Can sound waves reawaken the brain after stroke?

NCT ID NCT05016531

Completed Disease control Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This trial tests whether low-intensity focused ultrasound (LIFU) can safely stimulate the brain to help people recover arm and hand function after a stroke. Researchers will try different intensities and frequencies of ultrasound in stroke survivors to find the best settings that are both safe and tolerable. The goal is to see if this non-invasive technique can improve brain excitability and potentially aid rehabilitation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Low-intensity focused ultrasound (LIFU) brain stimulation
What this could lead to: If successful, this could identify a safe, non-invasive way to boost brain activity and improve arm and hand movement in stroke survivors.
What could go wrong: This is an early, small study focused on safety and tolerability. It may not show clear benefit, and there are risks like scalp burns, seizures, or new brain lesions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEMORRHAGIC STROKE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

hemorrhagic stroke ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STROKE

Contacts and locations

Locations

Duke University Hospital

Durham, North Carolina, 27710, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.