Nutritional disorder

This study tests whether a pharmacist-led education program can help women with hypothyroidism and low vitamin D levels improve their vitamin D levels and medication habits. Sixty women will be split into two groups: one receives standard care, the other gets counseling, brochure…

This trial tests whether online group dialectical behavioral therapy (DBT) is as effective as traditional face-to-face group DBT for women with bulimia nervosa. Participants will be randomly assigned to either 12 weeks of online or in-person group therapy, and researchers will co…

This study looked at whether tiny plastic particles (microplastics) we encounter daily might contribute to obesity and gut problems. Researchers gave 96 overweight or obese adults either a probiotic supplement or a placebo to see if the probiotic could reduce the harmful effects …

This phase 2b trial tests a weekly oral tablet called ecnoglutide (VRB-101) for weight loss in 206 adults with obesity or overweight plus weight-related health problems. Participants receive either the drug or a placebo for several weeks. The main goal is to see how much body wei…

This trial tests whether giving oral antibiotics alongside a therapeutic food improves recovery in young children with severe acute malnutrition (kwashiorkor or marasmus). Children aged 6 months to 5 years who qualify for home-based feeding will receive either amoxicillin, cefdin…

This study tests a program called Fit Together that combines standard medical care with community activity sessions for children with obesity. About 400 children aged 5-12 will receive a referral to local park programs offering exercise, sports, and nutrition activities. Research…

This pilot study explores whether adding a cognitive training game called PolyRules! to the WW (formerly Weight Watchers) online program can help adults with overweight or obesity lose more weight. Participants will either follow the WW program alone or combine it with the brain-…

This Phase 3 trial is testing whether a once-daily 50 mg semaglutide tablet can help East Asian adults with overweight or obesity lose weight. Participants will take either the active tablet or a placebo for 68 weeks, alongside lifestyle counseling on diet and physical activity. …

This study is testing a postbiotic supplement called resM™ GLP-1 Postbiotic to see if it helps overweight adults lose weight and improve their metabolic health. The supplement contains vitamins, minerals, and plant extracts. Researchers will measure changes in weight, BMI, food c…

This study tests whether a supplement made from brown algae and chromium picolinate, when added to a calorie-controlled Mediterranean diet, can reduce fat buildup in the liver. Adults with metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic syndrome wil…

This study tested whether taking extra leucine, a natural amino acid, helps preserve muscle during a 4-week alternate-day fasting program in overweight young men. Participants were randomly assigned to one of four doses of leucine. Researchers measured body composition, blood mar…

This trial follows women with polycystic ovary syndrome (PCOS) who take metformin, a standard diabetes medication, for six months. Researchers track changes in insulin resistance, iron levels, erythropoietin, cholesterol, and blood counts at three and six months. The goal is to s…

This study tests whether restricting carbohydrates on two consecutive days per week or after 4pm each day can improve metabolic health and energy balance in adults with abdominal overweight or obesity. Over four weeks, participants follow one of these eating patterns or their usu…

This trial tests whether a web-based program called PATH can help adults with obesity become more physically active and stick to recommended exercise levels. Participants are randomly assigned to either the PATH program, which includes personalized coaching and online resources, …

This trial is testing whether a compound called sodium pentaborate pentahydrate can help people with overweight or obesity lose weight and improve their blood sugar. Participants will receive either the compound or a placebo, and researchers will track changes in body weight, wai…

This study tests a program that helps people with obesity who are waiting for a kidney transplant lose weight. Participants will receive education, a calorie tracking app, a continuous glucose monitor, a weight scale, and a food scale. The goal is to see if this program is practi…

This study tests whether survodutide, a weekly injection for weight loss, is safe for the heart in people who are overweight or obese and have heart or kidney disease. About 5,500 adults will receive either survodutide or a placebo for up to 2 years, along with diet and exercise …

This study looks at whether giving tranexamic acid during weight-loss (bariatric) surgery can reduce bleeding. Researchers will compare patients who received the drug with those who did not, focusing on drops in hemoglobin levels, need for transfusions, hospital stay length, and …

This study tested a lifestyle program to help pregnant women with obesity maintain their weight and lose body fat during pregnancy. About 100 women in early pregnancy took part, receiving either the program or standard care. The goal was to see if the program could improve mother…

This study gives overweight teens ages 12-17 free weekly produce from a local farm for 8 weeks, along with educational videos. Researchers want to see if this program is practical and if it increases fruit and vegetable intake, improves blood pressure, and helps with weight. Fift…

This study tests an experimental daily pill called aleniglipron for weight loss in 220 adults with obesity or overweight who also have a weight-related health issue. Participants receive either the drug or a placebo for 36 weeks, with the option to continue on the drug for anothe…

This study tests whether the drug lisdexamfetamine (Vyvanse), usually used for ADHD, can help children aged 6 to 12 with severe obesity lose weight. About 44 children will receive either the drug or a placebo, plus lifestyle therapy, for 24 weeks. The main goal is to see if their…

This study tested an experimental oral medication called TERN-601 in 167 adults with overweight or obesity. The goal was to see if it helps with weight loss over 12 weeks compared to a placebo. Participants did not have diabetes and had a stable weight before starting. The study …

This trial tests whether a 12-week calorie-restricted diet, combined with the weight-management drug Contrave, can help people with type 2 diabetes and obesity achieve remission. Remission means blood sugar levels drop below the diabetes threshold without needing glucose-lowering…

This trial tests whether a 12-week program of eccentric cycling—where muscles lengthen under load, like pedaling against resistance—can reduce body fat in overweight and obese teenagers more effectively than traditional concentric cycling. The study compares both types of exercis…

This trial tests whether time-limited eating—consuming all food and drinks within an 8-hour period and fasting for the remaining 16 hours—can improve blood sugar control, insulin function, and body fat in adolescents with type 2 diabetes. Participants aged 12 to 21 will follow th…

This phase 3 trial is testing a drug called setmelanotide in people with obesity linked to certain gene variants (POMC, PCSK1, LEPR, NCOA1, or SH2B1). About 296 participants, aged 6 to 65, will receive either the drug or a placebo to see if it helps reduce body weight. The study …

This study tested a new medicine called survodutide (BI 456906) to see if it helps people with overweight or obesity and type 2 diabetes lose weight. Over 750 adults received either the drug or a placebo injection once a week for about 76 weeks, along with diet and exercise advic…

This study looks at whether a follow-up surgery called Single Anastomosis Duodenal Ileal Bypass (SADI) can help people who had a sleeve gastrectomy but didn't lose enough weight. Participants are adults with severe obesity who lost less than 10% of their body weight after the fir…

This trial tests whether a single yogurt drink made from vegetable proteins rich in leucine, cysteine, and arginine can improve blood vessel function and reduce inflammation in older adults with cardiometabolic risk. Participants, aged 65 and older, will consume either the vegeta…

This pilot trial tests whether easier or harder daily goals in a digital weight loss program are more feasible and acceptable for adults with overweight or obesity. Participants receive a 10-week remote program with self-monitoring tools and are assigned different goal intensitie…

This trial tests whether a 'food as medicine' program can help people with diabetes better control their blood sugar. Participants receive weekly medically tailored meals, nutrition classes led by dietitians, and vouchers for fresh produce. The study will measure changes in HbA1c…

This study tests whether a DASH diet—a plan rich in fruits, vegetables, and low-fat dairy—can help menopausal women with metabolic syndrome lose weight and improve health markers like blood pressure, cholesterol, and blood sugar. Researchers will also check if certain gene variat…

This trial tests whether the type of physical activity—resistance, endurance, or a mix—combined with a low-calorie diet can reduce belly fat and cardiovascular risk in people with metabolic syndrome. Adults aged 50-70 with metabolic syndrome are randomly assigned to one of three …

This trial tests whether doing a short bout of exercise right before or right after a meal changes how much adolescents with obesity eat and how hungry they feel. Teens aged 12-16 will either rest or exercise at specific times, then eat a buffet meal where their intake is measure…

This study looks at whether bariatric (weight-loss) surgery can reduce the risk of heart attacks, strokes, heart failure, and death in people who have both type 2 diabetes and obesity. It compares people who had the surgery with those who received usual diabetes care. The goal is…

This study looked at how a weekly injection of semaglutide (2.4 mg) affects appetite, eating behavior, and mood in 120 adults with obesity. All participants also received lifestyle counseling on diet and exercise. The goal was to see if semaglutide reduces calorie intake and impr…

This trial asks whether the amount of daily energy turnover—how much energy is used through diet and exercise—can influence appetite and food reward in adolescents with obesity. Eighteen teens aged 12-16 will each complete three sessions with low, moderate, or high energy turnove…

This trial tests whether taking polyphenol supplements with a meal can reduce how much iron the body absorbs in people with iron overload disorders like genetic hemochromatosis and dysmetabolic iron overload syndrome. Participants eat a standardized iron-rich meal with either pol…

This trial tests whether a smartphone app called Kiplin, which uses games, telecoaching, and social support, can increase daily physical activity in people with obesity or type 2 diabetes. It compares the app to a standard three-month face-to-face exercise program. The main goal …

This trial tests whether ferric maltol, an oral iron supplement, can safely raise hemoglobin levels in adults with inflammatory bowel disease (IBD) who have iron deficiency anemia and have not responded to or cannot tolerate standard ferrous iron pills. Participants take either f…

This trial tests whether taking a daily supplement of cornelian cherry fruit for six months can improve markers of heart, blood vessel, eye, and bone health in people with metabolic syndrome. Participants will receive either the cherry supplement or a placebo, and researchers wil…

This trial tests whether time-restricted eating (TRE) — limiting all food intake to an 8-10 hour daily window — can improve blood sugar control and metabolic health in people with metabolic syndrome or prediabetes. Participants are randomly assigned to either standard nutritional…

This Phase 3 study tests a weekly injection called retatrutide in about 1,946 people with severe obesity (BMI ≥35) and established heart disease. The goal is to see if it helps with weight loss and improves heart-related health measures over 113 weeks compared to a placebo. Parti…

This trial investigates whether eating 1.5 ounces of pecans every day for eight weeks can improve blood sugar, cholesterol levels, and body composition in adults who are overweight or obese. Participants will be randomly assigned to either the pecan group or a control group that …

This pilot study tests whether laparoscopic sleeve gastrectomy, a weight-loss surgery, can reduce markers of inflammation in saliva and improve gum health in adults with both obesity and periodontitis (gum disease). Participants are randomly assigned to either surgery or non-surg…

This 12-month trial compares two weight-loss strategies in adults with obesity: eating only between 12 pm and 8 pm each day (an 8-hour time-restricted eating window) versus reducing daily calories by 25%. A control group follows no specific diet. The study measures changes in bod…

This phase 3 trial is testing whether an experimental oral drug called HRS-7535 can help people with overweight or obesity lose weight. About 556 adults aged 18 to 75 with a body mass index (BMI) of 24 or higher (or 28 or higher) are taking either HRS-7535 or a placebo daily. Res…

This trial tests whether standing on a vibrating platform for short sessions, twice a week, can boost heat production (thermogenesis), improve heart health markers, and reduce inflammation in adults with obesity. Participants will be assigned to one of two types of vibrating plat…

