New stroke clot removal technique could boost recovery rates

NCT ID NCT02523261

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways to remove large blood clots from the brain during a stroke: direct aspiration (ADAPT) and using a stent retriever. About 381 adults with stroke caused by a blocked artery in the front part of the brain took part. The goal is to see which method clears the blockage more completely and safely, potentially improving patients' recovery and reducing long-term disability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

direct aspiration procedure (ADAPT) and stent retriever procedure

What this could lead to

If ADAPT proves superior, it could become the preferred first-line technique for removing large clots in stroke patients, leading to better recovery and less disability.

What could go wrong

This is a completed study, but results may not apply to all stroke types or settings. The techniques are invasive and carry risks like vessel damage or bleeding.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cerebral infarction ischemic stroke large artery stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Dupuytren

    Limoges, France

  • CHU Hôpital Gui de Chaulac

    Montpellier, France

  • CHU Pellegrin

    Bordeaux, France

  • Fondation Ophtalmologique Adolphe de Rothschild

    Paris, 75019, France

  • Hospices Civils de Lyon

    Bron, France

  • Hôpital Foch

    Suresnes, France

  • Hôpital Guillaume et René LAENNEC

    Nantes, France

  • Hôpital Neurologique

    Nancy, France