New feeding strategy aims to cut pneumonia in severe stroke

NCT ID NCT05998902

Completed Disease control Sponsor: Wen Jiang-3 Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a combination of small amounts of tube feeding plus extra nutrition through an IV could reduce pneumonia in people with severe stroke. The trial enrolled 546 adults who had trouble swallowing. Researchers compared this approach to standard full tube feeding. The goal was to see if the mixed method lowers infection risk and improves recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Trophic enteral feeding combined with supplemental parenteral nutrition

What this could lead to

If successful, this nutrition strategy could lower the chance of pneumonia after severe stroke and improve recovery.

What could go wrong

This is a completed Phase 3 trial, but results are not yet published. The approach may not reduce pneumonia or improve outcomes for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Deglutition Disorders pneumonia stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE STROKE DYSPHAGIA SEVERE STROKE

Contacts and locations

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Locations

Chongqing University Three Gorges Hospital

Chongqing, Chongqing Municipality, 404100, China
Daping Hospital, The Third Military Medical University

Chongqing, Chongqing Municipality, China
Department of Neurology, Xijing Hospital

Xi'an, Shaanxi, China
First Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, China
Gansu Provincal Central Hospital

Lanzhou, Gansu, China
General Hospital of Ningxia Medical University

Yinchuan, Ningxia, 750000, China
Liaocheng People's Hospital

Liaocheng, Shandong, 252000, China
Nanfang Hospital, Southern Medical University

Guangzhou, Guangdong, China
People's Hospital of Xinjiang Uygur Autonomous Region

Ürümqi, Xinjiang, 830000, China
Qilu Hospital of Shangdong University

Jinan, Shandong, China
Shaanxi Second Provincal People's Hospital

Xi'an, Shaanxi, 710000, China
Shannxi Provincal People's Hospital

Xi'an, Shaanxi, China
Tangdu Hospital

Xi'an, Shaanxi, 710000, China
The Affiliated Hospital of Guizhou Medical University

Guiyang, Guizhou, 550000, China
The First Affiliated Hospital of Xi'an Medical University

Xi'an, Shaanxi, China
The First Hospital of Changsha City

Changsha, Hunan, China
The First People's Hospital of Xianyang

Xianyang, Shaanxi, China
The PLA 960 Hospital

Jinan, Shandong, China
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine

Guangzhou, Guangdong, China
The Second Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, 330000, China
The Second Affiliated Hospital of Xinjiang Medical University

Ürümqi, Xinjiang, 830000, China
The Second Hospital of Shandong University

Jinan, Shandong, China
The first affiliated hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, 710000, China
Tongji Hospital

Wuhan, Hubei, China
Xi'an Central Hospital

Xi'an, Shaanxi, 710000, China
Xi'an Gaoxin Hospital

Xi'an, Shaanxi, China
Xi'an No.3 Hospital

Xi'an, Shaanxi, China
Xianyang Hospital, Yan'an University

Xianyang, Shaanxi, 712000, China
Yulin No.1 Hospital

Yulin, Shaanxi, China
Yulin No.2 Hospital

Yulin, Shaanxi, China