This study tests whether a moderately low-carb diet can reduce liver fat and improve how the body uses insulin in teenagers with non-alcoholic fatty liver disease (NAFLD) and obesity. About 80 teens aged 10-17 will follow either a carb-restricted or a low-fat diet for 6 months, w…

This study looks at whether a vegan protein supplement made from buriti fruit, rice, and pea can improve body composition, flexibility, and balance in women aged 60 and older who regularly practice Tai Chi. Forty participants will receive either the supplement or a placebo for 12…

This trial tests whether intermittent energy restriction (alternating normal and reduced-calorie days) works better than continuous daily calorie cutting for weight loss in women with obesity. Researchers will measure changes in body fat, muscle mass, and metabolic adaptation — t…

This pilot trial tests whether a program of walking, dance, and abdominal core workouts can improve certain health markers in adults with obesity who are not very active. The program, called PATH, is designed to be enjoyable and stigma-free, focusing on general health benefits ra…

This trial investigates whether a daily probiotic supplement called Bifidobacterium longum BL21 can help overweight or obese adults lower their body mass index (BMI) and improve metabolic health. Over 8 weeks, participants take either the probiotic or a placebo, and researchers t…

This phase 1 trial compares how well three different versions of the experimental drug AMG 133 (maridebart cafraglutide) are absorbed after a single injection in people with overweight or obesity. The study involves 154 adults aged 18 to 65 with a body mass index between 25 and 4…

This study looked at 1331 women aged 18-45 who had low iron stores but normal hemoglobin (no anemia). They were split into three groups: one got daily oral iron pills for 3 months, another got three IV iron infusions over 3 months, and a third got no treatment. The goal was to se…

This study tests whether personalized motivational text messages can help adults with anorexia nervosa increase their motivation to change and their calorie intake. Participants receive these texts alongside cognitive behavioral therapy (CBT), which is provided at no cost. The st…

This study tests an experimental once-daily oral drug called orforglipron in Japanese adults with obesity and related health problems like high blood pressure or type 2 diabetes. Participants receive either orforglipron or a placebo for 72 weeks. The main goals are to measure wei…

This study tests two versions of cognitive behavioral therapy (CBT) for adult women with a specific form of bulimia nervosa that also involves borderline personality traits. One therapy focuses only on eating disorder symptoms, while the other also addresses mood and relationship…

This study tests whether orforglipron, an experimental oral drug for weight management, works the same when given as a tablet versus a capsule. Healthy adults with a BMI between 27 and 40 take the drug for about 22 to 25 weeks, and researchers measure how much of the drug enters …

This study tests an experimental oral drug called LY3502970 in Chinese adults who have obesity or are overweight with related health problems like high blood pressure or sleep apnea. The main goal is to check the drug's safety and how the body processes it. Participants receive e…

This study tests whether training mothers to measure their child's mid-upper arm circumference (MUAC) each week can spot severe malnutrition relapse sooner. Children aged 6 to 59 months who have recently recovered from severe acute malnutrition are enrolled. Mothers learn to use …

This study tests an experimental drug called GZR18, given as an injection every two weeks, to help people with obesity or overweight lose weight. It compares three doses of GZR18 against a placebo and an existing weekly weight-loss drug, tirzepatide. Participants do not have type…

This study looks at whether heart failure patients with iron deficiency anemia respond better to oral iron supplements when they are also taking a type of heart medication called SGLT2 inhibitors. Participants take oral iron for three to four months, then pause treatment while do…

This study tests whether adding a modified traditional Chinese herbal formula, Huanglian Wendan Decoction, to standard lifestyle and drug therapy can reduce oxidative stress in people with metabolic syndrome. About 180 adults will receive either standard care alone or standard ca…

This study investigates whether the type of dietary protein (animal or vegetable) and energy restriction can improve insulin resistance in adults with obesity. Over one month, participants follow a controlled diet with either standard or high protein from animal or vegetable sour…

This study looks at whether a traditional Islamic practice—fasting from dawn to sunset every Monday and Thursday for 8 weeks—can improve gut health, appetite control, and body composition in obese adult men. Participants follow the fast without any other diet changes, while resea…

This trial investigates a surgical procedure for people with type 2 diabetes and mild obesity (grade 1). The surgery combines three steps: rerouting part of the small intestine, reducing the stomach size, and cutting certain abdominal nerves. The goal is to see if this approach c…

This study investigates whether adding foxtail millet muffins to the diet can help manage blood sugar and improve metabolic health in obese adults with type 2 diabetes. Over 10 weeks, participants eat either a wheat muffin or one or two foxtail millet muffins daily, alongside a l…

This trial investigates whether adding β-sitosterol, a natural plant sterol, to the diet can improve cholesterol levels in adults with grade II obesity and high cholesterol. Participants follow a controlled diet, with one group receiving β-sitosterol-enriched foods. The study mea…

This trial compares robotic and laparoscopic sleeve gastrectomy in people with obesity to see which approach is faster and safer. Participants are randomly assigned to one of the two surgical methods. The study measures operative time, bleeding, and complications like leaks or co…

This study looks at how different diets—ketogenic, intermittent fasting, and semi-vegetarian—affect weight, body fat, and metabolism in women with obesity, both alone and with a home exercise program. Over 6 weeks, 108 women aged 19-45 will be split into nine groups to compare re…

This early-stage study tests an experimental oral drug called LY3502970 in healthy adults who are overweight or obese. The main goal is to see how the drug enters the bloodstream and how the body clears it, as well as to check for any safety issues. Participants will take the dru…

This study tests whether a remotely delivered lifestyle education program can help people who have lost weight with medication keep that weight off after they stop taking the drugs. Participants are adults who lost at least 5% of their body weight during a previous pharmacotherap…

This study looks at health records of 120,000 people with type 2 diabetes and overweight to compare two injectable drugs: semaglutide and dulaglutide. Researchers want to see which one better reduces the risk of death, heart attack, or stroke. The goal is to understand how these …

This study compares two popular weight-loss medications, tirzepatide and semaglutide, in 100,000 adults who are overweight or obese and at risk for heart problems but do not have diabetes. Researchers are analyzing real-world data to see which drug better prevents death, heart at…

This study tests whether a 3-month community program combining nutrition education, cooking classes, and exercise can improve health outcomes for people with Cardiovascular Kidney Metabolic (CKM) syndrome—a cluster of conditions including diabetes, high blood pressure, high chole…

This completed trial tested whether laser acupuncture could improve body shape index (ABSI) in 50 women aged 40-50 with uncontrolled type 2 diabetes and obesity. Participants received either real or sham laser acupuncture twice a week for 12 weeks, plus a low-glycemic diet. The s…

This phase 2 study tests whether bimagrumab, a drug that blocks a protein involved in muscle loss, can help overweight or obese adults lose more weight when used alone or alongside semaglutide (the drug in Wegovy and Ozempic). The trial includes about 500 men and women aged 18 to…

This study tests whether the weight-loss drug tirzepatide can increase the activity of brown and beige fat—special fat cells that burn energy instead of storing it. The trial includes women with obesity who will receive either tirzepatide or a placebo for 24 weeks. Researchers wi…

This phase 3 study tests an investigational drug called HM11260C for weight loss in adults with obesity who do not have diabetes. Participants must have a body mass index (BMI) of 30 or higher, or a BMI of 27 or higher with related health issues like high blood pressure. The tria…

This study evaluates a comprehensive treatment model for eating disorders like anorexia, bulimia, and binge eating. The ITA model combines outpatient therapy, day hospital, and hospitalization tailored to each patient's needs. Researchers will track changes in symptoms and well-b…

This study investigates whether 12 weeks of moderate aerobic exercise can improve heart health, metabolism, and menopause symptoms in postmenopausal women who have two or more chronic conditions like high blood pressure and high cholesterol. Participants will exercise three times…

This study tests an artificial intelligence (AI) health coach that provides real-time, personalized weight management support through a smartphone app. Adults with overweight or obesity wear a fitness tracker and use the app to get tips on physical activity, sleep, diet, and heal…

This study investigates whether a daily fiber supplement called inulin, extracted from Thai Jerusalem artichoke, can change the gut bacteria and reduce body fat in obese children aged 7 to 15. Over six months, one group receives inulin, another gets a placebo, and a third group r…

This study investigates whether a structured, personalized exercise plan—tracked with a smartwatch and supported by regular phone check-ins—can help control blood sugar, blood pressure, and weight gain in pregnant women with gestational diabetes, chronic hypertension, or obesity.…

This study tests whether combining lifestyle counseling with weight-loss medication helps teens aged 12–17 with severe obesity lose weight. About 120 participants will receive counseling and medication for a year. The goal is to find a practical, effective treatment that is easie…

This study tests whether adding a canine health-literacy module to an existing family lifestyle program helps overweight teens and their parents become more active. The program includes lessons on dog care, behavior, and exercise, along with activity trackers and surveys. Partici…

This study investigates whether cryolipolysis, a non-invasive fat freezing technique, can lower inflammatory markers in obese postmenopausal women. Participants are women aged 50-60 with a BMI of 30-40. The treatment is applied to the lower belly for 30 minutes, and researchers m…

This study investigates whether adding whole-body electrical muscle stimulation (WB-EMS) to a calorie-restricted diet improves body composition and metabolic health in women with obesity. Participants follow an 8-week diet plan, with half also receiving twice-weekly 20-minute WB-…

This study explores whether combining a high-protein Mediterranean diet with resistance exercise can help people with heart disease build muscle and lower their risk of future heart problems. The trial enrolls adults who have completed cardiac rehab and may have low muscle mass w…

This study tests whether a single intravenous dose of ferumoxytol raises hemoglobin more effectively than daily oral ferrous sulfate in pregnant women with iron deficiency anemia. Participants are between 24 and 34 weeks pregnant with a single baby. The trial measures hemoglobin …

This trial investigates whether changing how often and when people with type 2 diabetes eat can improve weight, blood sugar, and cholesterol. Over 12 weeks, participants follow one of three eating plans: a standard 6-meal diet, a 3-meal diet, or time-restricted eating (eating all…

This study looks at whether specially designed nutritional supplements can improve thinking skills and emotional control in young children in Bangladesh who have moderate malnutrition. About 300 children aged 1 to 3 years receive either standard or enhanced nutritional supplement…

This trial investigates whether anemic patients scheduled for hip or knee replacement surgery benefit from taking an iron supplement (Sideremil Vita) for 30 days before the operation, compared to taking it for only 15 days. The goal is to see if the longer treatment reduces the n…

This study investigates whether giving vitamin D supplements to adults with inflammatory bowel disease (Crohn's disease or ulcerative colitis) who also have low vitamin D levels can improve their iron status. Participants take high-dose vitamin D3 weekly for 8 weeks, then a lower…

This study tested a 12-week program for Hispanic mothers with overweight or obesity and their 3-5 year old children. The program included weekly classes on nutrition, exercise, and coping skills, plus exercise sessions. Researchers measured changes in weight, body fat, and health…

This completed pilot study tested whether transferring gut bacteria from lean donors or from people who had gastric bypass surgery could improve metabolism in 29 obese adults with prediabetes or diabetes. Participants received fecal transplants, and researchers measured changes i…

