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Could inflammation after stroke trigger depression?

NCT ID NCT02368145

Completed Knowledge-focused Sponsor: Alexander Kusnecov, Ph.D. Source: ClinicalTrials.gov ↗

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study investigates whether inflammation and stress compounds in the blood are linked to depression after a stroke. Researchers measure inflammatory markers and stress hormones in blood samples from 25 adults who have had an acute ischemic stroke. Participants also complete depression and anxiety questionnaires at several time points over 90 days. The goal is to better understand the biological connection between stroke-related brain injury and mood changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If links are found, it could point toward new ways to predict or treat depression after a stroke.
What could go wrong
This is a small observational study with only 25 people, so results may not apply to everyone. It looks for patterns, not a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE STROKE STROKE

Contacts and locations

Locations

  • Rutgers, The State University

    New Brunswick, New Jersey, 08901, United States

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