Can a common supplement curb stroke damage?
NCT ID NCT07749287
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This phase 3 trial investigates whether N-acetyl cysteine (NAC), an antioxidant supplement, can improve recovery in people hospitalized with an acute ischemic stroke. Participants receive either NAC or a placebo (saline) shortly after admission, and researchers track their neurological function and markers of inflammation. The goal is to see if NAC can reduce stroke-related disability and dampen the body's harmful inflammatory response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- N-acetyl cysteine (NAC) given as a 600 mg oral solution every 8 hours for 3 days after hospital admission
- What this could lead to
- If NAC proves effective, it could offer a simple, widely available treatment to improve recovery and reduce disability after an acute ischemic stroke.
- What could go wrong
- This is a single-center trial with a modest number of participants, and results may not generalize. NAC's benefits beyond standard care remain uncertain, and it is not a replacement for clot-busting drugs when those are appropriate.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Stroke Unit, Neurology Department, Kasr Al Ainy, Cairo University Hospital
Cairo, Egypt
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