Spinal tap may offer headache relief for brain bleed survivors

NCT ID NCT03754335

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether draining some fluid from the spine (a lumbar puncture) can help relieve severe headaches that often follow a brain aneurysm rupture. The trial involved 74 patients with mild to moderate brain bleeds. Half received a real lumbar puncture, and half received a sham procedure, with both groups also getting standard pain medication. The goal was to see if the fluid removal reduced headache intensity more than the sham procedure.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
lumbar puncture (spinal tap)
What this could lead to
If it works, this could provide a simple, safe way to reduce severe headaches after a brain aneurysm bleed, improving patient comfort.
What could go wrong
This is a small, completed trial with only 74 participants. The procedure may not significantly reduce pain compared to standard care, and there are risks like infection or bleeding from the lumbar puncture.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Toulouse

    Toulouse, 31059, France

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