New stroke device aims to restore blood flow in distal brain clots

NCT ID NCT05152524

Completed Disease control Sponsor: Rapid Medical Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 13, 2026 · Updated 3 times

Summary

This trial tests a device called Tigertriever 13 to treat distal ischemic strokes, where a blood clot blocks a small artery deep in the brain. About 168 patients with disabling symptoms will receive either the device or standard medical care within 24 hours of stroke onset. The goal is to see if the device safely restores blood flow and improves outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Tigertriever 13 device
What this could lead to: If successful, this device could offer a new treatment option for distal ischemic strokes, potentially improving blood flow and reducing disability.
What could go wrong: This is an early-stage study with 168 participants, so results may not apply to everyone. There are risks of bleeding or other complications from the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cerebral artery occlusion ischemic stroke Neovascularization, Pathologic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIC STROKE NEOVASCULARIZATION

Contacts and locations

Locations

Advocate Aurora Research Institute,

Chicago, Illinois, 60657, United States
Alfreid Krupp

Essen, Germany
CUB Hôpital Erasme

Brussels, 1070, Belgium
Corewell Health (Spectrum)

Grand Rapids, Michigan, 49085, United States
Lakewood Regional Medical Center

Los Angeles, California, 90013, United States
Los Robles

Thousand Oaks, California, 91360, United States
Mercy Health

Toledo, Ohio, 43604, United States
Mount Sinai

New York, New York, 10029, United States
Munson Medical Center

Traverse City, Michigan, 49684, United States
NYU Langone Health

New York, New York, 10016, United States
Orebro University Hospital

Örebro, Sweden
Semmes Murphey Foundation

Memphis, Tennessee, 38120, United States
St. Lukas hospital, Radprax

Solingen, Solingen, 42697, Germany
Stony Brook University

Stony Brook, New York, 11794, United States
Texas Stroke Institute

Plano, Texas, 75075, United States
University of Buffalo

Buffalo, New York, 14203, United States
Universitätsklinikum Bonn

Bonn, 53127, Germany
Universitätsklinikum Schleswig-Holstein

Kiel, Germany
Valley Baptist Medical Center

Harlingen, Texas, 78550, United States
WellStar Research Institute

Marietta, Georgia, 30060, United States

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