Could an arthritis drug help the brain heal after a stroke?

NCT ID NCT06737705

Completed Disease control Sponsor: De-zhi Kang Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether baricitinib, an anti-inflammatory drug, can improve neurological outcomes in people who have had a spontaneous intracerebral hemorrhage (a type of stroke caused by bleeding in the brain). About 110 adults in China will receive either baricitinib plus standard care or standard care alone for 14 days. The study measures recovery using the modified Rankin Scale, which assesses disability after stroke.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: baricitinib
What this could lead to: If it works, this could point toward a new treatment to improve recovery after a brain bleed.
What could go wrong: This is an early phase 2 trial with only 110 participants, so results may not apply to everyone. Baricitinib can suppress the immune system, raising infection risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intracerebral hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRACEREBRAL HEMORRHAGE

Contacts and locations

Locations

First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, 350003, China
First Affiliated Hospital of Gannan Medical University

Ganzhou, Jiangxi, 341000, China
Ganzhou People's Hospital

Ganzhou, Jiangxi, 341000, China
Liaocheng People's Hospital, Liaocheng Brain Hospital

Liaocheng, Shandong, China
The Southwest Hospital of Army Medical University

Chongqing, Chongqing Municipality, 400038, China
Tianjin Huanhu Hospital

Tianjin, Tianjin Municipality, China

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