Fiber-Rich diet may tame blood sugar and hunger in overweight adults

NCT ID NCT06416254

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a diet packed with fiber, but lower in calories and sugar, helps control blood sugar after meals and keeps people feeling full. Twenty-four overweight or obese adults ate either the high-fiber diet or a typical Western diet for a short period. Researchers measured blood sugar continuously and asked participants about hunger and fullness. The goal was to see if the fiber-rich diet is both well-tolerated and effective for managing appetite and blood sugar.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

24 people

The number who actually took part.

Started

Mar 2024

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Be willing and able to give written informed consent. * Be between 18 and 45 years of age * Have a Body Mass Index (BMI) of 25-34.9kg/m2 (Overweight or Obese Class I) * Have had a stable body weight (≤5% change over the past three months) * Be in general good health as determined by the investigator through interview and vital signs (blood pressure, pulse, temperature). Systolic blood pressure less than 160mm Hg and diastolic blood pressure less than 100 mm Hg (defined as Hypertension stage 2). * Be willing to avoid consuming dietary supplements, prebiotics, probiotics, or fibre-rich supplements within four weeks prior to the baseline visit, and until the end of the study. * Be willing to avoid physical exercise for the duration of the study (physical exercise defined as any physical activity that is planned to achieve a fitness goal) * Be willing to consume the investigational products daily for the duration of the study. Exclusion Criteria: * Pregnant, lactating, menopausal or post-menopausal women, or women who are planning to become pregnant over the study period. * Have had antibiotic treatment within three months prior to baseline. * Are taking a medication that the investigator believes would interfere with the objectives of the study, pose a safety risk, or confound the interpretation of study results; to include: anti-inflammatory drugs, H2 blockers, antacid, proton pump inhibitors, anti-hypertensive medications, corticosteroids, laxatives, enemas, antibiotics, anti-coagulants, immunosuppressant medication. Participants should have a wash-out period of at least two-weeks for each of these medications except for antibiotics, which should not have been taken in the previous three months. Participants taking proton pump inhibitors and medications for chronic conditions (e.g., anti-hypertensive medication) will be allowed onto the study if the dose has been stable for at least two months prior to the study baseline visit. * Have a history or indication of drug and/or alcohol abuse at the time of enrolment. * Have a habitual alcohol consumption of \>2 alcoholic beverages/day (\>28g ethanol daily). * Follow a vegetarian or vegan diet * Have a typical fibre intake of \>30g per day * Have experienced major dietary changes within three months prior to the study baseline. * Plan major lifestyle changes (diet, physical activity, or travel) during the study period. * Have a clinically diagnosed eating disorder. * Have a food allergy or intolerance that would preclude study product intake (for example eggs, gluten, nuts, milk or any other food allergy or intolerance) * Have an active gastrointestinal disorder or previous gastrointestinal surgery * Have a significant active and medically-diagnosed acute or chronic co-existing illness including: metabolic, psychiatric, cardiovascular, endocrinological, immunological condition, gastrointestinal disease or any other condition which contraindicates, in the investigator's judgement, entry to the study (such as, diarrhoea, Crohn's disease, ulcerative colitis, irritable bowel syndrome, diverticulosis, stomach or duodenal ulcers, hepatitis A/B/C, HIV, cancer, diabetes etc) or a significant history of such diseases. * Are severely immunocompromised (e.g., HIV positive, transplant patient, on anti-rejection medications, on a steroid for \>30 days, or chemotherapy or radiotherapy within the last 12 months). * Have a malignant disease or concomitant end-stage organ disease. * Have symptomatic respiratory or cardiac illness. * Experience alarm features such as sudden weight loss, rectal bleeding, a recent change in bowel habits, or significant abdominal pain within three months prior to baseline. * Individuals who, in the opinion of the investigator are poor attendees or unlikely for any reason to be able to comply with the study protocol. * Participants may not be receiving treatment involving experimental drugs. * If the participant has been in a recent experimental trial, these must have been completed not less than 30 days prior to this study. * Individuals with pacemakers or implantable cardioverter defibrillators. * Individuals that regularly undertake rigorous exercise, defined by International Physical Activity Questionnaire with a score within category 3, Health Enhancing Physical Activity (HEPA) Active. * Individuals who smoke or vape regularly (i.e., daily or habitual use).

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Overweight and obesity are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University College Cork

    Cork, Cork, Ireland

More trials for these conditions

Other studies related to the condition(s) this trial covers.