Brain scans reveal how language therapy rewires Stroke-Damaged brains

NCT ID NCT01927302

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This study investigates how different language treatments affect both language skills and brain function in people with aphasia, a condition that impairs the ability to speak, understand, read, or write after a stroke. Participants will receive therapy targeting naming, spelling, or sentence processing, and will undergo brain scans before and after treatment to track changes. The goal is to understand which therapies produce the best language recovery and how the brain adapts.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

language treatment (naming, spelling, or sentence processing therapy)

What this could lead to

If successful, this could reveal which language therapies best rewire the brain after stroke, guiding more effective rehabilitation.

What could go wrong

This is an early-stage observational study with only 90 participants, so results may not apply to all people with aphasia. The therapies may not produce lasting improvements.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agraphia aphasia Aphasia, Broca dysgraphia nominal aphasia progressive non-fluent aphasia stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston University

    Boston, Massachusetts, 02215, United States

  • Harvard University

    Cambridge, Massachusetts, 02138, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21218, United States

  • Northwestern University

    Chicago, Illinois, 60208, United States