Could a common antidote help stroke patients?
NCT ID NCT04918719
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving N-Acetylcysteine (NAC) intravenously soon after an acute ischemic stroke could improve outcomes. Only 4 adults with moderate to severe stroke were enrolled. Researchers measured stroke severity and disability at 30 and 90 days. The trial is complete, but the tiny size means results are very preliminary.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- N-Acetylcysteine (NAC)
- What this could lead to
- If it works, this could point toward a new treatment to reduce brain damage and improve recovery after a stroke.
- What could go wrong
- This was a very small early-phase trial with only 4 participants, so results may not apply broadly. NAC is not yet proven effective for stroke.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Harbor-UCLA Medical Center
Torrance, California, 90502, United States
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