Cialis for weight loss? study tests Fat-Burning effects
NCT ID NCT04684589
First seen Jun 20, 2026 · Last updated Jun 20, 2026
Summary
This study tested whether taking tadalafil (Cialis) daily for 12 weeks can change how fat tissue works in obese adults. Researchers used MRI scans and fat samples to measure fat metabolism and gene activity. The goal was to understand if the drug could make fat behave more like calorie-burning brown fat, not to cause weight loss directly.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Vanderbilt University Medical Center
Nashville, Tennessee, 37203, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tadalafil (Cialis)
What this could lead to
If successful, this could point toward a new way to treat obesity by changing how the body stores and burns fat.
What could go wrong
This is an early-stage study with only 89 participants. It measures biological changes, not weight loss, so even positive results may not lead to a practical treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.