New Weight-Loss drug shows promise in early trial

NCT ID NCT06230523

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 study tested a new drug called eloralintide (LY3841136) for weight management in 263 adults with obesity or overweight. Participants received either the drug or a placebo for about 64 weeks. The main goal was to see how much weight they lost after 48 weeks. Results will help determine if larger studies are warranted.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Eloralintide (LY3841136)

What this could lead to

If successful, this could lead to a new medication for weight management in people with obesity or overweight.

What could go wrong

This is an early phase 2 trial with only 263 participants. The drug may not prove effective or safe in larger studies, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder overnutrition Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Arcturus Healthcare , PLC, Troy Internal Medicine Research Division

    Troy, Michigan, 48098, United States

  • CTI Clinical Research Center

    Cincinnati, Ohio, 45212, United States

  • Central Washington Health Services Association d/b/a Confluence Health

    Wenatchee, Washington, 98801, United States

  • Charter Research - Lady Lake

    The Villages, Florida, 32162, United States

  • Charter Research - Winter Park

    Orlando, Florida, 32803, United States

  • Cotton O'Neil Diabetes & Endocrinology

    Topeka, Kansas, 66606, United States

  • Dent Neurologic Institute

    Amherst, New York, 14226, United States

  • Diablo Clinical Research, Inc.

    Walnut Creek, California, 94598, United States

  • Endeavor Clinical Trials

    San Antonio, Texas, 78240, United States

  • FutureSearch Trials of Dallas

    Dallas, Texas, 75251, United States

  • Great Lakes Clinical Trials - Andersonville

    Chicago, Illinois, 60640, United States

  • Great Lakes Clinical Trials - Ravenswood

    Chicago, Illinois, 60640, United States

  • Headlands Research - Detroit

    Southfield, Michigan, 48034, United States

  • Headlands Research - Scottsdale

    Scottsdale, Arizona, 85260, United States

  • IMA Clinical Research Austin

    Austin, Texas, 78745, United States

  • Iowa Diabetes and Endocrinology Research Center

    West Des Moines, Iowa, 50265, United States

  • Knownwell

    Needham, Massachusetts, 02492, United States

  • L-MARC Research Center

    Louisville, Kentucky, 40213, United States

  • Las Vegas Medical Research

    Las Vegas, Nevada, 89128, United States

  • Lucas Research, Inc.

    New Bern, North Carolina, 28562, United States

  • Lucida Clinical Trials

    New Bedford, Massachusetts, 02740, United States

  • Medical Research Partners

    Ammon, Idaho, 83406, United States

  • Medication Management

    Greensboro, North Carolina, 27405, United States

  • Monroe Biomedical Research

    Monroe, North Carolina, 28112, United States

  • NorCal Medical Research, Inc

    Greenbrae, California, 94904, United States

  • North Suffolk Neurology

    Port Jefferson Station, New York, 11776, United States

  • NorthShore University Health System

    Skokie, Illinois, 60077, United States

  • Northeast Research Institute (NERI)

    Fleming Island, Florida, 32003, United States

  • Pacific Diabetes & Endocrine Center

    Honolulu, Hawaii, 96817, United States

  • Peninsula Research Associates

    Rolling Hills Estates, California, 90274, United States

  • PlanIt Research, PLLC

    Houston, Texas, 77079, United States

  • Quality Medical Research

    Nashville, Tennessee, 37211, United States

  • Rochester Clinical Research, LLC

    Rochester, New York, 14609, United States

  • Spectrum Medical, Inc.

    Danville, Virginia, 24541, United States

  • StudyMetrix Research

    City of Saint Peters, Missouri, 63303, United States

  • Suncoast Clinical Research, Inc.

    New Port Richey, Florida, 34652, United States

  • Tekton Research - Fredericksburg Road

    San Antonio, Texas, 78229, United States

  • The Institute for Liver Health II dba Arizona Clinical Trials - Mesa

    Chandler, Arizona, 85225, United States

  • The Institute for Liver Health II dba Arizona Liver Health-Tucson

    Tucson, Arizona, 85712, United States

  • Tribe Clinical Research, LLC

    Greenville, South Carolina, 29607, United States

  • Velocity Clinical Research, Dallas

    Dallas, Texas, 75230, United States

  • Velocity Clinical Research, Huntington Park

    Huntington Park, California, 90255, United States

  • Velocity Clinical Research, Syracuse

    East Syracuse, New York, 13057, United States