Brain protection during carotid surgery: new procedure shows promise

NCT ID NCT06359756

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed clinical trial tested a procedure called ischemic postconditioning to prevent brain damage in 40 people undergoing carotid surgery for severe artery narrowing. The procedure involves briefly clamping and unclamping the carotid artery in cycles after surgery to protect the brain. Researchers measured brain oxygen levels, blood flow, and markers of brain injury to see if the technique is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ischemic postconditioning (a procedure involving brief cycles of clamping and unclamping the carotid artery during surgery)

What this could lead to

If this procedure proves effective, it could offer a simple way to reduce the risk of stroke and brain damage during carotid surgery.

What could go wrong

This is a very small, completed trial with only 40 participants, so results may not apply to everyone. The procedure itself involves temporary clamping of the artery, which carries its own risks.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

carotid artery disorder carotid stenosis stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institute for Cardiovascular Diseases Dedinje

    Belgrade, 11000, Serbia