Could a probiotic boost weight loss after surgery?
NCT ID NCT05170867
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether taking a probiotic called Hafnia alvei HA4597 can help people lose more weight and control blood sugar better after gastric bypass surgery. 49 adults with obesity and type 2 diabetes took either the probiotic or a placebo twice a day for 90 days, starting one month after surgery. Researchers tracked weight loss and blood sugar levels over a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hafnia alvei HA4597 probiotic supplement
What this could lead to
If it works, this could point toward a simple probiotic to help people lose more weight and control blood sugar after weight-loss surgery.
What could go wrong
This is a small, early-stage trial with only 49 participants. The results may not apply to everyone, and the supplement may not provide any extra benefit beyond standard care.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa
Lisbon, 1169-056, Portugal