New stroke clot removal technique could boost recovery rates

NCT ID NCT02523261

Completed Disease control Sponsor: Fondation Ophtalmologique Adolphe de Rothschild Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways to remove large blood clots from the brain during a stroke: direct aspiration (ADAPT) and using a stent retriever. About 381 adults with stroke caused by a blocked artery in the front part of the brain took part. The goal is to see which method clears the blockage more completely and safely, potentially improving patients' recovery and reducing long-term disability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: direct aspiration procedure (ADAPT) and stent retriever procedure
What this could lead to: If ADAPT proves superior, it could become the preferred first-line technique for removing large clots in stroke patients, leading to better recovery and less disability.
What could go wrong: This is a completed study, but results may not apply to all stroke types or settings. The techniques are invasive and carry risks like vessel damage or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cerebral infarction ischemic stroke large artery stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIC CEREBROVASCULAR ACCIDENT

Contacts and locations

Locations

CHU Dupuytren

Limoges, France
CHU Hôpital Gui de Chaulac

Montpellier, France
CHU Pellegrin

Bordeaux, France
Fondation Ophtalmologique Adolphe de Rothschild

Paris, 75019, France
Hospices Civils de Lyon

Bron, France
Hôpital Foch

Suresnes, France
Hôpital Guillaume et René LAENNEC

Nantes, France
Hôpital Neurologique

Nancy, France

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