This phase 2 study tested a new drug called eloralintide (LY3841136) for weight management in 263 adults with obesity or overweight. Participants received either the drug or a placebo for about 64 weeks. The main goal was to see how much weight they lost after 48 weeks. Results w…

This study tested whether a low glycemic index (GI) diet helps overweight Chinese teenagers lose weight and improve health. 285 adolescents followed either a low-GI or regular Chinese diet for 12 months. Researchers measured changes in body mass index, body fat, and heart-related…

This study tests whether a dietary supplement called Satisens®, made from lemon verbena, hibiscus, saffron, and carob extract, can help reduce emotional eating and cravings for sweets in healthy adults who are overweight or obese. Participants take two capsules daily for a set pe…

This trial investigates whether adding hypnosis sessions to standard dietary monitoring can help people lose weight after bariatric surgery has not worked. About 25% of patients do not achieve lasting weight loss from surgery alone. The study enrolls 60 adults aged 18-65 with obe…

This study tested whether eating probiotic-enriched pasta daily for 4 weeks could improve metabolic health and reduce inflammation in overweight and obese adults. Forty healthy men and women with a BMI between 25 and 35 ate either probiotic pasta or regular pasta. Researchers mea…

This study looks at whether using a continuous glucose monitor (CGM) alongside standard nutrition and activity advice can improve metabolic health in young people aged 11 and older who have prediabetes and are overweight. Participants wear the CGM intermittently to see how daily …

This small pilot study tested the safety of a swallowable intra-gastric balloon (IGBalloon) for weight loss in 5 people with obesity. Participants swallowed up to 5 balloons over 8 weeks, with regular check-ups including blood tests and endoscopies. The study also looked at weigh…

This study tested whether an iron injection works better than iron pills for treating anemia in 200 new mothers within 10 days of giving birth. Participants had mild to moderate anemia and were randomly assigned to receive either a single injection of ferric carboxymaltose or ora…

This study tested whether giving rewards like gift cards can help Native American women quit smoking and lose weight. 125 women who smoked daily and were overweight or obese took part. They earned prizes for staying smoke-free and losing a half to one pound per week. The goal was…

This study looked at whether a supervised exercise program, started 3 months after bariatric surgery, helps improve body composition, muscle strength, and insulin resistance. 61 adults with severe obesity took part. Participants were randomly assigned to either an exercise group …

This study tested whether adding a structured treadmill walking program to standard iron therapy improves exercise tolerance and quality of life in young women with mild-to-moderate iron deficiency anemia. Sixty women aged 18-28 were split into two groups: one received iron suppl…

This study tested a culturally adapted online program for families with overweight or obese children aged 7-9 in Vietnam. The program aimed to improve parents' confidence and healthy role modeling, and children's eating habits, physical activity, and body measurements. Sixty fami…

This study looked at whether giving protein supplements after sleeve gastrectomy surgery helps patients keep their muscle mass while losing weight. 90 obese adults who had the surgery took part. Researchers measured changes in lean body mass and other health markers over 5 weeks.

This study tested a 16-week weight-loss program using the drug tirzepatide before elective hernia surgery in 91 adults with obesity. Participants lost an average of 13.8% of their body weight, and all reached the target weight needed for surgery. Compared to a similar group who h…

This study tested whether giving babies one egg daily along with teaching parents about responsive feeding, nutrition, and hygiene can improve growth and development. 600 infants in Haiti were split into three groups: standard care, eggs only, or eggs plus the parenting program. …

This study tested whether a school-based gardening, nutrition, and cooking program could help low-income Hispanic children eat more vegetables and maintain a healthy weight. Over 3,000 students in 16 Texas elementary schools took part, with some schools getting the program and ot…

This study tested whether a diet focused on low-energy-density foods (like fruits, vegetables, and broth-based soups) helps people maintain weight loss better than simply counting calories. 345 adults with obesity were followed for 22 months. Researchers measured changes in weigh…

This study tested a new medicine called HS-20094 to help overweight and obese adults lose weight. About 600 people took either the drug or a placebo for up to 48 weeks. The main goals were to see how much weight they lost and how many lost at least 5% of their starting weight.

This study tested whether bars made with polyunsaturated fatty acids could improve cholesterol and fat levels in people with metabolic syndrome. 60 adults aged 40-65 with high BMI and abnormal cholesterol took part. The goal was to see if these bars could help control dyslipidemi…

This Phase 2 study tested an investigational drug called HS-20094 in 200 overweight or obese adults. Participants received either the drug or a placebo injection over several weeks. The main goal was to see how much weight they lost and whether the drug was safe.

This study tested whether a telemedicine program for children with obesity works better than standard in-person care. 100 children aged 10-18 were split into two groups: one received most of their care through video calls, and the other had monthly in-person visits. The main goal…

This early study tested a single injection of a new drug called ENT-03S in 49 people who were either obese but otherwise healthy, or had both obesity and type 2 diabetes. The main goal was to check safety and how the drug moves through the body. Participants were randomly assigne…

This study tested whether daily cassava root and sesame seed granules, along with nutrition education, could improve the nutritional health of adults with HIV. Sixty-four participants took part, receiving either the granules plus education or education alone for 16 weeks. The goa…

This study followed 543 adults aged 18-60 who had bariatric surgery at four hospitals in Norway. Each hospital used a different surgical method, allowing researchers to compare how well each approach helped with weight loss and type 2 diabetes remission. The goal was to find whic…

This large Phase 3 trial tested a once-weekly injection called retatrutide in over 2,300 adults with obesity or overweight who do not have type 2 diabetes. The study also looked at how the drug affects knee osteoarthritis and obstructive sleep apnea. Participants received either …

This study tested a simple scoring system called RISQ to help healthcare workers quickly identify which severely malnourished children are most at risk of dying. Over 14,600 children aged 6 to 59 months in Chad took part. The goal was to see if using the RISQ system could lower d…

This study compared two weight loss surgeries for people with severe obesity: SASI and SAPI. Researchers looked at costs, weight loss, and safety in 68 adults aged 18-65. The goal was to see which surgery is more affordable and effective for long-term weight control.

This study tested two mobile apps for parents of children aged 2 to 5. One app focused on nutrition, physical activity, and sleep; the other on reading. Researchers wanted to see if the apps could help parents encourage healthier habits and lower obesity risk. Over 200 parents in…

This study tested three different diet plans in 108 overweight adults with type 2 diabetes to see which best improves blood sugar control. Participants followed either standard nutrition advice, a structured meal plan with special diabetes drinks, or that same structured plan plu…

This study looked at whether a 6-month program combining exercise and healthy eating could improve the health of 36 obese office workers (BMI over 30). Participants were assigned to the program or a control group. The goal was to see changes in body fat, blood pressure, cholester…

This Phase 2 study tested a once-daily pill called RGT001-075 in 267 adults who are obese or overweight with weight-related health problems like high blood pressure or sleep apnea. The goal was to see if the drug helps with weight loss and is safe. Participants took either the dr…

This completed Phase 2 study tested different doses of CX11 tablets against a placebo in 250 overweight or obese adults. Participants took the pill once daily with meals for 36 weeks, followed by a 2-week safety check. The main goal was to see how much weight people lost and whet…

This study tested a new daily pill called DA-302168S in 250 overweight or obese adults. The pill works like a natural hormone to control appetite. Researchers measured weight loss and side effects over 16 weeks. The goal is to see if this pill is a safe and effective option for w…

This study tested a behavioral activation program given as part of a freshman orientation course at the University of Kansas. The program helps students set personal goals and engage in rewarding activities to indirectly reduce alcohol misuse, stress, binge eating, and depression…

This study tested whether adding photodynamic therapy (a light-based treatment) and vitamin D to standard deep cleaning helps people with moderate gum disease. Twenty-four adults with stage II grade B periodontitis took part. The goal was to see if the combination improves gum at…

This study tested an oral drug called LY3502970 in 72 healthy overweight and obese adults to see if it is safe and how the body processes it. Participants took the drug by mouth, and researchers monitored side effects and drug levels in the blood over up to 42 days. The goal was …

This study tested whether adding intravenous (IV) nutrition to standard oral supplements helps patients who had stomach cancer surgery recover better. 55 adults were randomly assigned to get either the combined nutrition or standard care. The main goal was to see if the combo app…

This study looked at whether eating only within a 10-hour window each day helps overweight adults aged 50 to 75 with prediabetes lose fat and improve their metabolism. 57 participants either followed the 10-hour eating plan or their usual 13-hour eating pattern, while tracking th…

This pilot study tested whether adding krill oil to standard metformin therapy improves metabolic health in women with PCOS and obesity. Fifty-four women were split into three groups: metformin alone, krill oil alone, or both together for 8 weeks. Researchers measured changes in …

This study looked at whether gastric bypass surgery or the best medical care is more effective for obese people with poorly controlled type 2 diabetes. Researchers tracked 66 participants to compare death rates, weight loss, blood sugar control, quality of life, and costs. The go…

This Phase 2 study tested an injectable drug called HRS9531 in 61 overweight or obese adults to see if it helps with weight loss over 36 weeks. Participants received either the drug or a placebo, and researchers measured changes in body weight. The goal is to find a new treatment…

This study tested a 6-month peer-led weight loss program called TOPS (Take Off Pounds Sensibly) in 116 older African American women with obesity. Participants attended dietitian-facilitated classes, while a waitlist group received the program later. The goal was to see if this co…

This study tested whether giving small weekly cash incentives (up to $300 total) for tracking what you eat and losing weight helps adults with obesity shed pounds. Over 700 participants were followed for 18 months. The goal was to see if these rewards lead to at least 5% weight l…

This study tested whether oat flakes containing β-glucan, a type of fiber, could help adolescents aged 12–18 with type 1 diabetes improve their blood sugar control, pancreatic function, and cholesterol levels. Sixty participants were randomly assigned to eat the oat flakes or a c…

This study tested whether exercising with augmented reality (AR) glasses for 12 weeks could improve metabolic health and body measurements in 20 obese adolescents aged 10-19. Half the teens used AR glasses during moderate exercise three times a week, while the other half served a…

This pilot study tested a 4-month program that combines weight loss strategies with stress management techniques for Black breast cancer survivors who have obesity and high stress. The program is based on the Diabetes Prevention Program and includes 16 sessions. Researchers measu…

This study tested four simple 'nudge' strategies to see if they could get college students to pick sugar-free drinks over sugary ones. Over 1,600 students were shown drink menus with different nudges, like showing sugar content or health warnings. The goal was to see if these gen…

This study tested a 5-day family-based treatment for adults with anorexia nervosa. The treatment, called NEW FED TR, uses insights from neurobiology to address personality traits linked to the disorder. 93 adults with anorexia and a family member or friend participated. The goal …

This study looked at whether aerobic exercise can change body composition—like body fat, muscle, water, and bone mass—in overweight and obese boys aged 8 to 12. A total of 80 boys participated, and their body measurements were taken using a special scale. The goal was to see if e…

This small study tested a new procedure that uses a special device to stitch the stomach from the inside, aiming to help people with obesity lose weight. Only 3 people took part, and the main goals were to see if the procedure is safe and leads to weight loss over 3 to 12 months.…

