Weight-Loss drug semaglutide tested for Long-Term appetite control

NCT ID NCT05548647

First seen Oct 31, 2025 · Last updated Apr 29, 2026 · Updated 19 times

Summary

This study looked at how the weight-loss medication semaglutide affects appetite, eating behavior, and food preferences over 72 weeks. 120 adults with obesity or overweight plus related health issues took either semaglutide or a placebo, along with diet and exercise counseling. The goal was to see if the drug helps reduce calorie intake and improve eating habits long-term.

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Contacts and locations

Locations

  • University of Pennsylvania Center for Weight and Eating Disorders

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.