessions, done 4-5 times a week unti…

This study tested a new plate imaging system to measure how much food stroke patients eat in the hospital. Fifty patients on a stroke rehabilitation ward had their meals photographed to estimate calorie and nutrient intake. The goal was to see if this simple, non-invasive method …

This study looked at how well an augmented reality app (Rehabilitation Gaming System) can mimic standard therapy exercises for arm movement after a stroke. 28 people (16 healthy older adults and 12 stroke survivors) performed both therapy exercises and app-based games while weari…

This study translated the Fugl-Meyer assessment, a test that measures movement and function after a stroke, into Turkish and checked if it works correctly. Researchers tested 80 stroke patients in Turkey to see if the Turkish version is reliable and accurate. The goal was to give…

This study looked at how a stroke survivor's sense of body position (proprioception) relates to their walking, balance, and reaction time. Researchers tested 132 first-time stroke patients and compared them to healthy volunteers using standard tests and rehabilitation robots. The…

This study asked stroke survivors, caregivers, and healthcare professionals what they need from a home-based rehabilitation system called NEST. The system includes an exercise app, a smartwatch, and a virtual coach. Researchers held focus groups and interviews in Italy, Spain, an…

This study tested a new robotic device called REACTION that combines an exoskeleton and a gait trainer to help people with stroke or spinal cord injury improve walking and balance. Seven participants completed two sessions of walking and balance tasks, followed by an interview. T…

This study tested whether a special PET scan can predict delayed brain damage in people who had a bleeding stroke from a burst aneurysm. 35 participants received a PET scan within days of their stroke to measure how their brain cells take up sugar, which reflects blood flow. The …

This study tested different levels of stiffness in custom ankle braces for 40 people who had a stroke. The goal was to find the best brace for each person and create simple guidelines that doctors and therapists can use to prescribe the right brace. Participants walked with five …

This study observed 141 people in German stroke units who had a brain bleed while taking the blood thinners rivaroxaban or apixaban. Researchers wanted to see if giving the reversal drug andexanet alfa could stop the bleed from getting bigger. They tracked changes in bleed size o…

This pilot study tested a web-based tool designed to improve communication and decision-making between doctors and families of patients with severe acute brain injuries, such as stroke or traumatic brain injury. The tool helps prepare families for their role as decision-makers an…

This study tested whether a mobile app-based speech therapy program is practical for stroke survivors with mild to moderate communication problems. Twenty patients discharged from the hospital used an iPad for therapy at home while waiting for outpatient services. The main goal w…

This study looked at what makes it easier or harder for veteran stroke survivors to do arm and hand exercises at home. Researchers gave surveys about mood, confidence, and sleep, then used a wearable tracker to measure exercise. The goal is to find ways to help people stick with …

This study looked at whether adding a brain MRI and a check by a nerve specialist could help doctors make better treatment decisions for people with a serious heart infection called infectious endocarditis. The infection can cause silent strokes, and the goal was to see if findin…

This study tested whether community education and hospital improvements could increase the use of clot-busting drugs for stroke in Flint, Michigan. Researchers enrolled nearly 6,000 adult stroke patients across three hospitals. The community intervention included workshops, a mus…

This study used wearable accelerometers to measure how much and how intensely 15 stroke survivors moved their affected arm during everyday activities and therapy. The goal was to see if arm use improved over time. No treatment was tested; the study only observed and recorded move…

This study looked at how to improve care for dizzy patients in the emergency department. Over 90,000 adults participated. The goal was to help doctors use proven tests and treatments for common causes of dizziness like BPPV. The study tested new training and tools to make sure pa…

This completed study used ultrasound to look at the shape and structure of spastic muscles in the arms and legs of 80 stroke survivors. The goal was to see if ultrasound can help doctors better understand and measure muscle changes after stroke. The findings may improve how spast…

This study looked at how blood moves through leg muscles in people who have had a stroke compared to healthy adults. Researchers used gentle leg movements and muscle contractions to measure blood flow. The goal was to learn more about why stroke survivors often have reduced exerc…