This study looked at whether three different low-calorie diets could improve blood sugar and body composition in 120 shift workers who are overweight and have prediabetes or type 2 diabetes. Each diet had a different amount and timing of protein. The goal was to see which approac…

This study looked at whether a 16-week strength training program can prevent or reduce late effects like muscle loss, heart disease, and diabetes in adults who had a bone marrow transplant as children. 28 survivors and a matched control group participated. The goal was to see if …

This study tested whether training older high school students as peer mentors could help younger teens become more physically active. Over 500 students from Appalachian high schools took part, comparing a peer-mentored program to a teacher-led one. The goal was to see if the ment…

This phase 2 trial tested a drug called orticumab in 77 adults with moderate-to-severe psoriasis who also had cardiometabolic risks (like obesity and high cholesterol). The goal was to see if orticumab could safely reduce skin plaques and inflammation linked to heart disease. Par…

This study tested whether eating a fermented pea-and-legume product for three weeks could improve gut health and reduce inflammation in people with metabolic syndrome. 56 adults with a large waist and at least one other risk factor (like high blood sugar or cholesterol) took part…

This study tested whether GLP-1 receptor agonists, a type of diabetes drug, can improve heart function and reduce fat around the heart in 44 obese adults with type 2 diabetes. Participants received the drug BYETTA along with metformin. Researchers used MRI scans to measure heart …

This study tested whether taking a probiotic called Hafnia alvei HA4597 can help people lose more weight and control blood sugar better after gastric bypass surgery. 49 adults with obesity and type 2 diabetes took either the probiotic or a placebo twice a day for 90 days, startin…

This study tested whether taking phytosterols (plant-based supplements) for 3 months can improve liver health, cholesterol, and insulin levels in people with nonalcoholic fatty liver disease (NAFLD). 27 participants took either phytosterol pills or a placebo. Researchers measured…

This study looked at 60 men with metabolic syndrome who also had erectile dysfunction and early signs of heart stiffness. Researchers compared three treatments: tadalafil (a common ED drug), an SGLT2 inhibitor (a diabetes drug), and a combination of both, given for three months. …

This study looked at 150 teens aged 12-17 with severe obesity to find the best time to add a weight-loss pill (phentermine) if lifestyle changes alone weren't enough. Participants first tried lifestyle therapy for 12 or 24 weeks, then those who didn't lose enough weight started t…

This study looked at whether a low-carb, high-fat ketogenic diet with fewer calories can reduce inflammation and improve blood sugar control in prediabetic obese adults aged 18 to 40. Ninety participants were split into three groups: a keto diet, a normal diet with fewer calories…

This study looked at whether eating different amounts of pecans every day for 28 days can improve cholesterol and other heart health markers in adults who are overweight or have high cholesterol. 108 participants were split into groups that ate pecans providing 6%, 13%, or 20% of…

This study looked at whether adding small amounts of cottonseed oil to the diet can improve cholesterol and other heart disease risk factors. 95 adults at increased risk for heart disease drank shakes and ate snacks with different amounts of cottonseed oil for 28 days. Researcher…

This study looked at whether a protein-enriched food mix, made from local ingredients like cereals and soy, could improve the nutritional health of older adults living in the community. Researchers also included a simple daily exercise program. The goal was to find a practical, a…

This study tested whether adding a crural repair and gastropexy to standard sleeve gastrectomy reduces acid reflux in people with severe obesity. Fifty patients were randomly assigned to either the standard surgery or the enhanced version. After one year, the group with the extra…

This study tested whether a supplement called Striatin, made from snakehead fish extract, can help severely malnourished children gain weight and reduce inflammation. Thirty children received either Striatin or a placebo alongside standard nutritional therapy. Researchers measure…

This study looked at whether adding a whey protein supplement to a reduced-calorie diet helps overweight and obese adults lose more weight and improve their metabolism. A total of 110 people aged 25-35 with a BMI of 24 or higher took part. The results will help guide better dieta…

This study tested a program called HealthyWE in 60 older adults in Camden, New Jersey, to help them manage their weight and reduce pain. The program included training on healthy eating, staying active, and mental wellness. Researchers measured changes in body mass index and pain …

This study tested a modified adjustable stomach balloon (Spatz4) in 20 adults with a BMI of 27 or higher who had struggled to lose weight with diet and exercise alone. The balloon is placed in the stomach and can be adjusted at week 16 to change its volume. The main goal was to s…

This study explores whether wearable motion sensors can improve screening for fall risk in people with chronic conditions like osteoarthritis, Parkinson's disease, COPD, and obesity. Participants will perform two standard walking tests while wearing small sensors that measure mov…

This study aims to define normal pressure thresholds during a straight leg raise maneuver in high-resolution manometry to predict acid reflux in obese patients. Researchers will analyze data from 150 obese patients undergoing preoperative assessment for bariatric surgery. The goa…

This study tested a short questionnaire called SEFI that asks children about their food intake to see if it can reliably identify those at risk for malnutrition in the hospital. Researchers compared SEFI results to standard growth measurements in 368 children aged 10-17. The goal…

This study tested a smart underwear device to see if it can detect lactose intolerance by measuring gas events after drinking lactose. 37 adults (some lactose tolerant, some intolerant) wore the device and consumed both lactose and a placebo (sucrose) on separate days. The goal w…

This study looks at how to best help childcare centers use proven methods to improve kids' diets, like hands-on activities with fruits and vegetables. About 1,850 teachers and staff from Arkansas and Louisiana will take part. The goal is to see if giving extra support to centers …

This study tests whether a 12-week lifestyle program—combining personalized nutrition advice, regular psychological support, and a walking routine—can improve sleep quality and body composition in overweight or obese women aged 60 and older. Participants will be assessed at the s…

This pilot study tests an 8-month program that coaches family childcare providers and parents together to encourage healthier eating in children aged 18 to 54 months. The intervention includes peer coaching, tailored materials, and an app to share nutrition messages, aiming to im…

This trial tests whether a single preventive nutrition and physical activity session, given just before a national holiday, can help university students with overweight or obesity avoid gaining fat during the break. The session mimics a typical public-health consultation and focu…

This study aims to develop and test a telehealth program called StEP OUT to help prevent obesity in children. It involves 40 pregnant Hispanic/Latinx women who will receive support for healthy feeding and breastfeeding. The goal is to see if the program is easy to use and accepta…

This trial tests a program called H-PACE that encourages children ages 8-11 to follow five daily goals: eat five or more servings of fruits and vegetables, limit recreational screen time to two hours, get one hour of physical activity, avoid sugary drinks, and sleep ten hours. Th…

This study tests whether using smaller or opaque bottles can help prevent rapid weight gain in newborns. Researchers will give 5 infants special bottles and track their weight and feeding habits over 4 months. The goal is to find simple ways to reduce the risk of childhood obesit…

This pilot study tests whether storytelling videos and group discussions can help parents of 2- to 4-year-olds adopt responsive feeding practices—like recognizing when a child is full—to prevent obesity. Researchers will compare three approaches: a simple handout, online videos, …

This study analyzes health records from over 2 million adults across five continents to see if GLP-1 receptor agonists (like semaglutide and liraglutide) can lower the risk of developing Alzheimer's disease. It focuses on people aged 40 and older with type 2 diabetes or obesity, …

This study tests whether an 8-week program combining gentle yoga and tai chi with acceptance-based techniques can lower the risk of developing anorexia nervosa in female college students who already have elevated body shape concerns. Participants are randomly assigned to the mind…

This study tests a summer garden program called 'Summer Harvest Adventure' for children aged 8 to 11 from low-resource communities. The program teaches nutrition and healthy habits through gardening and cooking activities. Researchers will measure changes in fruit and vegetable i…

This completed study tested a 24-month program that combined face-to-face counseling with digital tools to help families prevent and manage type 2 diabetes and high blood pressure. Over 1,200 adults and their children from Albania, Bulgaria, Greece, and Spain took part. The progr…

This study tested whether a single infusion of zoledronic acid can prevent bone and muscle loss in adults aged 35 and older who are undergoing bariatric surgery. Fifty-nine participants were randomly assigned to receive either the drug or a placebo. The main goal was to measure c…

This study looked at whether a Mediterranean diet, weight loss, or both could lower colorectal cancer risk in 180 obese African Americans aged 45-75. Participants followed one of four plans for six months, and researchers measured changes in bile acids, gut bacteria, and cell act…

This study tested whether offering free summer day camps with physical activity, enrichment, and meals could reduce unhealthy weight gain in 651 first- to third-graders from low-income households. The camps removed cost barriers that often lead to sedentary time and poor diet dur…

This study tested a virtual program called FED-F that helps people with anorexia nervosa face their fears about food, weight gain, body sensations, and social situations. The goal is to prevent relapse after intensive treatment. The study included 70 adults who had recently compl…

This pilot study tested whether adding health literacy lessons to an obesity prevention program helps teenagers eat healthier and be more active. 36 adolescents aged 13-16 took part. The program taught them how to find, understand, and use health information to make better choice…

This study tests whether training the muscles you use to breathe can improve how long obese breast cancer survivors can exercise. Researchers will compare breathing exercises plus aerobic exercise to aerobic exercise alone in 78 women who finished treatment. The goal is to see if…

This study tests whether brief, one-minute exercise breaks—called 'exercise snacks'—can improve fitness and health in adults with obesity. Eighty inactive participants aged 35-64 will use a phone app to do personalized movement breaks throughout the day for 12 weeks. The goal is …

This study looks at whether aggressive weight loss using semaglutide can improve symptoms in people with a specific type of heart failure linked to obesity. About 81 participants with a BMI of 30 or higher and heart failure with preserved ejection fraction will receive either sem…

This study is testing a new probiotic called CLB101TM in healthy but overweight adults who have digestive issues like bloating or stomach pain. The probiotic is designed to produce a natural substance called butyrate, which may help strengthen the gut lining and support immune he…

This study tested whether online occupational therapy-based parent coaching could improve feeding problems in children aged 3-6 who were born prematurely. 39 mothers participated, with some receiving coaching and others not. The coaching aimed to teach mothers better feeding stra…

This study looked at whether quercetin, a natural substance found in foods like apples and onions, can change how the body absorbs sugar. Researchers gave 24 obese adults (some with type 2 diabetes) either quercetin or a placebo during a sugar-drink test. They measured blood suga…

This trial tests whether a continuous infusion of the local anesthetic ropivacaine, delivered through small catheters placed near the breastbone, can improve recovery after cardiac surgery. The study focuses on patients at higher risk of respiratory complications, such as older a…

This study tests whether the medication lisdexamfetamine (Vyvanse) can help people who experience loss-of-control eating after bariatric surgery and didn't improve with earlier treatments. About 60 adults who had gastric bypass or sleeve gastrectomy will receive either the drug o…

This pilot study tests whether a ketone drink can help people with anorexia or bulimia by reducing the drive to binge or restrict food. Forty participants will take the drink twice daily for two weeks, and researchers will measure changes in eating behaviors, mood, and brain acti…

This trial tests whether a special liquid nutrition formula, enriched with arginine, omega-3 fatty acids, and nucleotides, can reduce the frequency and severity of mouth sores (mucositis) in patients with head and neck or esophageal cancer undergoing chemoradiotherapy. Participan…

