Which blood pressure drug keeps the brain better oxygenated during carotid surgery?
NCT ID NCT01794273
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This trial compares two medications, ephedrine and phenylephrine, used to treat sudden low blood pressure during carotid surgery. The main question is whether one drug better preserves oxygen levels in the brain during the procedure. The study involves adults undergoing planned carotid surgery under general anesthesia who experience low blood pressure. Researchers will also monitor for side effects like further drops in blood pressure or slow heart rate, as well as recovery after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ephedrine and phenylephrine
- What this could lead to
- If one drug proves better at maintaining brain oxygen during surgery, it could become the preferred choice for managing blood pressure in this setting, potentially improving patient outcomes.
- What could go wrong
- This is a single-center trial with a modest number of participants, so results may not apply broadly. Both drugs have known side effects, including effects on heart rate and blood pressure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Clermont-Ferrand
Clermont-Ferrand, 63003, France