Could an arthritis drug help the brain heal after a stroke?

NCT ID NCT06737705

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether baricitinib, an anti-inflammatory drug, can improve neurological outcomes in people who have had a spontaneous intracerebral hemorrhage (a type of stroke caused by bleeding in the brain). About 110 adults in China will receive either baricitinib plus standard care or standard care alone for 14 days. The study measures recovery using the modified Rankin Scale, which assesses disability after stroke.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

baricitinib

What this could lead to

If it works, this could point toward a new treatment to improve recovery after a brain bleed.

What could go wrong

This is an early phase 2 trial with only 110 participants, so results may not apply to everyone. Baricitinib can suppress the immune system, raising infection risk.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

intracerebral hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • First Affiliated Hospital of Fujian Medical University

    Fuzhou, Fujian, 350003, China

  • First Affiliated Hospital of Gannan Medical University

    Ganzhou, Jiangxi, 341000, China

  • Ganzhou People's Hospital

    Ganzhou, Jiangxi, 341000, China

  • Liaocheng People's Hospital, Liaocheng Brain Hospital

    Liaocheng, Shandong, China

  • The Southwest Hospital of Army Medical University

    Chongqing, Chongqing Municipality, 400038, China

  • Tianjin Huanhu Hospital

    Tianjin, Tianjin Municipality, China