Sugar-Based gel shows promise for stroke patients in early trial

NCT ID NCT06700824

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tested a new gel called OTR4132 in 60 people who had a stroke and received a clot-removal procedure. The gel is designed to help repair damaged brain tissue. Researchers measured neurological function at 24 hours and disability at 3 months to see if the gel improves recovery compared to a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

OTR4132 (a sugar-based gel that helps repair damaged tissue)

What this could lead to

If it works, this could point toward a new treatment to help people recover better after a stroke.

What could go wrong

This is a small, early-phase trial with only 60 people, so results may not apply to everyone. The treatment is still experimental and may not show clear benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cerebral infarction ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Locations

  • CHU Henri-Mondor

    Créteil, 94000, France

  • Centre Hospitalier Régional Universitaire de Lille- Hôpital Roger Salengro

    Lille, 59000, France

  • Centre Hospitalier Régional Universitaire de Nancy

    Nancy, 54000, France

  • Centre Hospitalier Universi-taire de Bordeaux-Hôpital Pellegrin

    Bordeaux, 33076, France

  • Centre Hospitalier Universitaire Grenoble Alpes

    Grenoble, 38043, France

  • Centre Hospitalier Universitaire de Martinique

    Fort de France, 97261, France

  • Centre Hospitalier Universitaire de la Guadeloupe

    Pointe à Pitre, 97159, France

  • Centre hospitalier universi-taire de Brest (Cavale Blanche)

    Brest, 29609, France

  • GHU Paris Psychiatrie & Neurosciences

    Paris, France, France

  • Hôpital Foch

    Suresnes, 92150, France

  • Hôpital Fondation Adolphe de Rothschild Service de neuro-vasculaire

    Paris, 75019, France

  • Hôpital de Hautepierre

    Strasbourg, 67200, France

  • Hôpital de la Pitié Salpêtrière - AP-HP

    Paris, 75013, France

  • Hôpitaux Universitaires De Marseille Timone-AP-HM

    Marseille, 13385, France

  • UIC Imagerie et Neurovasculaire CHU de Nantes

    Nantes, 44093, France