This study explores whether an AI-powered chatbot can deliver personalized sleep coaching to Black/African American adults aged 18-25 who have poor sleep and at least one cardiometabolic risk factor. The chatbot uses principles of cognitive-behavioral therapy for insomnia (CBT-I)…

This trial investigates whether a 20-minute virtual reality nature scene or the Benson Relaxation Technique can lower anxiety and increase happiness in adults who have recently had bariatric surgery. Participants are randomly assigned to one of two groups or a control group, and …

This study tested a self-help tool called EMBER to see if it helps veterans with obesity engage in VA weight management programs. 470 veterans were randomly assigned to receive EMBER or just a list of programs. Researchers tracked whether participants used weight management servi…

This trial tests a digital, gamified program called FlexED designed to help young women aged 15-25 with early signs of eating disorders. Participants complete eight 20-30 minute sessions on their phone, following an avatar through a story and interactive exercises based on Accept…

This study tests whether liquid or pill acetaminophen works better for pain after gastric bypass or sleeve gastrectomy. Surgery changes how the stomach absorbs medication, so the form of the drug could affect pain relief. Adults who had one of these procedures will receive either…

This study looks at whether giving a nerve block (TAP block) early during laparoscopic sleeve gastrectomy reduces pain more than giving it later. About 200 adults having this weight-loss surgery will receive the same numbing medicine, but at different times. Researchers will comp…

This trial tests whether a type of talking therapy called CBT-AR can help young people aged 12 to 25 with avoidant/restrictive food intake disorder (ARFID). ARFID is an eating disorder where people avoid certain foods or eat very little, not because of body image concerns but due…

This study tested whether adding dog-assisted therapy to usual care helps teens aged 12-18 with mental health issues like anxiety, depression, and emotional dysregulation. 70 teens in a day hospital were randomly assigned to either get dog therapy plus usual care or usual care al…

This completed trial tested whether virtual reality therapy can help people with anorexia or bulimia. 96 participants either received virtual reality sessions plus usual care, or usual care alone. In the VR sessions, they created an avatar representing their 'eating disorder voic…

This small, completed study tested whether a gentle brain stimulation technique called tDCS, combined with computer-based cognitive training, is safe and tolerable for adults with anorexia or atypical anorexia. One participant received either real or fake stimulation over 10 sess…

This study tested whether a daily probiotic capsule containing two bacterial strains could reduce gastrointestinal symptoms like bloating, gas, and cramps in adults with lactose intolerance and methanogenic intestinal overgrowth. Twenty-two adults took either the probiotic or a p…

This study tested whether taking 1,000 mg of glycine daily for six months could improve memory and thinking in older adults. Fifty-nine participants took the supplement, and researchers measured changes in a brain health marker and cognitive test scores. The goal was to see if th…

This study tested whether a 10-session Dialectical Behavior Therapy (DBT) skills program could reduce rumination (repetitive negative thinking) and cognitive avoidance (avoiding difficult thoughts) in middle-school teachers. Thirty-four female teachers in Iran took part, with hal…

This study tested whether adding a resveratrol supplement to a low-calorie diet helps postmenopausal women with obesity and knee osteoarthritis. Ninety-seven women took either the diet alone or the diet plus 150 mg of resveratrol daily for 10 days. Researchers measured pain, func…

This study tested three short, one-time digital sessions (called Project YES) designed to help teens and young adults ages 13-25 who have depression, anxiety, or eating disorder symptoms. Participants completed questionnaires before the session, right after, and again 3 months la…

This study tested whether a 12-week home-based circuit training program could improve blood vessel function and metabolism in adults with obesity. Twenty-nine participants were randomly assigned to either the exercise group or a control group that continued their usual activities…

This study tested a program called Family Connections for caregivers of people with both an eating disorder and a personality disorder. The goal was to see if the program could reduce stress and conflict at home. 124 Spanish caregivers took part, and researchers measured things l…

This study tested whether silkworm pupa tablets can improve nutrition and reduce frailty in people who had surgery for stomach, colorectal, esophageal, or pancreatic cancer. 120 participants took the tablets for 3 months. Researchers measured weight, frailty, muscle mass, and qua…

This small pilot study tested whether a technique called bilateral stimulation (side-to-side tapping) could help people with eating disorders feel less anxious after eating foods they normally avoid. Eight adults in outpatient treatment either received standard care alone or stan…

This study tested whether repetitive transcranial magnetic stimulation (rTMS) can help overweight and obese adults lose weight and reduce food cravings. Fifty participants received either real rTMS, fake rTMS, or no treatment over 5 weeks. The goal was to see if stimulating a spe…

This study tested whether a dietary supplement called NatureU Burn, made from African mango seed extract and inulin, can increase feelings of fullness after a sugary drink. Fourteen healthy adults took either glucose alone or glucose plus the supplement, then rated their fullness…

This study looked at whether taking Korean ginseng extract daily for eight weeks could reduce fatigue and improve exercise performance in healthy adults aged 20 to 50. Sixty participants were randomly assigned to receive either the ginseng extract or a placebo. The researchers me…

This study tested whether using a lower amount of fresh gas during anesthesia (low-flow) could reduce lung collapse (atelectasis) after laparoscopic weight-loss surgery. Sixty adults were randomly assigned to receive either low-flow or normal-flow anesthesia. The researchers meas…

This study looked at whether taking soluble dietary fiber supplements can improve sperm quality in men with obesity. 74 men took either fiber or a placebo for a period. The goal was to see if fiber could help with sperm movement, shape, and count, which are often poor in men with…

This study tested a new combination of two talk therapies for adults with eating disorders who are not underweight. Twenty participants were randomly assigned to either standard cognitive behavioral therapy (CBT-E) or a mix of CBT and metacognitive interpersonal therapy (CBT-F+MI…

This study tested a dietary supplement called WM Formula in 20 adults with high body fat. The supplement aims to increase GLP-1, a hormone that helps control blood sugar and appetite. Participants took the supplement or a placebo and had blood tests over several hours. The study …

This study looked at whether changing how often women eat (meal frequency) can improve their confidence and reduce stress while dieting. It involved 72 women aged 25-55 who had a history of losing and regaining weight (weight cycling) and were overweight or obese. The goal was to…

This study tested whether the herb Salacia chinensis, known to slow sugar absorption, can help control appetite and blood sugar in overweight or obese adults. Fifty-one participants took either a low or high dose of the herb or a placebo with a meal. Researchers measured appetite…

This study tested whether listening to a 10-minute affirmation podcast daily for 21 days could reduce fear of childbirth and repetitive negative thoughts in pregnant women. 120 women in Istanbul took part, with half listening to the podcast and half receiving no intervention. The…

This pilot study tested whether a home-based, supervised exercise program is acceptable and safe for 36 women with anorexia nervosa. Participants were asked to complete 8 weekly exercise sessions at home. The study measured how many people joined and finished the program, their s…

This study looked at 290 people having laparoscopic sleeve gastrectomy (a weight-loss surgery) to see which method of reinforcing the staple line works better to prevent leaks. One method uses titanium clips, the other uses suturing and omentopexy (tacking the omentum over the st…

This study tested whether a diet packed with fiber, but lower in calories and sugar, helps control blood sugar after meals and keeps people feeling full. Twenty-four overweight or obese adults ate either the high-fiber diet or a typical Western diet for a short period. Researcher…

This study tested a new video laryngeal mask airway (SaCoVLM™) in 57 morbidly obese patients undergoing bariatric surgery. The device helped doctors place a breathing tube on the first try in most cases. The goal was to see if it is safe and effective for this group of patients.…

This study developed and tested a mobile app with coaching and a social network for adults with anorexia nervosa who recently left intensive treatment. The goal was to see if the app could help reduce eating disorder symptoms compared to usual care. 90 women participated, and the…

This study tested whether following a very low calorie diet before bariatric surgery helps patients lose more weight and feel more satisfied. 85 adults who were eligible for surgery took part. Researchers compared the very low calorie diet to standard dietary advice.

This study tested a self-guided smartphone program for women with disordered eating. Twenty women used their phones to track eating habits for two weeks, then received two personalized treatment modules. Researchers checked if the program was easy to use and if it helped reduce s…

This study tested two types of balance training—whole body vibration therapy and balance board exercises—in 44 obese adults with mild knee osteoarthritis. Over eight weeks, researchers measured pain, mobility, and quality of life to see which approach worked better. The goal was …

This study tested a weight management program called MOVE!+UP, designed specifically for veterans with PTSD who are overweight or obese. The program adds extra support to standard PTSD care to help overcome barriers like stress and unhealthy habits. Researchers compared it to the…

This study tested whether repeated positive mirror exposure can help female university students with disordered eating feel better about their bodies and emotions. Seventy-five participants took part in guided sessions where they observed themselves in a mirror and focused on neu…

This early-stage study tested a new injection called HRS-4729 in 102 healthy adults who were overweight or obese. The main goal was to check if the drug is safe and how the body processes it. Participants received either the drug or a placebo, and researchers monitored side effec…

This study tested a 6-week group program combining nutrition education with psychological sessions based on Well-Being Therapy in 50 adults with obesity. The goal was to see if improving mental health could lead to healthier, more sustainable eating and weight loss. Participants …

This study looked at whether standing on a vibrating platform while doing foot exercises could improve ankle strength, balance, and body awareness in overweight and obese young adults. Twenty-six people took part in supervised sessions three times a week for eight weeks. The resu…

This study tested whether an 8-week mindfulness app is practical and liked by people with anorexia or bulimia. 32 adults who were already in eating disorder treatment used the app at home. The goal was to see if they would complete the modules and find them helpful, not to cure t…

This early-stage study tests a single dose of the experimental drug PF-08653944 in 54 overweight or obese adults. Researchers want to see how the drug is absorbed when injected into the abdomen, thigh, or upper arm. The study also monitors safety through blood tests and vital sig…

This study looked at how being in different temperatures (from about 61°F to 88°F) affects how many calories healthy adults burn. Researchers also checked for brown fat activity, a type of fat that burns energy to keep you warm. 104 healthy men and women stayed in a hospital unit…

This trial explores whether a blood test measuring reticulocyte hemoglobin content (RET-He) can predict how well cancer patients with anemia will respond to intravenous iron treatment. The study involves adults with solid tumors who have functional iron deficiency. By checking RE…

This completed study looked at risk factors for diabetes and heart disease in 146 healthy African, African-American, and white women who were federal employees or contractors. Researchers compared things like triglyceride levels and insulin resistance to see if the best screening…

This study looks at whether a specific blood protein, apolipoprotein, can predict how much weight people lose after sleeve gastrectomy surgery for severe obesity. Researchers will measure protein levels before surgery and track weight loss for 8 months in 110 adults. The goal is …

This study looks at how type 2 diabetes affects young people aged 12 to 25. Researchers want to see if giving the pancreas a 2-week rest with insulin shots can improve its ability to make insulin. Participants take metformin, follow a diet, and some also get insulin. The study al…

This study aims to understand why some people gain or lose weight more easily than others. Researchers will measure how the body's energy use changes during overeating and dieting in 83 healthy adults. Participants will stay in the hospital for 10 weeks, undergoing tests like met…

This study analyzed health records of over 200,000 adults with obesity and type 2 diabetes to see if taking GLP-1 drugs (like Ozempic) before a cancer diagnosis is linked to better survival and fewer complications after cancer. The researchers compared GLP-1 users to those on oth…

This study looked at whether adding folic acid and vitamin B12 to locally made cereals can improve the nutrition, thinking skills, and mood of teenage girls in rural Ethiopia. About 472 girls aged 13-19 took part. The goal was to see if small-scale food fortification can help pre…

This study uses advanced MRI scans to see if bariatric surgery (weight-loss surgery) can improve the health of the pancreas in people with severe obesity. Researchers will scan the pancreas before surgery and again six months after, measuring fat content, tissue stiffness, and ot…

This study looks at how weight loss surgery (gastric sleeve) affects exercise ability in people with or at risk for heart failure with preserved ejection fraction (HFpEF). Researchers will measure oxygen use during exercise before and 12 months after surgery. The goal is to under…

This study looked at nearly 5000 adults having planned abdominal surgery. Researchers checked their nutrition before the operation and tracked infections and recovery. The goal was to see if better nutrition before surgery leads to fewer complications.

