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Lifestyle coaching may be key to keeping weight off after stopping obesity drugs

NCT ID NCT05608226

Disease control Sponsor: Shanghai Zhongshan Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study tests whether a remotely delivered lifestyle education program can help people who have lost weight with medication keep that weight off after they stop taking the drugs. Participants are adults who lost at least 5% of their body weight during a previous pharmacotherapy trial. The program focuses on healthy eating, physical activity, and behavior change, and the study tracks weight, blood lipids, blood sugar, and blood pressure over six months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Lifestyle Education Program
What this could lead to
If successful, this could show that a structured lifestyle program helps people keep weight off after stopping weight-loss drugs.
What could go wrong
This is a small, early-stage study in Chinese adults only, so results may not apply to other groups. Lifestyle adherence can be challenging, and weight regain may still occur.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

128 people

The number who actually took part.

Started

Sep 2022

Finished

Jul 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Subjects who completed a pharmacotherapy trial with clinically meaningful weight loss (≥5%) and consented to this study.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All patients who completed a pharmacotherapy trial with clinically meaningful weight loss (≥5%) * Those who consent to this study Exclusion Criteria: * Those who do not consent to this study

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Conditions

The condition(s) this trial relates to.

Body-Weight Trajectory obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Body-weight trajectory

Contacts and locations

Locations

  • Xiaoying Li

    Shanghai, China

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