Brain protection during carotid surgery: new procedure shows promise
NCT ID NCT06359756
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed clinical trial tested a procedure called ischemic postconditioning to prevent brain damage in 40 people undergoing carotid surgery for severe artery narrowing. The procedure involves briefly clamping and unclamping the carotid artery in cycles after surgery to protect the brain. Researchers measured brain oxygen levels, blood flow, and markers of brain injury to see if the technique is safe and effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ischemic postconditioning (a procedure involving brief cycles of clamping and unclamping the carotid artery during surgery)
- What this could lead to
- If this procedure proves effective, it could offer a simple way to reduce the risk of stroke and brain damage during carotid surgery.
- What could go wrong
- This is a very small, completed trial with only 40 participants, so results may not apply to everyone. The procedure itself involves temporary clamping of the artery, which carries its own risks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Institute for Cardiovascular Diseases Dedinje
Belgrade, 11000, Serbia
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