This clinical trial is testing a medical device that has not been approved or cleared by the U.S. FDA. The specific purpose, who can join, and how the device works are not publicly available. Because key details are withheld, it is not possible to describe the expected benefits o…

This study looked at how often thiamine (vitamin B1) deficiency occurs in hospitalized veterans who do not abuse alcohol. Thiamine deficiency can cause symptoms like fatigue, confusion, and weakness, and may be more common in veterans due to food insecurity and chronic illness. R…

This observational study looks at whether muscle loss, measured on routine CT scans, is linked to 28-day survival in adults with cancer who are admitted to the intensive care unit (ICU). Researchers will compare muscle quality and nutritional scores between patients who survive a…

This study aims to understand how ultra-processed foods affect energy metabolism compared to unprocessed foods. Healthy adults aged 18-60 will stay at a research center for four weeks, eating different diets each week. Researchers will measure how much they eat, their metabolic r…

This completed pilot study in Yomitan Village, Okinawa tested three simple, low-cost approaches to reduce stress and encourage healthy habits in 45 adults with overweight or pre-metabolic syndrome. Participants were randomly assigned to receive health leaflets, wear functional cl…

This study looked at whether cycling in a cool room versus a warm room changes how much fat overweight women lose. Thirty women rode a stationary bike three times a week for three months. Researchers measured body fat, waist size, and blood markers to see if temperature makes a d…

This study looks at whether people with type 2 diabetes who eat more dairy products (like milk, cheese, and yogurt) during an intensive lifestyle program have better blood sugar control and weight maintenance. Researchers will track changes in A1C, weight, and cholesterol in abou…

This study will test whether putting warning labels on social media posts about ultra-processed foods helps teens and young adults understand what they are eating and whether they would buy those products. About 1,000 people aged 13-29 in the U.S. will view Instagram posts with o…

This trial investigates how replacing animal proteins with plant proteins in the diet influences metabolism. Adults with early signs of metabolic syndrome (like high triglycerides or slightly elevated blood pressure) will follow a controlled diet for four weeks, either predominan…

This early-stage study tests how two different injection versions of the experimental drug AMG 133 are absorbed by the body in 349 adults with overweight or obesity. Participants receive a single dose, and researchers measure drug levels and safety. The goal is not to treat obesi…

This trial investigates how different ways of creating an energy deficit affect appetite and food intake in adolescents with obesity. Participants will experience three conditions: exercise combined with dietary restriction, dietary restriction alone, and a rest control. Research…

This completed Phase 1 study looked at how vitamin E is absorbed and used in the bodies of normal-weight and obese women, and whether vitamin C helps. Fifty women aged 18 to 40 took part, including some with type 2 diabetes. Researchers gave different doses of vitamin E (by mouth…

This study explores whether compounds in cannabis, like THC and CBD, can reduce inflammation and improve how the body responds to insulin. Researchers will measure blood markers of inflammation and insulin sensitivity in people across the weight spectrum, both after a single use …

This study is testing whether a specific gene variant (MC4R rs17782313) and metabolic health status influence how men with obesity respond to a 12-week exercise and diet program. Forty men aged 18 to 59 with obesity will be classified as having metabolically healthy or unhealthy …

This study investigates how obesity treatments, such as bariatric surgery or medication, influence food purchasing habits in daily life. Researchers will collect digital receipts from loyalty cards and have participants fill out questionnaires over several years. By analyzing the…

This study explores how weight-loss surgery changes the body's protein needs and whether fast-absorbing milk proteins can help preserve muscle mass and strength. Researchers will measure nitrogen balance and muscle function in 25 adults with severe obesity before and after gastri…

This study looks at how the body's energy use changes during weight loss and regain in adolescents with obesity. Researchers will track resting and exercise energy expenditure, body composition, and food preferences in 40 teens aged 12-16 over a 12-month behavioral program. The g…

This study looks at whether a single 30-minute cycling session can alter how adolescents with obesity experience hunger and food reward after a fixed meal. Researchers will measure appetite feelings, food preferences, and how much they eat at a later dinner. The goal is to unders…

This trial compares how burning calories through exercise versus cutting calories through diet affects appetite and food intake in adolescents with obesity. Participants (aged 12-16) will undergo both conditions—an exercise session and a dietary restriction—and their hunger, food…

This study looked at how people with and without non-alcoholic fatty liver disease (NAFLD) process food. Researchers monitored 53 adults over two days, measuring metabolism, blood, and urine after meals. The goal was to find differences that might explain why fat builds up in the…

This study reviews the feeding skills of 100 infants discharged from a neonatal intensive care unit (NICU). Researchers want to know if an infant's ability to eat a full amount by mouth means they have fully developed feeding skills. They use a special tool called the SMART Tool …

This study looks at whether doing exercise 30 minutes versus 180 minutes before lunch changes how much adolescents with obesity eat at that meal. Participants, aged 12-16, will cycle at a moderate intensity at one of those times, then eat a buffet lunch where their intake is meas…

This study looks at what makes some women naturally lean without dieting or eating disorders. Researchers will compare eating habits, physical activity, body composition, and appetite responses in three groups: constitutionally lean women, normal-weight women, and women with anor…

This study looks at how a 12-week weight loss program—combining nutrition advice, exercise, and psychological support—changes the way teenagers with obesity burn energy. Researchers want to understand the separate roles of metabolic and mechanical load on energy expenditure durin…

This study is testing whether following a Mediterranean-style diet based on U.S. dietary guidelines improves heart health more when combined with weight loss. Researchers will provide all meals for 70 adults with obesity or excess body fat for eight weeks. Participants will be sp…

This study tested whether taking tadalafil (Cialis) daily for 12 weeks can change how fat tissue works in obese adults. Researchers used MRI scans and fat samples to measure fat metabolism and gene activity. The goal was to understand if the drug could make fat behave more like c…

This study tested whether taking a synbiotic (a mix of probiotics and prebiotics) for 30 days could improve gut bacteria, weight, and heart health in 47 healthy adults aged 18-60. Participants were randomly assigned to receive the supplement or a placebo. The goal was to gather i…

This study investigates whether sex and obesity influence how blood vessels respond to low oxygen levels, a key factor in sleep apnea. Researchers will compare healthy-weight and obese men and women to see if differences in vessel constriction and dilation help explain why women …

This study investigates how the amount of sugar or fat in a person's diet, along with how many meals they eat each day, influences the body's fat production, blood fat levels, and liver fat storage. Overweight adults aged 20–65 will follow different meal patterns—ranging from two…

This study compares two ways of using a breathing machine during weight-loss surgery in 34 obese patients. One method controls the flow of air, the other controls the volume. Researchers want to see which method keeps the lungs and heart more stable during surgery. Participants w…

This pilot study tests a smart changing pad designed to monitor infants after they leave the hospital or NICU. The pad measures weight, tracks diaper changes, feeding sessions, and sleep, and syncs data to a mobile app and a secure provider dashboard. Researchers want to see if c…

This study investigates how specific fat molecules called diacylglycerols and sphingolipids inside muscle cells influence insulin resistance. Researchers will measure these lipids in different parts of muscle cells before and after weight loss or exercise in people with obesity, …

This study looks at how two different ways of managing pain after laparoscopic sleeve gastrectomy affect lung function. One method uses an epidural catheter to deliver numbing medicine near the spine, while the other uses pain medicine given through an IV. Researchers measure bre…

This study looks at how common dissociative tendencies are in adults with obesity who are seeking medical or surgical help for the first time. Participants fill out questionnaires that measure dissociation, eating behaviors, and other related factors. The goal is to better unders…

This study investigates whether short-term diet changes cause inflammation in the hypothalamus, a brain region that controls body weight. Overweight adults aged 20-40 eat specially prepared meals for 14 days, alternating between high- and low-calorie periods. Researchers use MRI …

This study looks at whether two popular weight-loss medications, semaglutide and tirzepatide, can improve early signs of liver damage in people with overweight or obesity. Researchers measured changes in liver health markers after at least 12 weeks of treatment in 154 adults. The…

This study looked at whether placing patients in a specific position (head up, feet down) before starting laparoscopic weight-loss surgery could reduce pressure on the brain. Researchers measured the optic nerve sheath diameter, an indicator of brain pressure, in 90 patients. The…

This study aims to adapt a sleep-improvement program for African American adults who are overweight and sleep less than 6 hours per night. Researchers will test if the program is practical and satisfying for participants. The goal is to reduce health disparities linked to poor sl…

This study tests a 12-week program that teaches parents how to use positive, supportive feeding practices to help their children eat better and grow healthily. It includes 36 parents and their children aged 5-11 who are at risk for obesity. The program focuses on giving parents t…

This study looks at how time restricted eating (eating only during a 6-hour window each day) affects metabolism and immune function in healthy women aged 18-50 with different body sizes. Participants will stay in the clinic for 5 days, follow the eating schedule for 3 days, and u…

This study examines why some people with obesity find it hard to lose weight, while lean individuals struggle to gain weight. Researchers measure how the body uses energy during fasting and after a special low-protein meal. By comparing these responses, they aim to identify diffe…

This study tests whether a device called the oxygen reserve index (ORi) can warn doctors earlier than standard pulse oximetry when an older patient's oxygen level starts to drop during surgery. Researchers are comparing obese and non-obese patients aged 65 and older to see if ORi…

This study looks at whether the neck-to-waist ratio can help identify patients with high blood pressure and a specific type of heart attack. Researchers measured body shapes of 238 adults arriving at the emergency room with chest pain. The goal is to see if simple body measuremen…

This completed pilot study examined how fat tissue dysfunction contributes to type 2 diabetes risk in overweight men from South Asian, Black African/Caribbean, and White European backgrounds. Researchers used MRI scans and blood tests to measure fat distribution, inflammation, an…

This completed pilot study tested a 6-week web-based program called Mind Your Heart in 37 adults who were university employees. The program combined DASH diet education with mindful eating training to improve eating habits and health measures like blood pressure and cholesterol. …

This study used ultrasound to measure the optic nerve sheath (the lining around the eye nerve) in 56 adults having laparoscopic bariatric surgery. The goal was to see how brain pressure changes during surgery due to gas inflation and body positioning. No drug or treatment was tes…