This study adapted several questionnaires that measure arm and hand function after a stroke into Polish, and checked how reliable and accurate they are. One hundred people who had an ischemic stroke at least six months ago took part. The goal was to give Polish-speaking patients …

This early-stage study tested the safety and tolerability of a new drug called HRS-8829 in 83 healthy adults aged 18 to 55. The drug is being developed for acute ischemic stroke. Participants received either the drug or a placebo, and researchers monitored side effects and how th…

This study tested a program where doctors refer inactive people with chronic diseases (like diabetes, heart disease, or obesity) to an exercise professional for personalized counseling. The goal was to see if this referral scheme helps people become more active compared to just g…

This study tested a new ultrasound technique called ultrasound localization microscopy (ULM) to see very small arteries in the brain. Researchers used it on 24 people who had a stroke or Moya Moya disease. The goal was to see if ULM could find more tiny arteries than standard MRI…

This completed study followed 282 first-time stroke patients for six months to see how well they stuck with their rehabilitation exercises. Researchers used a special model to identify different patterns of compliance and what factors—like physical, mental, or social—might predic…

This study looked at how the brains of people with aphasia (a language disorder after stroke) and healthy people work together during gestures. Using EEG, researchers measured brain synchronization while participants watched and copied different types of gestures. The goal was to…

This study looked at 332 stroke patients to see if general anesthesia or conscious sedation is better during a procedure to remove blood clots from the brain. The goal was to find which method leads to better recovery and fewer complications within the first week. The results cou…

This completed study looked at how brain lesions from strokes impact cognitive control—the ability to focus, switch tasks, and make decisions. Researchers tested 184 healthy adults and stroke patients using behavioral tasks, brain scans (MRI), and EEG. The goal was to understand …

This study looked at whether virtual reality can help stroke survivors who have an uneven walk (one leg takes longer steps than the other). 42 adults who had a stroke at least 3 months ago took part. They learned a new walking task in virtual reality, and researchers measured how…

This study followed 82 people with blocked arteries supplying the back of the brain to see if low blood flow raises the risk of stroke or mini-stroke. Participants had already experienced a stroke or transient ischemic attack (TIA) and had at least 50% blockage in those arteries.…

This study checked whether the Turkish version of the Cardiac Depression Scale (CDS) works well for people with heart disease. Researchers tested 360 Turkish adults with various heart conditions to see if the scale accurately measures depression. The goal is to give doctors a rel…

This study tested whether wrist-worn accelerometers can accurately measure how much stroke patients use their weaker arm during everyday activities like dressing and eating. Twenty-five participants were recorded with both accelerometers and video cameras. The goal was to see if …

This completed study looked at 400 people with both heart disease and a mental health condition (like depression or anxiety). Researchers used questionnaires, blood tests, and imaging to find shared risk factors and biological markers. The goal was to better understand how these …

This study looked at 55 stroke survivors to see if reducing sitting time early after stroke helps with walking and daily function. Researchers also checked if brain scan markers can predict who benefits most from rehab. The goal is to create personalized recovery plans based on e…

This study looked at 481 stroke patients who had a procedure to remove a blood clot from their brain. Researchers compared those who received general anesthesia (fully asleep) versus sedation (awake but relaxed). They tracked death rates and recovery to see if one method was bett…

This study tested whether a 1-minute 51-second animated video called FAST BEE helps people learn and remember stroke warning signs. Over 300 healthy adults and teens watched the video and then answered questions about what they learned. The goal was to see if the video improves r…

This study looked at 455 stroke patients to see if a continuous finger blood pressure monitor (Clearsight) or standard arm cuff measurements better predict brain bleeding after clot removal. Each patient had both methods used within 24 hours after treatment. The goal was to see w…

This early study tested whether breathing short bursts of low oxygen (like being on a tall mountain) is safe for people who had a stroke. The idea is that this might trigger the brain to release proteins that help it recover. 16 stroke survivors took part, and the main goal was t…

This study looked at 79 people who had a stroke to see if levels of a protein called PrPC in their blood were linked to how severe the stroke was and how well they recovered. Researchers collected blood samples and checked patients' health 3 months later. No treatments were teste…

