Sugar-Based gel shows promise for stroke patients in early trial

NCT ID NCT06700824

Completed Disease control Sponsor: Organ, Tissue, Regeneration, Repair and Replacement Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tested a new gel called OTR4132 in 60 people who had a stroke and received a clot-removal procedure. The gel is designed to help repair damaged brain tissue. Researchers measured neurological function at 24 hours and disability at 3 months to see if the gel improves recovery compared to a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: OTR4132 (a sugar-based gel that helps repair damaged tissue)
What this could lead to: If it works, this could point toward a new treatment to help people recover better after a stroke.
What could go wrong: This is a small, early-phase trial with only 60 people, so results may not apply to everyone. The treatment is still experimental and may not show clear benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cerebral infarction ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOVASCULAR THROMBECTOMY ISCHEMIC CEREBROVASCULAR ACCIDENT

Contacts and locations

Locations

CHU Henri-Mondor

Créteil, 94000, France
Centre Hospitalier Régional Universitaire de Lille- Hôpital Roger Salengro

Lille, 59000, France
Centre Hospitalier Régional Universitaire de Nancy

Nancy, 54000, France
Centre Hospitalier Universi-taire de Bordeaux-Hôpital Pellegrin

Bordeaux, 33076, France
Centre Hospitalier Universitaire Grenoble Alpes

Grenoble, 38043, France
Centre Hospitalier Universitaire de Martinique

Fort de France, 97261, France
Centre Hospitalier Universitaire de la Guadeloupe

Pointe à Pitre, 97159, France
Centre hospitalier universi-taire de Brest (Cavale Blanche)

Brest, 29609, France
GHU Paris Psychiatrie & Neurosciences

Paris, France, France
Hôpital Foch

Suresnes, 92150, France
Hôpital Fondation Adolphe de Rothschild Service de neuro-vasculaire

Paris, 75019, France
Hôpital de Hautepierre

Strasbourg, 67200, France
Hôpital de la Pitié Salpêtrière - AP-HP

Paris, 75013, France
Hôpitaux Universitaires De Marseille Timone-AP-HM

Marseille, 13385, France
UIC Imagerie et Neurovasculaire CHU de Nantes

Nantes, 44093, France

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