Can numbing cream boost recovery after spinal injury?

NCT ID NCT05589402

Completed Symptom relief Sponsor: University of Texas Rio Grande Valley Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This early study tests a simple idea: temporarily numbing non-paralyzed arm muscles with an over-the-counter lidocaine cream while exercising paralyzed muscles. Researchers hope this will improve strength, function, and sensation in people with spinal cord injury. About 30 adults with chronic incomplete spinal cord injury will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Lidocaine cream 5% (numbing cream) plus rehabilitation movement training
What this could lead to: If it works, this could point toward a simple, low-cost way to make rehab more effective for people with spinal cord injury.
What could go wrong: This is a very early Phase 1 trial with only 30 participants, so results may not be conclusive. The numbing cream is temporary and may not produce lasting improvements.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

spinal cord injury stroke disorder vertebral column disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SPINAL CORD INJURIES SPINE DISEASE STROKE

Contacts and locations

Locations

University of Texas Rio Grande Valley

Harlingen, Texas, 78550, United States

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