University Of Exeter

This study looks at whether a structured exercise program can help overweight and obese women aged 25-50 maintain muscle mass and physical function while taking the weight-loss drug tirzepatide. Participants will be split into two groups: one taking tirzepatide alone, and the oth…

This study tests a smart wearable device called gaitQ that uses cues to help people with long-term movement conditions like Parkinson's disease, stroke, multiple sclerosis, and arthritis walk better. Researchers will measure walking improvements in 150 participants, including hea…

This study uses special brain scans to look at damage to nerve cell connections (synapses) in people with two rare brain diseases: Multiple System Atrophy (MSA) and Progressive Supranuclear Palsy (PSP). About 36 adults aged 45-80 will be scanned over a year to track how the disea…

This study looks at babies diagnosed with type 1 diabetes before age 2, a very rare and extreme form of the disease. Researchers want to understand what goes wrong in the immune system that destroys insulin-making cells so early. By studying these children and comparing them to o…

This study aims to understand how inflammation in the brain contributes to Parkinson's disease. Researchers will give a mild inflammatory substance (LPS) to 30 participants, including people with Parkinson's, those with REM sleep behavior disorder, and healthy volunteers. They wi…

This study uses special brain scans (PET, SPECT, and MRI) to learn more about the brain changes that happen in Parkinson's disease. Researchers want to find a biological marker that could help develop new medicines to slow down the disease. The study involves 42 adults aged 25 to…

This study uses special brain scans (PET, SPECT, and MRI) to find markers of Parkinson's disease in people with certain genetic mutations. Researchers will look at changes in brain chemicals and structure to better understand the disease. The goal is to help develop new treatment…

This study looks at how rare genetic changes affect beta cells, which control blood sugar. Researchers will compare people with and without these gene variants using blood tests and optional MRI scans. There is no treatment involved, and participants continue their normal care. T…

This study aims to find a biological marker for Parkinson's disease by using special brain scans (PET, SPECT, and MRI). Researchers will track 44 participants over time to see how certain brain cells and chemicals change as the disease progresses. The goal is to better understand…

This study looks at whether a special high-protein sauce can help older adults absorb essential amino acids better than a regular low-protein sauce. Researchers want to see if the sauce provides more nutrition without making people feel too full. Twenty adults aged 60 and older w…