Can vyvanse curb Post-Surgery binge eating? new trial aims to find out

NCT ID NCT04599504

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the medication lisdexamfetamine (Vyvanse) can help people who experience loss-of-control eating after bariatric surgery and didn't improve with earlier treatments. About 60 adults who had gastric bypass or sleeve gastrectomy will receive either the drug or a placebo daily for several months. Researchers will track changes in eating episodes and body mass index to see if the medication offers real benefits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lisdexamfetamine (Vyvanse)

What this could lead to

If it works, this could offer a medication option to help people who struggle with loss-of-control eating after bariatric surgery, potentially improving their weight outcomes.

What could go wrong

This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. The medication may cause side effects or not work better than a placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

binge eating disorder Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Yale School of Medicine

    New Haven, Connecticut, 06519, United States