This study looked at 70 people who had a brain hemorrhage (bleeding stroke) to see if a special PET scan could tell whether the bleeding was caused by amyloid buildup in blood vessels or by high blood pressure. Participants received an injection of a radioactive tracer called Flo…

This early-phase trial tested the safety of a new drug called BB-025, designed to reverse the effects of another experimental drug, BB-031. 72 healthy volunteers received either BB-025 or a placebo, alone or after BB-031, and were monitored for 28 days. The main goal was to check…

This study checked how well the Fugl-Meyer Assessment (a test for stroke recovery) works in people recovering from a stroke. Over 100 patients in rehab were tested when they arrived and when they left. The goal was to see if the test accurately tracks improvement.

This study tested whether a quick ankle manipulation (a high-velocity, low-amplitude traction) can change muscle structure in people who had a stroke at least six months ago. 36 participants received both the real manipulation and a placebo in random order. Researchers used ultra…

This study measured muscle loss (sarcopenia) in 80 stroke survivors using simple tests like grip strength, walking speed, and ultrasound. Researchers compared patients who had a stroke recently (post-acute care) with those who had one over a year ago. The goal was to see how age,…

This study looked at 150 stroke patients in a rehab hospital to see if changes in their ability to do daily activities, walk, balance, think, and use their hands were linked to whether they went home or to another facility after discharge. Researchers used existing medical record…

This completed study looked at 44 stroke patients to see how their bone density differs between the paralyzed and non-paralyzed leg. Researchers measured bone density in the hip and spine using a special X-ray scan. The goal was to better understand which clinical factors are lin…

This study looked at 53 stroke survivors to see if fatigue severity is linked to their quality of life. Participants filled out two questionnaires: one about fatigue and one about health-related quality of life. The goal was to understand how much fatigue independently affects we…

This study tested whether wearing a carbon fiber ankle foot orthosis (AFO) helps stroke survivors walk better while doing another task, like listening or carrying something. Twenty-six stroke survivors walked with and without the brace while researchers measured their walking spe…

This study looked at 29 children with brain injuries to test two new methods for checking how well the brain controls its own blood flow. The goal was to see if these methods could help doctors better understand and treat brain injuries. The study did not test a treatment, but ai…

This completed study looked at how leg muscles work during walking in 500 people who had a stroke. The goal was to understand muscle patterns, test how well current measurement methods work, and find early signs that predict walking recovery. The results could help doctors create…

This study looked at 160 adults having planned brain surgery to see if raising blood pressure during the operation makes it harder for surgeons to stop bleeding. Doctors increased blood pressure slightly with a medicine and noted if extra steps were needed to control bleeding. Th…

This completed study looked at how a person's total daily-life exposure—called the 'exposome'—affects health after a stroke. Researchers tracked 150 stroke survivors, measuring biological, environmental, social, and lifestyle factors alongside motor and cognitive tests. The goal …

This study tested a new MRI method to better predict stroke risk in people with intracranial atherosclerosis, a condition where arteries in the brain become narrowed. Researchers measured how well different parts of the brain responded to changes in blood flow. The goal was to fi…

This study looked at how doing a thinking task while walking affects the brain in people who have had a stroke. Eleven stroke survivors walked on a special mat while a brain scanner measured their brain activity. The goal was to understand why walking gets harder when you have to…

This study tested whether a special type of MRI, called high-resolution vessel wall imaging, can help predict if a stroke will happen again in people with a narrowed brain artery. Researchers followed 74 patients who had a stroke or mini-stroke and received artery-opening treatme…

This study looked at how many times people should perform the Nine Hole Peg Test—a simple hand coordination test—to get reliable results after a stroke. Researchers tested 40 healthy adults and stroke survivors aged 20-64. The goal is to improve how doctors measure motor recovery…

This study tested a program to help people with stroke or TIA transition from hospital to home. 213 participants received either the program or usual care. The program focused on improving communication, health literacy, and medication management. Researchers measured quality of …

