New aspiration tubing aims to restore blood flow faster in major strokes

NCT ID NCT05437055

Completed Disease control Sponsor: Penumbra Inc. Source: ClinicalTrials.gov ↗

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests a device called the Penumbra System with Thunderbolt Aspiration Tubing to remove blood clots in people having a severe stroke caused by a blockage in a large brain artery. The goal is to see if the device can safely and effectively restore blood flow within 8 hours of symptoms starting. Participants are adults aged 18 to 80 who are eligible for mechanical thrombectomy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Penumbra System with Thunderbolt Aspiration Tubing (mechanical thrombectomy device)
What this could lead to: If successful, this device could improve blood flow restoration in stroke patients, potentially reducing brain damage and disability.
What could go wrong: This is a device study without a control group, so benefits may not be proven. Risks include vessel damage, bleeding, or failure to remove the clot.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cerebral artery occlusion ischemic stroke large artery stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIC STROKE LARGE VESSEL OCCLUSION

Contacts and locations

Locations

Abbott Northwestern

Minneapolis, Minnesota, 55427, United States
Abrazo West Campus

Goodyear, Arizona, 85395, United States
Albany Medical Center

Albany, New York, 12208, United States
Christiana Care

Newark, Delaware, 19718, United States
Christus Trinity Medical Center

Tyler, Texas, 75702, United States
Edward Elmhurst Health

Naperville, Illinois, 60540, United States
Fort Sanders

Knoxville, Tennessee, 37916, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
HRI - Swedish

Englewood, Colorado, 80113, United States
Indiana U. Health

Indianapolis, Indiana, 46202, United States
Jackson Memorial (U. of Miami)

Miami, Florida, 33136, United States
KUMC

Kansas City, Kansas, 66160, United States
MUSC

Charleston, South Carolina, 29425, United States
Massachusetts General

Boston, Massachusetts, 02114, United States
Methodist U.

Memphis, Tennessee, 38104, United States
Nebraska Medical

Omaha, Nebraska, 68198, United States
New Hanover Regional

Wilmington, North Carolina, 28401, United States
North Shore U.

Evanston, Illinois, 60201, United States
Piedmont Hospital Atlanta

Atlanta, Georgia, 30309, United States
Riverside Regional Medical Center

Newport News, Virginia, 23601, United States
Sharp Grossmont

San Diego, California, 92123, United States
St. Dominic

Jackson, Mississippi, 39216, United States
St. Joseph - BayCare

Tampa, Florida, 33614, United States
Stonybrook U.

Stony Brook, New York, 11794, United States
Thomas Jefferson University

Philadelphia, Pennsylvania, 19107, United States
UMass Memorial Medical Center

Worcester, Massachusetts, 01655, United States
UT Houston

Houston, Texas, 77030, United States
University of Buffalo

Buffalo, New York, 14203, United States
Valley Medical Center

Renton, Washington, 98055, United States
Wellspan York

York, Pennsylvania, 17403, United States
Wellstar Kennestone Hospital

Marietta, Georgia, 30060, United States
Yale New Haven

New Haven, Connecticut, 06520, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.