Calories vs. couch time: can diet save your muscles?

NCT ID NCT04900701

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how eating more or fewer calories affects muscle protein production and muscle size in healthy middle-aged adults during a short period of leg immobilization. Twenty-three participants were monitored under different energy intake conditions. The goal is to understand how diet might help prevent muscle loss when people are less active.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could help design better dietary strategies to prevent muscle loss during periods of inactivity, like bed rest or recovery from injury.

What could go wrong

This is a small, early-stage observational study with only 23 participants. Results may not apply to older adults or people with health conditions, and the findings are not a treatment or cure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

muscular atrophy protein-energy malnutrition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sport & Health Sciences University of Exeter

    Exeter, Devon, EX1 2LU, United Kingdom

  • University of Exeter, Sports & Health Sciences, College of Life & Environmental Sciences

    Exeter, Devon, EX1 2LU, United Kingdom