This study worked with 49 stroke patients, their families, and healthcare teams to design and test a more personalized way to move from the hospital to home rehabilitation. The goal was to improve the quality of care transitions and health literacy. The study did not test a treat…

This study tested whether home automation and remote monitoring can help elderly people (65+) with multiple chronic conditions live safely at home. Over 500 participants had their homes equipped with sensors that tracked health signs and sent alerts to doctors. The main goal was …

This study tested whether a special MRI scan called IVIM can predict how well people recover three months after an acute ischemic stroke. Researchers added a two-minute scan to the standard MRI for 274 adults admitted with stroke. They then compared the scan results to the patien…

This study looked at 174 adults who had a stroke and were treated under general anesthesia. Researchers compared removing the breathing tube early versus later to see which approach leads to better functional recovery after 90 days. The goal is to find the best time to take patie…

This study examined 200 adults who had surgery to remove plaque from their carotid arteries. Researchers identified bacteria living inside the plaques and tracked whether certain types were linked to later strokes, re-narrowing of the artery, or death. The goal was to learn which…

This study tested whether raising the legs (elevated leg positioning) is safe and practical for people who have had a moderate ischemic stroke. Fifty adults with moderate stroke symptoms were enrolled within 24 hours of symptom onset. The goal was to see if this simple, non-drug …

This completed study looked at 26,000 patients who had outpatient procedures for blood vessel problems like peripheral artery disease, varicose veins, or dialysis access issues. The goal was to see how safe and effective these procedures are when done in an office-based angiosuit…

This study observed how breathing machines (mechanical ventilation) are used in 2,299 brain-injured patients in intensive care units worldwide. Researchers collected data on different ventilation strategies and their link to patient recovery. No new treatments were tested; the go…

This study looked at whether wearing an activity monitor (like a Fitbit) after heart surgery helps patients get moving sooner and return to their normal activity levels faster. Researchers tracked motivation, length of hospital stay, and readmission rates in 12 adults who had car…

This small study tested whether applying magnetic pulses to the brain's sensory area could help stroke survivors learn movements better. Twenty people who had a stroke at least three months ago received the stimulation while researchers measured brain activity and motor responses…

This study collected data from over 1,100 stroke patients to build a computer model, or 'digital twin,' that predicts how well someone will recover. By analyzing movement patterns and medical records with artificial intelligence, researchers aim to forecast long-term disability. …

This study looked at 70 family caregivers of stroke patients who also have bladder issues. Researchers measured how much burden, fatigue, poor sleep, and depression caregivers experience. The goal was to understand the challenges these caregivers face, not to test a new treatment…

This study tested whether a simple paper-based balance test is reliable and valid for people who have had a stroke. Researchers measured balance, ankle strength, and fall risk in 44 stroke survivors. The goal was to see if the paper test could be a useful tool for doctors and the…

This completed study tested whether mild electrical stimulation of the outer ear (taVNS) can change how brain regions communicate in people who had a stroke more than 6 months ago, as well as in healthy adults. Researchers used a brain-imaging technique called fNIRS to measure re…

This study looked at 50 people who had a mild stroke to understand why they might struggle with everyday activities like work, hobbies, or socializing. Researchers wanted to see if factors like mood, fatigue, or thinking problems make these gaps worse, and if having more gaps low…

This study looked at 100 people who recently had a major heart attack to better understand blood clots that can form in the heart's main pumping chamber. Using special PET/MR scans, researchers tracked clot activity in the heart and brain over several months. The goal was to lear…

This study tested whether telephone interviews after a stroke can help patients better understand and follow their medication plans. 54 adults who had an ischemic stroke and were returning home received a pharmaceutical interview before discharge, followed by phone calls at one w…

This study looked at brain activity in 64 people (some who had a stroke and some healthy) while they moved their arms with different levels of effort. The goal was to understand how the brain responds during rehabilitation exercises. Researchers used a special brain scanner (fNIR…

This study measured levels of a brain protein called BDNF in 50 stroke patients who received a clot-busting drug. Researchers wanted to see if BDNF levels rise after treatment and if they could help predict recovery of movement, thinking, and mood three months later. The goal is …

