Lifting weights to save your brain: study tests resistance training against cognitive decline

NCT ID NCT02669394

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether a year of twice-weekly resistance training could protect brain health and thinking skills in 91 older adults with vascular cognitive impairment, a condition linked to small strokes. Participants were randomly assigned to either resistance training or a stretching and relaxation program. The researchers measured changes in cognitive function and brain white matter lesions to see if exercise could slow disease progression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
resistance exercise training
What this could lead to
If successful, this could point toward a simple, drug-free way to slow cognitive decline in people with vascular cognitive impairment.
What could go wrong
This is a small, early proof-of-concept study, not a large definitive trial. The benefits may be modest or not apply to everyone, and exercise programs require long-term commitment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of British Columbia

    Vancouver, British Columbia, V5Z 1M9, Canada

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