Can a steady drip of local anesthetic speed recovery after open-heart surgery?

NCT ID NCT01828788

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial tests whether a continuous infusion of the local anesthetic ropivacaine, delivered through small catheters placed near the breastbone, can improve recovery after cardiac surgery. The study focuses on patients at higher risk of respiratory complications, such as older adults, those with obesity, or those with chronic bronchitis. The goal is to see if better pain control can help patients cough, breathe deeply, and move earlier, potentially reducing lung complications and shortening hospital stays.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Ropivacaine, a local anesthetic, delivered continuously through small catheters placed near the breastbone after cardiac surgery
What this could lead to
If effective, this approach could reduce respiratory complications and shorten hospital stays for patients at higher risk after cardiac surgery.
What could go wrong
This is a phase 2 trial, so results are preliminary. The benefit may be modest, and there are risks associated with the catheter placement and local anesthetic infusion.

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Conditions

The condition(s) this trial relates to.

chronic bronchitis Obesity obesity disorder Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003, France

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