This study looked at how different types of anesthesia affect thinking and memory after surgery in 90 obese patients. Some received sevoflurane gas at low or normal flow, others received intravenous anesthesia. Researchers tested their mental function before surgery, 30 minutes a…

This Stanford study tested whether showing health or climate labels on grocery products, along with swap suggestions, helps people pick healthier and lower-carbon foods. Over 1,200 adults completed online shopping tasks and surveys. The goal was to see if simple labels can guide …

This study looked at whether replacing non-dairy foods with two servings a day of full-fat or low-fat fermented dairy (like yogurt and cheese) could improve insulin sensitivity and other heart health markers. 110 overweight adults with high triglycerides took part. The goal was t…

This study analyzed health records of over 118,000 adults with obesity, type 2 diabetes, and related heart, kidney, and liver conditions. Researchers compared people who added a second type of diabetes drug (GLP-1 or SGLT2) early to those who did not. The goal was to see if early…

This study looks at how upper body versus lower body combined strength and endurance training affects two key proteins in overweight and obese men: myostatin, which regulates muscle growth, and hormone-sensitive lipase, which helps break down fat. Thirty-six men were split into t…

This study looked at whether the ratio of urea to creatinine in urine can help identify malnutrition in intensive care patients with brain injury. Malnutrition is common in the ICU and raises the risk of infections. Researchers measured this ratio in 309 adults and tracked six ty…

This study examined how being obese (BMI over 30) affects hospital outcomes after coronary artery bypass grafting (CABG) in 500 patients with chronic ischemic heart disease. Researchers tracked death rates, neurological injury, kidney injury, breathing machine time, and need for …

This study looked at 40 adults who had sleeve gastrectomy surgery for obesity. Researchers measured blood levels of fractalkine, a protein involved in inflammation, before and three months after surgery. The goal was to see how fractalkine levels change and whether those changes …

This study looks at whether gastric bypass surgery can protect the kidneys of people who are severely obese and have chronic kidney disease. Researchers measured kidney function before and one year after surgery in 14 patients. The goal is to see if the surgery improves the balan…

This study explored how Ramadan intermittent fasting changes gut bacteria and intestinal barrier function in healthy adults. Researchers followed 79 participants from Italy and Lebanon before, during, and after the fasting month. They collected blood and stool samples to measure …

This study tested whether raising ketone levels—either through a ketogenic diet or a ketone supplement—can improve markers of obesity-related disease risk in overweight adults. Sixty-nine participants followed either a keto diet or took a ketone drink for four weeks. Researchers …

This study looked at health records from over 5,000 adults to see if having an H. pylori stomach infection is linked to metabolic syndrome—a cluster of conditions like high blood sugar, high blood pressure, and excess belly fat. Researchers compared people with and without the in…

This study looked at 255 people with severe obesity who had weight-loss surgery. Researchers wanted to see if losing weight could improve liver scarring (fibrosis) by measuring certain blood tests before and one year after surgery. The goal was to understand how weight loss affec…

This study examined the link between obesity and iron deficiency anemia in 165 nonpregnant Indonesian women aged 19-29. Participants took daily iron-folic acid supplements for 90 days. Researchers compared iron levels between overweight/obese and normal-weight women to see if wei…

This study followed 53 adults with overweight or obesity who were already receiving standard lifestyle-based weight loss care at a clinic. Researchers measured changes in body weight, fat mass, blood sugar, cholesterol, and other health markers before and after weight loss. The g…

This study followed 75 malnourished patients after they left the hospital to see what kind of care they received and how their nutrition changed. Researchers also interviewed some patients and caregivers to learn about their understanding of malnutrition. The goal is to improve s…

This study looked at 60 obese adults scheduled for weight-loss surgery. Doctors used an ultrasound before surgery to measure how much food or liquid was still in the stomach, even after fasting. The goal was to see if a higher body mass index (BMI) or longer fasting time was link…

This study looks at why young women with anorexia nervosa lose bone density. Researchers will compare 160 patients with 160 healthy women to measure bone mass and check hormones and other markers. The goal is to find the key factors behind bone loss, which could lead to better tr…

This study looked at how the upper part of the gut (foregut) senses nutrients and controls metabolism in 27 lean and obese adults. Researchers measured hormone and sugar levels after feeding through a tube to understand if faulty gut signals contribute to obesity. The goal was to…

This study collects and stores medical data from adults who had robotic bariatric surgery between 2018 and 2019. The goal is to build a database that helps doctors understand how well this type of surgery works for weight loss and related health issues. By analyzing real-world ou…

This pilot study investigates how common low energy availability, iron deficiency, and low vitamin D levels are among Black collegiate athletes. Participants who are found to have low iron or vitamin D will receive daily supplements for 12 weeks. The goal is to better understand …

This study looked at 90 adults who had bariatric surgery to see if changing the variety of foods they ate affected their food cravings, calorie intake, and weight loss over 12 months. Researchers tracked participants' diets to understand patterns that might help improve long-term…

This study looked at how often people eat and whether it affects weight loss. Researchers followed 30 overweight adults aged 18 to 65. They tracked eating habits, calories, and weight to better understand the link between meal timing and losing weight.

This study looked at whether eating foods with fewer calories per bite (low energy density) helps people lose weight. Sixty adults with overweight or obesity followed a 12-week lifestyle program. Researchers tracked what they ate, how full they felt, and weight changes to find th…

This study looked at how three different types of dietary advice affect what families eat and their overall health. It involved 45 families with an overweight parent and a child aged 6-12 who was at a healthy weight. Researchers measured changes in diet, body measurements, and pa…

This study looked at 53 obese patients having laparoscopic sleeve gastrectomy (weight-loss surgery) to compare two ways of helping them breathe during the operation. One group received standard ventilation support, while the other got a stronger support with higher pressure and e…

This study looked at how certain gut hormones change after eating a standard meal in 80 adults aged 40-60 with different body weights. Researchers measured hormones like GLP-1 and GIP, which help control appetite and blood sugar. The goal was to understand how these hormone respo…

This study looked at how obesity affects the way children's bodies process common acid reflux medications like lansoprazole and pantoprazole. Researchers gave a single dose of these drugs to 76 children aged 6-21, both with and without obesity, and measured how long the drugs sta…

This study looked at how levels of ghrelin, a hormone that controls hunger, change after eating a standardized meal in 80 adults aged 40-60 with different body weights. Participants drank a nutritional supplement, and their blood was tested over several hours. The goal was to und…

This study looked at 88 women newly diagnosed with primary hypothyroidism (underactive thyroid) to see if taking levothyroxine to normalize thyroid hormones also improves metabolic health. Researchers measured special proteins called adipokines, which are linked to fat tissue and…

This study looked at whether obesity increases the body's production of oxalate, a substance that can lead to kidney stones. 58 adults without a history of kidney stones ate a special low-oxalate diet for 4 days and provided urine samples. Researchers measured oxalate levels to s…

This study used MRI to examine how the brain and gut communicate after eating different types of drinks in people with obesity and healthy weight. Researchers gave participants a high-fat drink or a carbohydrate drink and scanned their brains and stomachs. The goal was to develop…

This completed study followed 687 people who had bariatric surgery (gastric bypass or sleeve gastrectomy) in Norwegian public hospitals between 2010 and 2015. Researchers aimed to see how long weight loss lasts and whether related health problems like diabetes, high blood pressur…

This study looked at 30 undernourished teens with anorexia, aged 11 to 17, to see how taking oral phosphorus supplements for 6 months changes a hormone called FGF23, which helps control phosphate and vitamin D levels. The goal was to understand the link between phosphorus intake …

This completed study from Purdue University looked at whether GLP-1 receptor agonists (like Ozempic or Wegovy) change how people taste, smell, and crave food. Researchers compared 90 adults with obesity who were either not taking the drug, or had been taking it for about 1 month …

This study measured how often adults with inflammatory bowel disease (Crohn's disease or ulcerative colitis) show signs of eating disorders, including avoidant/restrictive food intake disorder (ARFID). Researchers used questionnaires to assess eating habits and nutritional status…

This study looked at whether a nutrition training program for family child care home providers could improve the food they serve to young children. 72 providers in Oklahoma took part, with half getting the nutrition program and half a comparison on environmental health. Researche…

This study looked at whether exercising right before a meal changes how much teenagers eat. Researchers tested 54 teens with normal weight or obesity, having them exercise at different times or rest. They measured appetite, taste and smell responses, and daily habits like sleep a…

This study tested a technique to help doctors insert a breathing tube in very obese patients having weight-loss surgery. The method uses a laryngeal mask airway as a temporary helper to keep oxygen flowing while the doctor prepares for the main tube. Thirty-six patients took part…

This study looked at whether saliva can be used to measure endocannabinoids—natural chemicals linked to appetite and weight—instead of taking blood. Researchers compared 12 obese and 12 normal-weight adults after fasting. The goal was to see if saliva levels differ between the gr…

This study looked at whether vitamin D levels in the blood affect the chance of a successful pregnancy after in vitro fertilization (IVF). Researchers followed 688 women aged 21-40 undergoing their first IVF cycle. The goal was to see if women with higher vitamin D levels had hig…

This completed study looked at how 26 premature infants and babies with Pierre Robin sequence suck. The goal was to better understand their feeding challenges so doctors and families can offer better support. Researchers used a special device to measure sucking patterns, aiming t…

This study measured levels of a hormone called pregnenolone and related compounds in the blood of 25 men—some with obesity and some at a healthy weight. Researchers wanted to see if a breakdown in the body's natural feedback loop might lead to overactivity of the endocannabinoid …

This study looked at how the body's natural endocannabinoids (similar to cannabis compounds) interact with the stress hormone cortisol in people with Cushing's syndrome, a condition of high cortisol. Researchers measured blood levels of these compounds in 40 participants, includi…

This study looked at whether eating maize (corn) with extra zinc can improve gut health and nutrition in mothers and young children in Guatemala. 60 people took part. Researchers measured zinc levels, inflammation, and gut bacteria to see if the special corn made a difference.

This study tested whether using a special breath test (indirect calorimetry) can help doctors give the right amount of nutrition to critically ill patients with obesity who are on breathing machines. The study involved 60 adults from intensive care units in Australia and New Zeal…

This completed Phase 1 study looked at how orforglipron, an experimental drug, changes the way the body processes several common medications (digoxin, simvastatin, rosuvastatin, acetaminophen, and midazolam) in 50 healthy overweight or obese adults. The goal was to measure drug l…

This completed Phase 1 study in 34 adults with overweight or obesity examined whether CagriSema (a combination of cagrilintide and semaglutide) changes how the body processes atorvastatin (a cholesterol drug) and warfarin (a blood thinner). Participants took single doses of atorv…

This study looked at whether vitamin D levels affect how well broken bones heal in young adults aged 18 to 25. Researchers measured vitamin D at the time of injury and tracked healing for up to a year. The goal was to understand if low vitamin D is linked to slower healing or com…

This study looked at how lifestyle factors like diet and health habits affect a couple's ability to conceive. Researchers followed 266 couples planning their first pregnancy, tracking how long it took to get pregnant and any early pregnancy losses. The goal was to better understa…

This study tested a special gluten-free food guide designed to help children and teens (ages 5-18) with newly diagnosed celiac disease eat a healthier diet. Forty participants received either standard care or the new guide. Researchers measured diet quality and how well they foll…

This study tested whether adding omentopexy — stitching the omentum to the stomach — during sleeve gastrectomy changes stomach shape and emptying. Thirty-six adults having weight-loss surgery were randomly assigned to get the extra stitch or not. Researchers measured stomach angl…

This completed study looked at 126 people with different fat distribution patterns—including those with lipodystrophy (abnormal fat loss or distribution), obesity, and normal weight—to understand how fat tissue relates to insulin resistance and immune signals. Researchers measure…

This study looked at how eating a high-fat diet for 5 days affects inflammation in older adults (ages 50-79) with normal weight or obesity. Researchers measured blood markers and gut bacteria to see if a high-fat diet causes more inflammation than a low-fat diet. The goal was to …

This study tested whether a protein from amaranth (a plant) could change the gut bacteria in children with overweight or obesity. 56 children took part, and researchers measured their gut bacteria and blood markers. The goal was to learn more, not to treat or cure the condition.

