Can numbing cream boost recovery after spinal injury?
NCT ID NCT05589402
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tests a simple idea: temporarily numbing non-paralyzed arm muscles with an over-the-counter lidocaine cream while exercising paralyzed muscles. Researchers hope this will improve strength, function, and sensation in people with spinal cord injury. About 30 adults with chronic incomplete spinal cord injury will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lidocaine cream 5% (numbing cream) plus rehabilitation movement training
What this could lead to
If it works, this could point toward a simple, low-cost way to make rehab more effective for people with spinal cord injury.
What could go wrong
This is a very early Phase 1 trial with only 30 participants, so results may not be conclusive. The numbing cream is temporary and may not produce lasting improvements.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Texas Rio Grande Valley
Harlingen, Texas, 78550, United States