Rare baby diabetes study could rewrite treatment rules

NCT ID NCT03369821

Recruiting now Knowledge-focused Sponsor: University of Exeter Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at babies diagnosed with type 1 diabetes before age 2, a rare and extreme form of the disease. Researchers want to understand what goes wrong in the immune system to cause such early onset. By studying these children and comparing them to others with diabetes and healthy controls, they hope to find new ways to delay or prevent type 1 diabetes in everyone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could identify new drug targets to delay or prevent type 1 diabetes in all age groups.
What could go wrong: This is an observational study, not a treatment trial. Findings may not translate into therapies, and the very small patient group may not represent typical diabetes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

neonatal diabetes mellitus type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE1 DIABETES MELLITUS

Contacts and locations

Locations

Benaroya Research Institute
NOT_YET_RECRUITING

Seattle, Washington, 98101-2795, United States
King's College London
ACTIVE_NOT_RECRUITING

London, SE1 9RT, United Kingdom
Leiden University Medical Center
NOT_YET_RECRUITING

Leiden, Leiden, 2333 ZA, Netherlands
Royal Devon & Exeter NHS Foundation Trust
RECRUITING

Exeter, Devon, EX2 5DW, United Kingdom

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