This study looked at how malnutrition affects recovery in older adults (70+) who had broken bones like hips or shoulders. Researchers checked how common malnutrition was, tested different screening tools, and studied whether protein-rich diets helped improve outcomes. The goal wa…

This pilot study tested three simple ways to encourage blood sugar screening in 102 overweight or obese adults without known diabetes: a text message, a patient portal message, or a mailed letter. The goal was to see which method was most acceptable and effective at getting peopl…

This study looked at how certain personality traits and brain activity are linked to eating disorder symptoms in teenage girls. Researchers used brain scans to measure responses to rewards and followed up one year later to see how symptoms changed. The goal was to better understa…

This study tested a 4-month nutrition education program for 811 ethnic minority children aged 5-16 in Vietnam. The program included monthly lessons, videos, and support to improve eating habits and physical activity. Researchers compared these children to a control group to see i…

This study looked at 37 obese adults to understand why the brain's pleasure response to food is weaker in obesity. Researchers tested if insulin resistance in the brain causes this reduced response and if weight loss can improve it. The goal is to learn why weight loss is hard an…

This study tested whether a 6-month high-intensity functional training program is feasible and helpful for overweight or obese adults with long-term mobility disabilities. Twenty-five participants did exercise sessions three times a week. The goal was to see if the program could …

This study looked at how teenage girls with anorexia nervosa learn from rewards and punishments compared to healthy teens. Researchers used brain scans and computer tasks to understand differences in decision-making and brain connections. The goal was to learn more about the cond…

This study looked at how common malnutrition and muscle loss are in older adults in and out of Italian hospitals. Researchers checked 303 people aged 65 and older to understand links with diet, lifestyle, and health. The goal is to find better ways to prevent and treat malnutriti…

This study looked back at the records of over 9,000 people who had weight-loss (bariatric) surgery. The goal was to find factors that might predict bleeding during or within 30 days after surgery. By identifying these risk factors, doctors hope to create a score that can help pre…

This study looked at whether three blood proteins (pre-albumin, retinol binding protein, and transferrin) can help detect early malnutrition in people with advanced nasopharyngeal cancer undergoing chemoradiotherapy. Researchers tracked 60 patients to see if these proteins change…

This study looked at how eating more or fewer calories affects muscle protein production and muscle size in healthy middle-aged adults during a short period of leg immobilization. Twenty-three participants were monitored under different energy intake conditions. The goal is to un…

This study looked at 78 people with severe obesity who had sleeve gastrectomy surgery. Researchers wanted to see if the balance of two hormones, adiponectin and leptin, in the blood could predict how much weight they would lose. The goal is to help doctors decide who will benefit…

This study looked at 60 teens ages 12 to 18 to see if those with Avoidant and Restrictive Food Intake Disorder (ARFID) had more feeding problems before age 4 compared to healthy teens. Researchers used questionnaires to check early feeding history, growth, and sensory sensitiviti…

This study looked at levels of a hormone called prolactin in the gum fluid of 26 people with obesity and gum disease (stage II or III). Researchers measured prolactin before and after non-surgical gum treatment to see if it changed. The goal was to better understand the link betw…

This completed trial compared two types of opioid-free anesthesia—total intravenous (TIVA) versus inhaled gas—in 280 adults undergoing laparoscopic bariatric surgery. The main goal was to see which method reduces postoperative nausea and vomiting in the first 24 hours. Researcher…

This study looked at 80 people with severe obesity who had sleeve gastrectomy surgery. Researchers measured a blood protein called resistin before surgery to see if it could predict how much harmful internal belly fat patients would lose. The goal is to find a simple blood test t…

This study looked at 116 overweight or moderately obese adults who had a procedure called endoscopic sleeve gastroplasty to help them lose weight. The goal was to find out why some people lose more weight than others after the procedure. Researchers checked blood samples and medi…

This study looked at how babies suck on bottle nipples with different hole sizes. Researchers wanted to see if mothers who lost weight before pregnancy had babies with different sucking patterns. Ten mothers and their infants took part. The goal was to learn more about infant fee…

This study looked at how exercise changes body image, mood, and certain blood markers in young women aged 16-25 with restrictive eating disorders. Researchers measured responses during lab-based exercise and rest. The goal is to better understand driven exercise—a common symptom—…

This study tested a co-designed nutritional training program for 20 oncology nurses in Vietnam. The program included a three-day workshop with theory and hands-on practice, focusing on managing diet-related side effects of cancer treatment like nausea and diarrhea. Researchers me…

This study looked at how liquid versus semi-solid meals influence appetite and calorie intake in 20 healthy adults. Participants ate either a liquid meal or oatmeal with the same calories and nutrients, then later ate as much lunch as they wanted. Researchers measured how full pe…

This study looked at how common vitamin D deficiency is in people with chronic heart failure and whether giving vitamin D supplements improves their health. 91 adults with heart failure were divided into groups based on their vitamin D levels. Those with severe deficiency were ra…

This study looked at how the COVID-19 pandemic affected children with eating disorders and their families in Canada. Researchers tested virtual support groups led by parents who have been through similar experiences. They interviewed parents, youth, and healthcare workers to see …

This study tested a new computer algorithm that uses data from wearable sensors and food diaries to predict a person's real-time risk of developing prediabetes. 77 overweight or obese adults wore glucose monitors and fitness trackers for 4 months. The goal was to collect data to …

This completed study looked at how well healthy pre-menopausal women with low iron stores absorb iron from two different supplements: Spatone (a natural iron-rich water) and ferrous sulphate (a standard iron pill). Fourteen women took three different doses (5, 10, and 15 mg) of e…

This study looked at whether a ketone supplement drink can change appetite-related hormones in adults with and without obesity. Twenty-six people took part, each receiving the ketone drink on one visit and a placebo on another. Researchers measured hunger and fullness hormones be…

This study looked at whether body contouring surgery (like tummy tucks) after weight loss surgery helps people keep the weight off and affects metabolism. Researchers measured weight and certain blood markers in 60 adults before and after body contouring. The goal was to see if r…

This completed observational study from Karolinska Institutet looked at 312 children and teens with obesity who used a digital treatment tool called Evira at home. Researchers checked their medical records to see if any developed signs of disordered eating or were diagnosed with …

This small study looked at how exercise influences appetite in women who experience loss of control eating, like binge eating or bulimia. Researchers measured food intake and appetite-related hormones after exercise versus rest. The goal was to gather initial data to guide future…

This study looked at 90 children and teens (ages 7-18) taking antipsychotic medication to see how it affects their hormones, growth, and metabolism. Researchers measured prolactin levels and checked for links to sex hormones, metabolic health, and puberty development. The goal wa…

This study looked at 330 older adults (65+) who had cancer surgery to see if low albumin levels before surgery led to more complications. Researchers compared patients with low albumin to those with normal levels, tracking problems like infections, hospital stay length, and ICU n…

This study followed 201 adults with diabetes who were hospitalized for COVID-19 in Algeria. Researchers tracked their blood sugar, weight, and kidney function for up to a year after leaving the hospital. The goal was to learn how COVID-19 affects long-term diabetes control and to…

This study looked at how different types of milk—A2 milk and protein-hydrolysed lactose-free A1 milk—affect gut symptoms and inflammation in 37 adults who usually feel discomfort from regular milk. Participants drank each milk type for three days while taking either a lactase cap…

This study looked at whether 3 weeks of alternate-day fasting (eating normally one day, fasting the next) changes how the heart uses fuel compared to a typical Western diet. Sixteen overweight adults aged 55-70 with insulin resistance underwent PET scans and lab tests after each …

This study checks whether a questionnaire called SCREEN can accurately find nutrition risk in older adults (55+) who have mild cognitive impairment or dementia and live at home or in retirement homes. Researchers will compare SCREEN results to a dietitian's assessment and test if…

This study looked at 720 Indian teenagers aged 14-16 to understand how their weight (normal, overweight, or underweight) relates to their mental strength, eating habits, physical activity, and overall quality of life. Researchers surveyed students and their parents in Kolkata sch…

This study tested whether sodium phenylbutyrate can lower levels of branched chain amino acids (BCAAs) in the blood of obese and prediabetic men. High BCAAs are linked to insulin resistance and type 2 diabetes. Researchers also looked at how the drug affects blood sugar, insulin …

This study tested a program where doctors refer inactive people with chronic diseases (like diabetes, heart disease, or obesity) to an exercise professional for personalized counseling. The goal was to see if this referral scheme helps people become more active compared to just g…

This study looked at how common Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is among 459 adults in Turkey who are at risk due to being overweight, having diabetes, or other metabolic issues. Researchers used a special ultrasound to measure liver fat and stiff…

This study looked at two easy methods to measure hidden belly fat in 110 adults with type 2 diabetes. Researchers compared a simple waist measurement to a device that sends a mild electrical signal through the body. The goal was to see which method better relates to heart disease…

This study looked at how salt affects blood pressure in Black adults. Researchers wanted to see if changes in blood pressure from eating more or less salt were linked to signs seen on medical scans. 19 people took part, and the goal was to learn more, not to test a new treatment.

This study looked at how weight loss from a calorie-restricted diet affects iron levels in people with obesity and iron deficiency. Researchers measured a protein called hepcidin, which controls iron in the body, along with iron levels before and after a 60-day diet. The goal was…

This study aimed to find new blood markers that can show liver damage in people with anorexia nervosa. Researchers compared blood samples from 19 patients with and without signs of liver injury. The goal is to improve detection and understanding of liver problems in this conditio…

This study looked at how a 20% calorie-restricted diet changes metabolism in obese men of two age groups: 30-40 and 60-70 years old. Researchers measured fat breakdown at rest and during exercise, along with genetic markers in muscle and fat tissue. The goal was to understand if …

This study looked at 44 adults with obesity to see if symptoms of hyperventilation (like rapid breathing and shortness of breath) are linked to physical performance. Participants completed walking, balance, and strength tests, and reported their breathing symptoms. The goal is to…

This completed study tested whether giving families of children with long-term illnesses (like cancer, heart disease, or premature birth) a tablet computer with a special app helps them manage care at home. Researchers measured satisfaction, cost-effectiveness, and how well famil…