This study looked at how walking speed changes the way stroke survivors walk. Fifteen people who had a stroke and could walk with or without help were asked to walk at different speeds while their steps were measured. The goal was to understand how speed affects step length, bala…

This study looked at 1499 people who had an acute ischemic stroke and got a chest CT within 24 hours. Researchers wanted to see if combining CT findings with clinical signs and inflammation markers could better predict who would develop pneumonia within a week. They built and tes…

This study looked at how the calf muscle and Achilles tendon work together during walking in people who have had a stroke or spinal cord injury, compared to healthy individuals. Researchers used ultrasound and motion analysis to measure muscle and tendon lengths in 64 adults. The…

This small pilot study explored whether advanced heart imaging can detect hidden strokes in people who have never had atrial fibrillation but are at high risk due to conditions like diabetes or heart failure. Researchers used brain MRIs to find silent, symptom-free strokes and li…

This study followed 167 people with atrial fibrillation or flutter who had a catheter ablation procedure. Researchers measured changes in stroke and bleeding risk scores before and 3, 6, and 12 months after ablation. They also compared different monitoring methods, including impl…

This study tested whether special communication training for pharmacists and general practitioners helps them involve older patients in decisions to stop or lower medications for heart disease and diabetes. Researchers enrolled 310 patients aged 75 and older who were taking certa…

This Phase 1 trial tested the safety of LT3001, a potential clot-busting drug for acute ischemic stroke, in 65 healthy adults. Participants received multiple doses of LT3001 alone or with common stroke medications like aspirin and clopidogrel. The goal was to check for side effec…

This study tested whether intensive treadmill training with a harness to support body weight can improve walking and balance in people who recently had a stroke. Forty participants in the subacute phase (2-6 weeks after stroke) completed a 3-week program. Researchers also measure…

This first-in-human study tested a new smart guidewire (Clotild®) in 45 stroke patients undergoing emergency clot removal. The wire helps guide the removal tool and also measures the clot's electrical properties to determine its composition. The main goal was to check safety, suc…

This study checked if a Turkish version of the Bolus Residue Scale (BRS) is a reliable way to measure swallowing problems in people who recently had a stroke. Researchers looked at video recordings of 40 patients swallowing and had experts rate the results. The goal was to make s…

This study looked at over 2,400 stroke patients who received clot-busting drugs (alteplase or tenecteplase) within 4.5 hours of symptoms. Researchers wanted to see if adding Shuxuetong injection, a traditional Chinese medicine, could improve recovery and reduce disability. The go…

This small pilot study looked at whether aerobic exercise can improve memory, attention, and fatigue in people who had a stroke or traumatic brain injury. Twelve participants were split into two groups: one did 30 minutes of aerobic exercise 3-4 times a week for 8 weeks, while th…

This study tested whether a theory-based motivational letter mailed six months in advance could increase attendance at a one-year post-cardiac rehabilitation check-up. Researchers compared 102 adults who received the letter to those who got usual care. The goal was to see if a si…

This study looked at how small blood vessels in the brain change after a stroke caused by small vessel disease. Researchers used a special 3D X-ray technique to take detailed pictures of these vessels. The goal was to learn more about the disease process, which could help doctors…

This completed study involved over 36,000 patients and aimed to create quality indicators for stroke and chronic coronary syndrome care using French national health databases. Researchers linked patient data from practice registries to the national database to validate these indi…

This study looked at 91 Chinese patients with atrial fibrillation who had a stroke while taking blood thinners (NOACs). The goal was to understand why these strokes happen and whether not taking the medication as prescribed played a role. Researchers hope this knowledge will help…

This study tested a virtual reality (VR) system to measure how quickly stroke survivors react to objects on their left or right side. Researchers compared these VR results with standard paper tests for spatial neglect. The goal was to see if VR can reliably assess attention probl…

This study evaluated how aware caregivers are of secondary complications after a stroke, such as muscle stiffness, swallowing problems, and depression. Researchers surveyed 80 caregivers of stroke patients to see if education during rehabilitation improves their knowledge. The go…

