New feeding strategy aims to cut pneumonia in severe stroke
NCT ID NCT05998902
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a combination of small amounts of tube feeding plus extra nutrition through an IV could reduce pneumonia in people with severe stroke. The trial enrolled 546 adults who had trouble swallowing. Researchers compared this approach to standard full tube feeding. The goal was to see if the mixed method lowers infection risk and improves recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Trophic enteral feeding combined with supplemental parenteral nutrition
- What this could lead to
- If successful, this nutrition strategy could lower the chance of pneumonia after severe stroke and improve recovery.
- What could go wrong
- This is a completed Phase 3 trial, but results are not yet published. The approach may not reduce pneumonia or improve outcomes for all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chongqing University Three Gorges Hospital
Chongqing, Chongqing Municipality, 404100, China
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Daping Hospital, The Third Military Medical University
Chongqing, Chongqing Municipality, China
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Department of Neurology, Xijing Hospital
Xi'an, Shaanxi, China
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First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
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Gansu Provincal Central Hospital
Lanzhou, Gansu, China
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General Hospital of Ningxia Medical University
Yinchuan, Ningxia, 750000, China
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Liaocheng People's Hospital
Liaocheng, Shandong, 252000, China
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Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China
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People's Hospital of Xinjiang Uygur Autonomous Region
Ürümqi, Xinjiang, 830000, China
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Qilu Hospital of Shangdong University
Jinan, Shandong, China
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Shaanxi Second Provincal People's Hospital
Xi'an, Shaanxi, 710000, China
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Shannxi Provincal People's Hospital
Xi'an, Shaanxi, China
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Tangdu Hospital
Xi'an, Shaanxi, 710000, China
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The Affiliated Hospital of Guizhou Medical University
Guiyang, Guizhou, 550000, China
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The First Affiliated Hospital of Xi'an Medical University
Xi'an, Shaanxi, China
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The First Hospital of Changsha City
Changsha, Hunan, China
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The First People's Hospital of Xianyang
Xianyang, Shaanxi, China
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The PLA 960 Hospital
Jinan, Shandong, China
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The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Guangzhou, Guangdong, China
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The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 330000, China
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The Second Affiliated Hospital of Xinjiang Medical University
Ürümqi, Xinjiang, 830000, China
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The Second Hospital of Shandong University
Jinan, Shandong, China
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The first affiliated hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, 710000, China
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Tongji Hospital
Wuhan, Hubei, China
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Xi'an Central Hospital
Xi'an, Shaanxi, 710000, China
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Xi'an Gaoxin Hospital
Xi'an, Shaanxi, China
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Xi'an No.3 Hospital
Xi'an, Shaanxi, China
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Xianyang Hospital, Yan'an University
Xianyang, Shaanxi, 712000, China
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Yulin No.1 Hospital
Yulin, Shaanxi, China
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Yulin No.2 Hospital
Yulin, Shaanxi, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Which is safer for frail seniors: sedation or no sedation during feeding tube placement?
- A Pocket-Sized MRI for strokes? new device put to the test
- Does a dedicated stroke unit boost recovery after a first stroke?
- Breathing exercises may retrain swallowing in ICU survivors — a trial puts it to the test
- Zapping the brain to restore swallowing after stroke