Heart valve procedure: new drug may shield brain and kidneys
NCT ID NCT05145283
First seen Apr 24, 2026 · Last updated Apr 25, 2026 · Updated 1 time
Summary
This study tested a drug called conestat alfa in 141 people getting a new heart valve (TAVI) for severe aortic stenosis. The goal was to see if it could prevent small strokes and kidney damage that sometimes happen after the procedure. Participants received either the drug or a placebo before their valve replacement, and brain scans were used to check for injury.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Stadtspital Triemli Zürich, Division of Cardiology
Zurich, 8063, Switzerland
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University Hospital Basel, Division of Internal Medicine
Basel, 4031, Switzerland
Conditions
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