This study looked at 120 people who had an acute ischemic stroke to see if the types of bacteria in their gut were linked to how well they recovered. Researchers analyzed stool samples and brain scans, and tracked disability over 6 months. The goal was to understand the role of g…

This study measured the amount of common blood thinners (dabigatran, apixaban, and rivaroxaban) in the blood of 308 Chinese adults with atrial fibrillation who had been taking the medication for at least 3 months. The goal was to establish normal reference ranges for these drugs …

This study looked at why people who had a stroke stop getting botulinum toxin (Botox) injections for muscle stiffness. Researchers reviewed records of 81 patients over 12 years and found that most received only one injection. The main reason for stopping was that patients were no…

This study looked at how stroke survivors respond to robot-assisted therapy compared to traditional occupational therapy. Thirty people who had a stroke within the past three months tried both types of therapy in single sessions. Researchers measured how many arm movements they m…

This completed study looked at 213 people with acute ischemic stroke to see if combining brain scans with blood tests could better predict complications like brain swelling or bleeding. Researchers also used a mouse model to study how brain cells change after stroke. The goal is …

This study tested a French version of a questionnaire that measures physical activity levels in people with physical disabilities. Fifty participants with conditions like stroke, multiple sclerosis, or Parkinson's disease filled out the questionnaire twice, two weeks apart. The g…

This study looked at how clenching your jaw or having an uneven bite affects balance and the risk of falling in people who have had a stroke. Sixty stroke survivors completed balance tests on special platforms while researchers measured their stability. The goal was to understand…

This study looked at whether a hand-held device called a dynamometer can accurately measure leg strength in 20 people who had a stroke more than 3 months ago. The goal was to reduce measurement errors and give therapists better information for designing therapy. Participants perf…

This study looked at 208 adults with severe brain injuries from bleeding or trauma. Researchers used a special monitor to track brain temperature and pressure together. The goal was to see if certain patterns could predict how well patients would recover 30 days later.

This study looked at whether doing virtual reality exercises with other people (multi-player) is more motivating than doing them alone. It included 86 participants: healthy teens, children with motor disorders, and older adults with conditions like stroke or COPD. Researchers mea…

This study tested two heart monitoring methods in 516 people who had a transient ischemic attack (TIA or mini-stroke). The goal was to see which method better detects hidden atrial fibrillation, a heart rhythm problem that raises stroke risk. Participants received either a small …

This study looked at 126 people who recently had a stroke caused by a blocked blood vessel in the brain. Researchers wanted to find out how common fatigue is after a stroke and what factors might be linked to it, including any treatments given in the first days. Participants comp…

This study followed 188 children who had seizures shortly after birth to see how they develop over time. Researchers measured thinking skills, behavior, and daily function. The goal is to understand which children are at higher risk for conditions like cerebral palsy or intellect…

This study looked at how adding tilt-table exercise or motor imagery (mentally practicing movement) to standard therapy affects walking and trunk stability in stroke patients. Sixty-six people who had a stroke 6-8 weeks earlier took part. The goal was to measure changes in gait a…

This study looked at whether doctors, nurses, or standard risk scores are better at predicting long-term recovery after a brain hemorrhage. Over 1,000 patients were followed for 6 months. The goal is to improve how we estimate outcomes for these serious conditions.

This study used artificial intelligence to learn the patterns of reduced blood flow to the brain during planned surgeries. 60 patients having carotid artery surgery or stroke clot removal were monitored with non-invasive devices. The goal was to teach AI to recognize these patter…

This study looked at whether online training can improve how well emergency department doctors interpret CT head scans. 173 clinicians from 6 UK hospitals took part. One group received training early, while a control group got it later. The goal was to see if training boosts accu…

This study aimed to better understand why some people develop delayed brain damage after a brain aneurysm rupture. Researchers measured platelet activation over time in 90 patients, comparing those with aneurysm bleeds to those with other types of brain bleeds. The goal was to cl…

This completed study tested a program to help stroke survivors in rural Kentucky take their blood pressure medications as prescribed. Four participants received one-on-one education and tailored sessions from a pharmacy technician and community health worker. The goal was to see …