Blood test could unlock stroke treatment for thousands

NCT ID NCT03364296

Completed Diagnosis Sponsor: Central Hospital, Nancy, France Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether measuring two proteins in the blood (GST-π and PRDX1) can accurately determine if a stroke occurred within the last 4.5 hours. That time window is critical because it determines if patients can receive clot-busting medication. Researchers enrolled 935 adults with stroke symptoms to test this approach. If it works, it could help treat people who wake up with a stroke or don't know exactly when symptoms started.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could give doctors a simple blood test to quickly determine when a stroke began, allowing more patients to receive timely clot-busting treatment.
What could go wrong: This is an early diagnostic study, not a treatment trial. The blood markers may not be accurate enough in real-world settings, and results may not change current practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STROKE, ACUTE

Contacts and locations

Locations

Centre Hospitalier de Bar-Le-Duc

Bar-le-Duc, 55000, France
Centre Hospitalier de Troyes

Troyes, 10003, France
Centre Hospitalier de Verdun

Verdun, 55300, France
Fondation Adolphe de Rothschild

Paris, 75019, France
Hôpital Central

Nancy, 54000, France

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