Could a keto diet tame prediabetes inflammation?

NCT ID NCT06911879

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a low-carb, high-fat ketogenic diet with fewer calories can reduce inflammation and improve blood sugar control in prediabetic obese adults aged 18 to 40. Ninety participants were split into three groups: a keto diet, a normal diet with fewer calories, or a normal diet without calorie restriction. The main focus was on changes in blood markers of inflammation and insulin resistance over 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ketogenic diet with caloric restriction
What this could lead to
If successful, this could point toward a dietary approach to reduce inflammation and improve insulin sensitivity in people with prediabetes and obesity.
What could go wrong
This is a small, completed trial with 90 participants, so results may not apply to broader populations. Dietary adherence can be challenging, and the long-term effects of a ketogenic diet are not fully known.

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Conditions

The condition(s) this trial relates to.

Inflammation Insulin Resistance Obesity obesity disorder prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aseel nutrition center

    Amman, Jordan

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