Smart wire could reveal clot secrets during stroke treatment

NCT ID NCT04993079

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This first-in-human study tested a new smart guidewire (Clotild®) in 45 stroke patients undergoing emergency clot removal. The wire helps guide the removal tool and also measures the clot's electrical properties to determine its composition. The main goal was to check safety, such as whether the wire causes blood vessel damage, and to see if it can accurately tell what the clot is made of.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Clotild® Smart Guidewire System (a device used to guide clot removal tools and measure clot characteristics)

What this could lead to

If successful, this device could help doctors better understand clot composition during stroke treatment, potentially improving future clot removal procedures.

What could go wrong

This is a very early, small study focused on safety and feasibility. The device may not provide useful measurements or could cause vessel injury. Results may not apply to all stroke patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Limoges

    Limoges, 87000, France

  • Gold Coast University Hospital

    Southport, Queensland, QL 5215, Australia

  • Liverpool Hospital

    Liverpool, New South Wales, NSW 2170, Australia