New Weight-Loss drug shows promise in early trial

NCT ID NCT06230523

Completed Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 study tested a new drug called eloralintide (LY3841136) for weight management in 263 adults with obesity or overweight. Participants received either the drug or a placebo for about 64 weeks. The main goal was to see how much weight they lost after 48 weeks. Results will help determine if larger studies are warranted.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Eloralintide (LY3841136)
What this could lead to: If successful, this could lead to a new medication for weight management in people with obesity or overweight.
What could go wrong: This is an early phase 2 trial with only 263 participants. The drug may not prove effective or safe in larger studies, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder overnutrition Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY OVERWEIGHT

Contacts and locations

Locations

Arcturus Healthcare , PLC, Troy Internal Medicine Research Division

Troy, Michigan, 48098, United States
CTI Clinical Research Center

Cincinnati, Ohio, 45212, United States
Central Washington Health Services Association d/b/a Confluence Health

Wenatchee, Washington, 98801, United States
Charter Research - Lady Lake

The Villages, Florida, 32162, United States
Charter Research - Winter Park

Orlando, Florida, 32803, United States
Cotton O'Neil Diabetes & Endocrinology

Topeka, Kansas, 66606, United States
Dent Neurologic Institute

Amherst, New York, 14226, United States
Diablo Clinical Research, Inc.

Walnut Creek, California, 94598, United States
Endeavor Clinical Trials

San Antonio, Texas, 78240, United States
FutureSearch Trials of Dallas

Dallas, Texas, 75251, United States
Great Lakes Clinical Trials - Andersonville

Chicago, Illinois, 60640, United States
Great Lakes Clinical Trials - Ravenswood

Chicago, Illinois, 60640, United States
Headlands Research - Detroit

Southfield, Michigan, 48034, United States
Headlands Research - Scottsdale

Scottsdale, Arizona, 85260, United States
IMA Clinical Research Austin

Austin, Texas, 78745, United States
Iowa Diabetes and Endocrinology Research Center

West Des Moines, Iowa, 50265, United States
Knownwell

Needham, Massachusetts, 02492, United States
L-MARC Research Center

Louisville, Kentucky, 40213, United States
Las Vegas Medical Research

Las Vegas, Nevada, 89128, United States
Lucas Research, Inc.

New Bern, North Carolina, 28562, United States
Lucida Clinical Trials

New Bedford, Massachusetts, 02740, United States
Medical Research Partners

Ammon, Idaho, 83406, United States
Medication Management

Greensboro, North Carolina, 27405, United States
Monroe Biomedical Research

Monroe, North Carolina, 28112, United States
NorCal Medical Research, Inc

Greenbrae, California, 94904, United States
North Suffolk Neurology

Port Jefferson Station, New York, 11776, United States
NorthShore University Health System

Skokie, Illinois, 60077, United States
Northeast Research Institute (NERI)

Fleming Island, Florida, 32003, United States
Pacific Diabetes & Endocrine Center

Honolulu, Hawaii, 96817, United States
Peninsula Research Associates

Rolling Hills Estates, California, 90274, United States
PlanIt Research, PLLC

Houston, Texas, 77079, United States
Quality Medical Research

Nashville, Tennessee, 37211, United States
Rochester Clinical Research, LLC

Rochester, New York, 14609, United States
Spectrum Medical, Inc.

Danville, Virginia, 24541, United States
StudyMetrix Research

City of Saint Peters, Missouri, 63303, United States
Suncoast Clinical Research, Inc.

New Port Richey, Florida, 34652, United States
Tekton Research - Fredericksburg Road

San Antonio, Texas, 78229, United States
The Institute for Liver Health II dba Arizona Clinical Trials - Mesa

Chandler, Arizona, 85225, United States
The Institute for Liver Health II dba Arizona Liver Health-Tucson

Tucson, Arizona, 85712, United States
Tribe Clinical Research, LLC

Greenville, South Carolina, 29607, United States
Velocity Clinical Research, Dallas

Dallas, Texas, 75230, United States
Velocity Clinical Research, Huntington Park

Huntington Park, California, 90255, United States
Velocity Clinical Research, Syracuse

East Syracuse, New York, 13057, United States

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