Balloon trick after clot removal may shield the brain

NCT ID NCT06545734

First seen Jun 22, 2026

Summary

This study tested whether a special balloon procedure, called direct ischemic post-conditioning, can reduce brain injury in people who just had a stroke from a large blocked artery. Sixty patients were randomly assigned to get either standard clot removal alone or clot removal plus the balloon procedure, which briefly stops and restarts blood flow. The goal is to see if this technique limits brain damage and improves recovery.

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Contacts and locations

Locations

  • Tianjin Huanhu Hospital

    Tianjin, Tianjin Municipality, 300070, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Direct ischemic post-conditioning (a procedure using a balloon to briefly block and restore blood flow after clot removal)

What this could lead to

If it works, this could point toward a simple, low-cost way to limit brain damage after a stroke and improve recovery.

What could go wrong

This is a small, early pilot study with only 60 participants. The procedure may not provide benefit, and there is a risk of vessel injury or bleeding from the balloon inflation.

Conditions

The condition(s) this trial relates to.

large artery stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.